Blood meal acquisition by ticks; molecular advances and implications for vaccine development

Japanese Journal of Veterinary Research

Volumn 49, Issue 4, 2002, Pages 261-272

  Mulenga, Albert ^a   Tsuda, Akiko ^a   Sugimoto, Chihiro ^a   Onuma, Misao ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Hemostasis; Platelet aggregation; Tick vaccine development; Vasodilation

Indexed keywords

5' NUCLEOTIDASE; ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; ANTITHROMBOCYTIC AGENT; APYRASE; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 10A; COLLAGEN; COMPLEMENTARY DNA; DECORSIN; DISAGREGIN; DISINTEGRIN; FIBRIN; FIBRINOGEN RECEPTOR; FIBRINOGEN RECEPTOR ANTAGONIST; HEPARIN; MOUBATIN; ORNATIN; PARASITE ANTIGEN; THROMBIN; THROMBOPLASTIN; THROMBOXANE; TICK ANTICOAGULANT PEPTIDE; UNCLASSIFIED DRUG; VACCINE; VARIABILIN; VASODILATOR AGENT; VON WILLEBRAND FACTOR;

ARTHROPOD; ARTICLE; BLEEDING; BLOOD CLOTTING; CONTROLLED STUDY; DRUG CONFORMATION; DRUG EFFECT; DRUG ISOLATION; FEEDING BEHAVIOR; HEMOSTASIS; HOST PARASITE INTERACTION; MOLECULAR BIOLOGY; SKIN INJURY; STRUCTURE ACTIVITY RELATION; THROMBOCYTE AGGREGATION; TICK BITE; VACCINE PRODUCTION; VASOCONSTRICTION;

ANIMALS; HEMOSTASIS; MAMMALS; SALIVARY GLANDS; TICKS; VACCINES;

ACARI; ARTHROPODA;

EID: 0036219722     PISSN: 00471917     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (64)

