Evidence for a sustained increase in clonal β-cell basal intracellular Ca2+ levels after incubation in the presence of newly diagnosed Type-1 diabetic patient sera. Possible role in serum-induced inhibition of insulin secretion

Journal of Endocrinology

Volumn 173, Issue 1, 2002, Pages 53-62

  Conroy, S J ^a   Green, I ^a   Dixon, G ^a   Byrne, P M ^a   Nolan, J ^a   Abdel Wahab, Y H A ^a   McClenaghan, N ^a   Flatt, P R ^a   Newsholme, P ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C3; CYTOKINE; DNA FRAGMENT; GAMMA INTERFERON; INTERLEUKIN 1BETA; NITRIC OXIDE; NITRITE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; APOPTOSIS; CALCIUM CELL LEVEL; CELL CLONE; CELL DEATH; CELL VIABILITY; CLINICAL ARTICLE; COMPLEMENT SYSTEM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DESENSITIZATION; FEMALE; FETAL CALF SERUM; HUMAN; HUMAN CELL; INCUBATION TIME; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; MALE; NUTRIENT; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; REVIEW; SERUM;

ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; CALCIUM; CELL LINE; COMPLEMENT C1Q; COMPLEMENT C3; COMPLEMENT SYSTEM PROTEINS; CULTURE MEDIA; CYTOKINES; DIABETES MELLITUS, TYPE 1; HUMANS; INSULIN; INTERFERON TYPE II; INTERLEUKIN-1; ISLETS OF LANGERHANS; NITRITES; RATS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036233140     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1730053     Document Type: Review

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