The biological roles of trans-translation

Current Opinion in Microbiology

Volumn 5, Issue 2, 2002, Pages 154-159

  Withey, Jeffrey H ^a   Friedman, David I ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEINASE; REGULATOR PROTEIN; TRANSFER RNA;

BACTERIAL SURVIVAL; GENE EXPRESSION REGULATION; PROTEIN DEGRADATION; PROTEIN TARGETING; REVIEW; RIBOSOME; TRANSLATION REGULATION;

BACTERIA (MICROORGANISMS);

EID: 0036221089     PISSN: 13695274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1369-5274(02)00299-0     Document Type: Review

References (51)

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4. Emerging views on tmRNA-mediated protein tagging and ribosome rescue
5. Probing the structure of the Escherichia coli 10Sa RNA (tmRNA)
6. Phylogenetic analysis of tmRNA secondary structure
7. Presence and location of modified nucleotides in Escherichia coli tmRNA: Structural mimicry with tRNA acceptor branches
8. Comparative sequence analysis of tmRNA
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10. Structural studies of the tRNA domain of tmRNA
11. Importance of the conserved nucleotides around the tRNA-like structure of Escherichia coli transfer-messenger RNA for protein tagging
12. Phylogenetic analysis of tmRNA genes within a bacterial subgroup reveals a specific structural signature
13. Three of four pseudoknots in tmRNA are interchangeable and are substitutable with single-stranded RNAs
14. A tRNA-like structure is present in 10Sa RNA, a small stable RNA from Escherichia coli
15. C-terminal extension of truncated recombinant proteins in Escherichia coli with a 10Sa RNA decapeptide
16. Role of a peptide tagging system in degradation of proteins synthesized from damaged messenger RNA
17. Interaction of 10Sa RNA with ribosomes in Escherichia coli
18. 10Sa RNA is associated with 70S ribosome particles in Escherichia coli
19. Binding and cross linking of tmRNA to ribosomal protein S1, on and off the Escherichia coli chromosome
20. Protein factors associated with the SsrA SmpB tagging and ribosome rescue system
21. Aminoacylated tmRNA from Escherichia coli interacts with prokaryotic elongation factor Tu
22. Kinetic parameters for tmRNA binding to Alanyl-tRNA synthetase and elongation factor Tu from Escherichia coli
23. Complex of transfer-messenger RNA and elongation factor Tu. Unexpected modes of interaction
24. Simultaneous and functional binding of SmpB and EF-Tu-GTP to the alanyl acceptor arm of tmRNA
25. In vitro trans-translation mediated by alanine-charged 10Sa RNA
26. Amino acid acceptor identity switch of Escherichia coli tmRNA from alanine to histidine in vitro
27. Resuming translation on tmRNA: A unique mode of determining a reading frame
28. Determinants on tmRNA for initiating efficient and precise trans-translation: Some mutations upsteam of the tag-encoding sequence of Escherichia coli tmRNA shift the initiation point of trans-translation in vivo
29. Transfer RNA-Ala recognizes transfer messenger RNA with specificity; a functional complex prior to entering the ribosome?
30. The ClpXP and ClpAP proteases degrade proteins with carboxy-terminal peptide tails added by the SsrA-tagging system
31. Degradation of C-terminal-tagged cytoplasmic proteins by the Escherichia coli protease HflB (FtsH)
32. SmpB, a unique RNA-binding protein essential for the peptide-tagging activity of SsrA (tmRNA)
33. A specificity-enhancing factor for the ClpXP degradation machine
34. Overlapping recognition determinants within the ssrA degradation tag allow modulation of proteolysis
35. Analysis of the role of trans-translation in the requirement of tmRNA for lambda-immP22 growth in Escherichia coli
36. Formation of hybrids between coliphage lambda and Salmonella phage P22 with a Salmonella typhimurium hybrid sensitive to these phages
37. Specificity of genetic elements controlling regulation of early functions in temperate bacteriophages
38. ssrA (tmRNA) plays a role in Salmonella enterica serovar Typhimurium pathogenesis
39. Role for 10Sa RNA in the growth of lambda-P22 hybrid phage
40. SsrA-mediated peptide tagging caused by rare codons and tRNA scarcity
41. Identification of endogenous SsrA-tagged proteins reveals tagging at positions corresponding to stop codons
42. Charged tmRNA but not tmRNA-mediated proteolysis is essential for Neisseria gonorrhoeae viability
43. The tRNA function of SsrA contributes to controlling repression of bacteriophage Mu prophage
44. SsrA-mediated tagging and proteolysis of Lacl and its role in the regulation of lac operon
45. Temperature-sensitive mutations in various genes of Escherichia coli K12 can be suppressed by the ssrA gene for 10Sa RNA (tmRNA)
46. 10Sa RNA complements the temperature-sensitive phenotype caused by a mutation in the phosphoribosyl pyrophosphate synthetase (prs) gene in Escherichia coli
47. SsrA-mediated tagging in Bacillus subtilis
48. Requirement of transfer-messenger RNA for the growth of Bacillus subtilis under stresses
49. Virulence regions and virulence factors of the ovine footrot pathogen, Dichelobacter nodosus
50. Increased sensitivity to protein synthesis inhibitors in cells lacking tmRNA