1. Clinical spectrum of Glanzmann's thrombothenia
2. Generation and characterization of specific antibodies directed to the binding domain of adhesive molecules
3. Structure, function and evolutionary relationship of proteins containing a disintegrin domain
4. Clinical, biochemical, and molecular aspects of Glanzman's thrombathenia in humans and dogs
5. Tick saliva: Recent advances and implications for vector comptence
6. Tick salivary prostaglandins: Presence, origin and significance
7. Purification, partial characterization, cloning of nitric oxide-carrying heme proteins (nitrophorins) from salivary glands of the blood-sucking insect Rhodnius prolixus
8. The salivary gland-specific apyrase of the mosquito Aedes aegypti is a member of the 5′-nucleotidase family
9. Pharmacology of haematophagous arthropod saliva
10. The ATP receptor of rat mast cells
11. An inhibitor of collagen-stimulated platelet activation from the salivary glands of the Haementeria officianalis leech
12. Chronic treatment with P2-purigenic receptor agonists induces phenotypic modulation of the HL-60 and U-937 human myelogenous leukemia cell lines
13. Analyses of cDNA and recombinant protein for a potent vasoactive protein in saliva of blood-feeding black fly, Simulium vittatum
14. Naturally occurring mutations in glycoprotein Iba that result in defective ligand binding and sythensis of truncated protein
15. Nucleotide receptors: An emerging family of regulatory molecules in blood cells
16. Extracellular ATP triggers IL-1beta release by activating the purinergic P2Z receptor of human macrophages
17. Adenosine and adenine nucleotides are mitogenic for mouse thymocytes
18. Factors V and VII anticoagulant activities in the salivary glands of feeding Dermacentor andersoni ticks
19. Disintegrins: A family of integrin inhibitory proteins from the viper venoms
20. Isolation of a thrombin inhibitor from the tick Ixodes ricinus
21. Boophilus microplus anticoagulant protein: An antithrombin inhibitor isolated from the cattle tick saliva
22. Experimental hemostasis in normal dogs and dogs with congenital disorders of blood coagulation
23. The role of von Willebrand factor and fibrinogen in platelet aggregation under varying shear stress
24. Isolation and characterization of an anticoagulant present in the salivary glands of the bont-legged tick, Hyalomma analoticum
25. Cloning, nucleotide sequence and expression of the gene encoding factor Xa inhibitor from the salivary glands of the tick. Ornithodoros savignyi
26. The interaction of disagregin with the platelet fibrinogen receptor, glycoprotein IIb-IIIa
27. Disagregin is a fibrinogem receptor antagonist lacking the Ar-Gly-Asp sequence from the tick, Ornithodoros moubata
28. An inhibitor from the argasid tick Ornithodoros moubata of cell adhesion to collagen
29. Cloning of the cDNA and expression of moubatin, an inhibitor of platelet aggregation
30. Comparison of cutaneous hyperemia in cattle elicited by larvae of Boophilus microplus and by prostaglandins and other mediators
31. Biochemical insights derived from insect diversity
32. Molecular mechanisms of platelet aggregation
33. Purification and characterization of an anticoagulant from the salivary glands of the Ixodid tick, Rhipicephalus appendiculatus
34. Cloning and expression of ecto-5-nucleotidase from the cattle tick Boophilus microplus
35. Localisation and functional studies on the 5′ -nucleotidase of the cattle tick Boophilus microplus
36. Disaggregation of aggregated platelets by apyrase from the tick, Ornithodoros savinyi (Acari: Argarsidae)
37. Apyrase activity and platelet aggregation inhibitors in the tick Ornithodoros savinyi (Acari: Argarsidae)
38. Inhibition of mosquito salivary gland apyrase activity by the antibodies produced in mice immunized by bites of Anopheles stephensi mosquitoes
39. Ornatins: Potent glycoprotein IIb-IIIa antagonists and platelets aggregation inhibitors from the leech Placobdella ornata
40. Characterization of an 84 kDa protein inducing an immediate hypersensitivity reaction in rabbits sensitized to Haemaphysalis longicornis ticks
41. Issues in tick vaccine development; Identification and characterization of potential candidate vaccine antigens
42. Molecular characterization of a Haemaphysalis longicornis tick salivary gland associated29kilodalton protein and its vaccine effect against tick infestation in rabbits
43. Normal and abnormal haemostasis
44. ATP-induced activation of human B lymphocytes via P2-purinoceptors
45. Prostaglandin E2 in the salivary glands of the female tick, Amblyomma americanum (L.): Calcium mobilization and exocytosis
46. Role of saliva in blood-feeding by arthropods
47. Saliva of the soft tick, Ornithodoros moubata, contains anti-platelet and apyrase activities
48. Salivary glands of the sand fly phlebotomus papatasi contain pharmacologically active amounts of adenosine and 5′-AMP
49. Antihemostatic, antiinflamatory, and immunosuppressive properties of the saliva of a tick, Ixodes dammini
50. Purification and characterization of prolixin-S (nitrophorin-2), the salivary anticoagulant of the blood-sucking bug Rhodnius prolixus
51. Salivary gland physiology of blood-feeding arthropods
52. Characterization of the integrin specificities of disintegrins isolated from American pit viper venoms
53. Dercosin, a potent glycoprotein IIb-IIIa antagonist and platelet aggregation inhibitor from the leech Macrobdella decora
54. Glanzmann thrombothaenia: Intergrin alpha beta 3 deficiency
55. cDNA cloning, characterization and vaccine effect analysis of Haemaphysalis longicornis tick saliva proteins
56. Purification, cloning, and expression of an apyrase from the bed bug Cimex lectularius. A new type of nucleotide-binding enzyme
57. Crysoptin is a potent glycoprotein IIb/IIIa fibrinogen receptor antagonist present in salivary gland extracts of the deerfly
58. Variabilin, a novel RGD-containing antagonist of glycoprotein IIb-IIIa and platelet aggregation inhibitor from the hard tick Dermancentor variabilis
59. Isolation of an inhibitor selective for collagen-stimulated platelet aggregation from the soft tick, Ornithodoros moubata
60. Tick anticoagulant peptide (TAP) is a novel inhibitor of blood coagulation factor Xa
61. Purification and properties of a novel nucleotide-hydrolysing enzyme (5′-nucleotidase) from Boophilus microplus
62. The nucleotidase of Boophilus microplus and its relationship to enzymes from the rat and Escherichia coli
63. Prostaglandin E2-stimulated secretion of protein in the salivary glands of the lone star tick via a phosphoinositide signaling pathway
64. Identification and characterization of anticoagulant activities in the saliva of the lone star tick, Amblyomma americanum (L)