Dietary bisphenol A prevents ovarian degeneration and bone loss in female mice lacking the aromatase gene (Cyp19)

European Journal of Biochemistry

Volumn 269, Issue 8, 2002, Pages 2214-2222

  Toda, Katsumi ^a   Miyaura, Chisato ^b   Okada, Teruhiko ^a   Shizuta, Yutaka ^a  

^a KOCHI MEDICAL SCHOOL   (Japan)

^b TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

ArKO mouse; Bisphenol A; Estrogens; IGF I

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; AROMATASE; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 15; ESTROGEN; GROWTH DIFFERENTIATION FACTOR 9; MESSENGER RNA; MONOMER; POLYCARBONATE; PROGESTERONE RECEPTOR; RNA; SOMATOMEDIN; SOMATOMEDIN RECEPTOR; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE ATROPHY; CONTROLLED STUDY; DEGENERATION; DIET; DIET SUPPLEMENTATION; DOSE RESPONSE; ESTROGEN ACTIVITY; FEEDING; FEMALE; GENDER; GENE DELETION; GENITAL SYSTEM; HORMONE DETERMINATION; IN VIVO STUDY; MOUSE; MOUSE STRAIN; NONHUMAN; NORTHERN BLOTTING; OVARY; OVARY DEGENARATION; PHENOTYPE; PRIORITY JOURNAL; PROTECTION; PROTEIN EXPRESSION; RNA ANALYSIS; SKELETON; STRUCTURE ANALYSIS; SYNTHESIS; UTERUS; UTERUS DISEASE; WILD TYPE;

ANIMALS; AROMATASE; BONE AND BONES; BONE RESORPTION; DIET; ESTROGENS, NON-STEROIDAL; FEMALE; MICE; OVARIAN DISEASES; OVARY; PHENOLS; UTERUS;

ANIMALIA; FALLOPIA; VERTEBRATA;

EID: 0036233612     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1033.2002.02879.x     Document Type: Article

References (44)

1. Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis
2. Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene
3. Disruption of sexual behavior in male aromatase-deficient mice lacking exons 1 and 2 of the cyp 19 gene
4. Targeted disruption of the aromatase P450 gene (Cyp19) in mice and their ovarian and uterine responses to 17β-oestradiol
5. An age-related ovarian phenotype in mice with targeted disruption of the Cyp 19 (aromatase) gene
6. Bone has a sexually dimorphic response to aromatase deficiency
7. Sex- and age-related response to aromatase-deficiency in bone
8. Oestrogen at the neonatal stage is critical for reproductive ability of male mice as revealed by supplementation with 17β-oestradiol to aromatase gene (Cyp19) knockout mice
9. Impairment of spermatogenesis in mice lacking a functional aromatase (cyp19) gene
10. A loss of aggressive behaviour and its reinstatement by estrogen in mice lacking the aromatase gene (Cyp19)
11. Altered expression of fatty acid-metabolizing enzymes in aromatase-deficient mice
12. Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity
13. Editorial: Surprising places of estrogenic activity
14. Uterotrophic activity of bisphenol A in the immature rat
15. The rodent uterotropic assay: Critical protocol features, studies with nonyl phenols, comparison with a yeast estrogenicity assay
16. Do environmental estrogens contribute to the decline in male reproductive health?
17. Xenoestrogens released from lacquer coatings in food cans
18. Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor β
19. Determining relative estrogenicity by quantifying vitellogenin induction in rainbow trout liver slices
20. Estrogenicity of bisphenol A and bisphenol A dimethacrylate in vitro
21. Applicability of a yeast oestrogen screen for the detection of oestrogen-like activities in environmental samples
22. Exposure to bisphenol A advances puberty
23. Simultaneous banding of rat embryo DNA, RNA, and protein in cesium trifluoroacetate gradients
24. Tail bleeding
25. Importance of the IGF system in early folliculogenesis
26. Effects of an igf1 gene mutation on mouse reproduction
27. The mouse intraovarian insulin-like growth factor I system: Departures from the rat paradigm
28. Mutations in an oocyte-derived growth factor gene (BMP15) cause increased ovulation rate and infertility in a dosage-sensitive manner
29. Synergistic roles of bone morphogenetic protein 15 and growth differentiation factor 9 in ovarian function
30. Growth differentiation factor 9 is required during early ovarian folliculogenesis
31. Molecular charactrization of the follicle defects in the growth differentiation factor-9-deficient ovary
32. Impairing follicle-stimulating hormone (FSH) signaling in vivo: Targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance
33. The effect of a null mutation in the follicle-stimulating hormone receptor gene on mouse reproduction
34. Relative binding affinity-serum modified access (RBA-SMA) assay predicts the relative in vivo bioactivity of the xenoestrogens bisphenol A and octylphenol
35. Obstacles to the prediction of estrogenicity from chemical structure: Assay-mediated metabolic transformation and the apparent promiscuous nature of the estrogen receptor
36. Glucuronidation of the environmental oestrogen bisphenol A by an isoform of UDP-glucuronosyltransferase, UGT2B1, in the rat liver
37. Differential regulation of two uridine diphospho-glucuronosyltransferases, UGT2B15 and UGT2B17, in human prostate LNCaP cells
38. Serum bisphenol A concentrations showed gender differences, possibly linked to androgen levels
39. Oocyte-expressed TGF-β superfamily members in female fertility
40. Selective effects of genistein, a soybean isoflavone, on B-lymphopoiesis and bone loss caused by estrogen deficiency
41. Bisphenol-A: An estrogenic substance is released from polycarbonate flasks during autoclaving
42. Normal reproductive organ development in CF-1 mice following prenatal exposure to bisphenol A
43. Lack of effects for low dose levels of bisphenol A and diethylstilbestrol on the prostate gland of CF1 mice exposed in utero