Interaction and activation of luteinizing hormone receptor

Indian Journal of Experimental Biology

Volumn 40, Issue 4, 2002, Pages 424-433

  Yong, Sang Song ^a   Yi, ChongSeoung ^a   Lee, ChangWoo ^a   Jeoung, MyungKun ^a   Ryu, KiSung ^a   Ji, Inhae ^a   Ji, Tae H ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; PROTEINS;

HORMONE RECEPTORS;

HORMONES;

EID: 0036217476     PISSN: 00195189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (56)

1. Structural features of mammalian gonadotropins
2. Glycoprotein hormones: Structure and function
3. The LH/hCG receptor
4. G protein-coupled receptors I: Diversity of receptor-ligand interactions
5. Initial and cyclic recruitment of ovarian follicles
6. Endocrinolog of human gestation
7. Molecular genetic, biochemical, and clinical implications of gonadotropin receptor mutations
8. Menstrual disorders and infertility caused by inactivating mutations of the luteinizing hormone receptor gene
9. A limited repertoire of mutations of the luteinizing hormone (LH) receptor gene in familial and sporadic patients with male LH-independent precocious puberty
10. Mutations and polymorphisms in gonadotropin genes
11. Carbohydrate and peptide structure of the alpha- and beta-subunits of human chorionic gonadotropin from normal and aberrant pregnancy and choriocarcinoma
12. Review: Gonadotropins and development of ovarian cancer
13. Cancer statistics, 1993
14. The dilemmas of prostate cancer
15. Menopause: The aging of multiple pacemakers
16. Why do postmenopausal women discontinue hormone replacement therapy?
17. The luteinizing hormone receptor
18. Structural and molecular studies of human chorionic gonadotropin and its receptor
19. Phtoaffinity labeling of the lutropin receptor with synthetic peptide for the carboxyl terminal of the human choriogonadotropin α subunit
20. Novel insights into the molecular mechanisms of human thyrotropin action: Structural, physiological, and therapeutic implications for the glycoprotein hormone family
21. Human follicle-stimulating hormone structure-activity relationships
22. The application of chemical crosslinking for studies on cell membranes and the identification of surface receptors
23. Radioiodination of a photoactivable heterobifunctional reagent
24. A novel approach to the identification of surface receptors: The use of photosensitive heterobifunctional cross-linking reagent
25. The domain structure of the choriogonadotropin receptor
26. Both a and b subunits of human choriogonadotropin photoaffinity label the hormone receptor
27. The alpha-subunit of human choriogonadotropin interacts with the exodomain of the luteinizing hormone/choriogonadotropin receptor
28. The beta-subunit of human choriogonadotropin interacts with the exodomain of the luteinizing hormone/choriogonadotropin receptor and changes its interaction with the alpha-subunit
29. Intronic nature of the rat luteinizing hormone receptor gene defines a soluble receptor subspecies with hormone binding activity
30. Extracellular domain of lutropin/choriogonadotropin receptor expressed in transfected cells binds choriogonadotropin with high affinity
31. Exons 1-10 of the rat LH receptor encode a high affinity hormone binding site and exon 11 encodes G-protein modulation and a potential second hormone binding site
32. Amino-terminal leucine-rich repeats in gonadotropin receptors determine hormone selectivity
33. Co-evolution of ligand-receptor pairs
34. Accessibility of rat and human follitropin receptor primary sequence (R265-S296) in situ
35. Reconstitution of a high-affinity functional lutropin receptor by coexpression of its extracellular and membrane domains
36. Activation of membrane receptors
37. Receptor binding dependent structural changes in human choriogonadotropin: Photochemical inter-subunit crosslinking
38. Exoloop 3 of the LH/CG receptor: Lys583 is essential and irreplaceable for hCG dependent receptor activation but not for high affinity hCG binding
39. The luteinizing hormone/human choriogonadotropin receptor has distinct transmembrane conductors for cAMP and inositol phosphate signals
40. Modulation of high affinity hormone binding: Human choriogonadotropin binding to the exodomain of the receptor is influenced by exoloop 2 of the receptor
41. High affinity hormone binding to the extracellular N-terminal exodomain of the follicle-stimulating hormone receptor is critically modulated by exoloop 3
42. Derivation of functional antagonists using N-terminal extracellular domain of gonadotropin and thyrotropin receptors
43. Identification of ionizable amino acid residues on the extracellular domain of the lutropin receptor involved in ligand binding
44. Identification of hormone-binding regions of the luteinizing hormone/human chorionic gonadotropin receptor using synthetic peptides
45. Lutropin-choriogonadotropin receptor: An unusual member of the G protein-coupled receptor family
46. Structure of the luteinizing hormone receptor gene and multiple exons of the coding sequence
47. The leucine-rich repeat: A versatile binding motif
48. A structural basis of the interactions between leucine-rich repeats and protein ligands
49. Molecular recognition of human angiogenin by placental ribonuclease inhibitor - An X-ray crystallographic study at 2 0 A resolution
50. Structural predictions for the ligand-binding region of glycoprotein hormone receptors and the nature of hormone-receptor interactions
51. Determination of residues important in hormone binding to the extracellular domain of the luteinizing hormone/chorionic gonadotropin receptor by site-directed mutagenesis and modelling
52. Model of human chorionic gonadotropin and lutropin receptor interaction that explains signal transduction of the glycoprotein hormones
53. The amino-terminal region of the lutropin/choriogonadotropin receptor contacts both subunits of human choriogonadotropin: I mutational analysis
54. The amino-terminal region of the lutropin/choriogonadotropin receptor contacts both subunits of human choriogonadotropin: II photoaffinity labelling
55. The glycoprotein hormones: Recent studies of structure-function relationships
56. Transmembrane regions v and vi of the human luteinizing hormone receptor are required for constitutive activation by a mutation in the third intracellular loop