Complex SNP-based haplotypes in three human helicases: Implications for cancer association studies

Genome Research

Volumn 12, Issue 4, 2002, Pages 627-639

  Trikka, Dimitra ^a   Fang, Zhe ^b   Renwick, Alex ^c   Jones, Sally H ^a   Chakraborty, Ranajit ^a   Kimmel, Marek ^a,c   Nelson, David L ^c  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c Rice University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HELICASE;

ARTICLE; CANCER SUSCEPTIBILITY; CHROMOSOME; CONTROLLED STUDY; DNA DETERMINATION; ETHNIC DIFFERENCE; ETHNIC GROUP; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE MUTATION; GENE SEGREGATION; GENE SEQUENCE; GENETIC CODE; GENETIC RECOMBINATION; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; HUMAN CELL; JEW; MOLECULAR EVOLUTION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; UNITED STATES;

ALLELES; ANIMALS; DNA HELICASES; DNA MUTATIONAL ANALYSIS; GENE FREQUENCY; GORILLA GORILLA; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; MOLECULAR SEQUENCE DATA; NEOPLASMS; OLIGONUCLEOTIDE PROBES; PAN PANISCUS; PAN TROGLODYTES; PHYLOGENY; PILOT PROJECTS; POLYMORPHISM, SINGLE NUCLEOTIDE; RECOMBINATION, GENETIC; VARIATION (GENETICS);

PRIMATES;

EID: 0036228661     PISSN: 10889051     EISSN: None     Source Type: Journal    
DOI: 10.1101/gr.176702     Document Type: Article

References (55)

1. Update on human gene mutations
2. Haplotypes at ATM identify coding-sequence variation and indicate a region of extensive linkage disequilibrium
3. Characterization of single-nucleotide polymorphisms in coding regions of human genes
4. Polymorphisms at the Werner locus: I. Newly identified polymorphisms, ethnic variability of 1367Cys/Arg, and its stability in a population of Finnish centenarians
5. Gene diversity and estimation of genetic admixture among Mexican-Americans of Starr County, Texas
6. Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase
7. A robotics-assisted procedure for large scale cystic fibrosis mutation analysis
8. The Bloom's syndrome gene product is homologous to RecQ helicases
9. Ash is present in non-Jewish Americans of Spanish ancestry
10. Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population
11. Characterization of a new BLM mutation associated with a topoisomerase II α defect in a patient with Bloom's syndrome
12. New statistical tests of neutrality for DNA samples from population
13. Mutator phenotype of Werner syndrome is characterized by extensive deletions
14. Bloom syndrome: A mendelian prototype of somatic mutational disease
15. Linkage disequilibrium and allele-frequency distributions for 114 single-nucleotide polymorphisms in five populations
16. Family analysis of Werner's syndrome: A survey of 42 Japanese families with a review of the literature
17. Excess of rare cancers in Werner syndrome (adult progeria)
18. The Werner syndrome protein is a DNA helicase
19. Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis
20. p53 polymorphism and risk of cervical cancer
21. Statistical properties of the number of recombination events in the history of a sample of DNA sequences
22. p53 polymorphism and risk of cervical cancer
23. The Bloom's syndrome gene product is a 3′-5′ DNA helicase
24. A global survey of haplotype frequencies and linkage disequilibrium at the DRD2 locus
25. Haplotypes and linkage disequilibrium at the phenylalanine hydroxylase locus, PAH, in a global representation of populations
26. Hereditary cancer: Two hits revisited
27. The use of a genetic map of biallelic markers in linkage studies
28. Prospects for whole-genome linkage disequilibrium mapping of common disease genes
29. Increasing the information content of STS-based genome maps: Identifying polymorphisms in mapped STSs
30. A 4-Mb high-density single nucleotide polymorphism-based map around human APOE
31. The interaction of selection and linkage. I. General considerations; heterotic models
32. The evolutionary dynamics of complex polymorphisms
33. Neutral sequence variants and haplotypes at the 150 kb ataxia-telangiectasia locus
34. The power of association studies to detect the contribution of candidate genetic loci to variation in complex traits
35. Analysis of association at single nucleotide polymorphisms in the APOE region
36. Werner syndrome: Characterization of mutations in the WRN gene in an affected family
37. WRN mutations in Werner syndrome
38. DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene
39. Variation in the interleukin 4-receptor α gene confers susceptibility to asthma and atopy in ethnically diverse populations
40. Cloning and characterization of RECQL, a potential human homologue of the Escherichia coli DNA helicase RecQ
41. The future of genetic studies of complex human diseases
42. Ashkenazi Jewish population frequency of the Bloom syndrome gene 2281 delta 6ins7 mutation
43. DnaSP, DNA sequence polymorphism: An interactive program for estimating population genetics parameters from DNA sequence data
44. DnaSP version 3: An integrated program for molecular population genetics and molecular evolution analysis
45. High frequency of a common Bloom syndrome Ashkenazi mutation among Jews of Polish origin
46. Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
47. Role of a p53 polymorphism in the development of human papillomavirus-associated cancer
48. Allelic disequilibrium and allele frequency distribution as a function of social and demographic history
49. Escherichia coli RecQ protein is a DNA helicase
50. The 1396del A mutation and a missense mutation or a rare polymorphism of the WRN gene detected in a French Werner family with a severe phenotype and a case of an unusual vulvar cancer
51. Global sequence diversity of BRCA2: Analysis of 71 breast cancer families and 95 control individuals of worldwide populations
52. Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome
53. Association of a polymorphic variant of the Werner helicase gene with myocardial infarction in a Japanese population
54. Positional cloning of the Werner's syndrome gene