Characterization of a novel missense mutation E637K in the pore-S6 loop of HERG in a patient with long QT syndrome

Cardiovascular Research

Volumn 54, Issue 1, 2002, Pages 67-76

  Hayashi, Kenshi ^a   Shimizu, Masami ^a   Ino, Hidekazu ^a   Yamaguchi, Masato ^a   Mabuchi, Hiroshi ^a   Hoshi, Naoto ^a   Higashida, Haruhiro ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

Arrhythmia (mechanisms); K channel; Long QT syndrome

Indexed keywords

AMINO ACID; GLUTAMIC ACID; LYSINE; POTASSIUM ION; PROTEIN; PROTEIN HERG; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; GENE EXPRESSION; GENETIC ANALYSIS; HUMAN; KINETICS; LONG QT SYNDROME; MISSENSE MUTATION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; STEADY STATE; SYNCOPE; WILD TYPE; XENOPUS;

ADULT; ANALYSIS OF VARIANCE; ANIMALS; CATION TRANSPORT PROTEINS; CELLS, CULTURED; DNA-BINDING PROTEINS; ETHER-A-GO-GO POTASSIUM CHANNELS; FEMALE; HUMANS; LONG QT SYNDROME; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; OOCYTES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; SYNCOPE; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; XENOPUS;

EID: 0036217325     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(02)00240-7     Document Type: Article

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