A molecular link between gene-specific and chromosome-wide transcriptional repression

Genes and Development

Volumn 16, Issue 7, 2002, Pages 796-805

  Chu, Diana S ^a   Dawes, Heather E ^a,b   Lieb, Jason D ^a,c   Chan, Raymond C ^a   Kuo, Annie F ^a   Meyer, Barbara J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Cell Press   (United States)

^c STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

C. elegans; Chromatin; Dosage compensation; Sex determination; Transcriptional repression

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SDC 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; GENE; GENE DOSAGE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE LOCATION; GENE REPRESSION; GENE SEQUENCE; GENE SILENCING; HER 1 GENE; IN VIVO STUDY; MALE; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; REGULATORY MECHANISM; SEX DIFFERENTIATION; TRANSCRIPTION REGULATION; TRUE HERMAPHRODITISM; X CHROMOSOME;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CHROMATIN; CHROMOSOMES; DNA; DOSAGE COMPENSATION, GENETIC; FEMALE; HELMINTH PROTEINS; MALE; MICROSCOPY, FLUORESCENCE; MODELS, GENETIC; PHENOTYPE; PRECIPITIN TESTS; PROTEIN BINDING; REPRESSOR PROTEINS; SEX DETERMINATION (GENETICS); TRANSCRIPTION, GENETIC; X CHROMOSOME;

ANIMALIA; CAENORHABDITIS; CAENORHABDITIS ELEGANS;

EID: 0036212008     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.972702     Document Type: Article

References (31)

1. Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae
2. The nuclear hormone receptor SEX-1 is an X-chromosome signal that determines nematode sex
3. Sex-specific assembly of a dosage compensation complex on the nematode X chromosome
4. SDC-3 coordinates the assembly of a dosage compensation complex on the nematode X chromosome
5. Dosage compensation proteins targeted to X chromosomes by a determinant of hermaphrodite fate
6. Feedback control of sex determination by dosage compensation revealed through Caenorhabditis elegans sdc-3 mutations
7. Mapping DNA interaction sites of chromosomal proteins using immunoprecipitation and polymerase chain reaction
8. Chromosome cohesion, condensation, and separation
9. Primary sex determination in the nematode C. elegans
10. Independent domains of the sdc-3 protein control sex determination and dosage compensation in C. elegans
11. Mitotic chromosome condensation
12. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
13. Evidence for multiple promoter elements orchestrating male-specific regulation of the her-1 gene in Caenorhabditis elegans
14. DPY-26, a link between dosage compensation and meiotic chromosome segregation in the nematode
15. MIX-1: An essential component of the C. elegans mitotic machinery executes X chromosome dosage compensation
16. The Caenorhabditis elegans dosage compensation machinery is recruited to X chromosome DNA attached to an autosome
17. Sex in the worm: Counting and compensating X-chromosome dose
18. xol-l: A gene that controls the male modes of both sex determination and X chromosome dosage compensation in C. elegans
19. Common themes in mechanisms of gene silencing
20. Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1
21. Rb targets histone H3 methylation and HP1 to promoter
22. Early aspects of Caenorhabditis elegans sex determination and dosage compensation are regulated by a zinc-finger protein
23. The Caenorhabditis elegans gene sdc-2 controls sex determination and dosage compensation in XX animals
24. Molecular characterization of the her-1 gene suggests a direct role in cell signaling during Caenorhabditis elegans sex determination
25. Sequenced alleles of the Caenorhabditis elegans sex-determining gene her-1 include a novel class of conditional promoter mutations
26. Genes that implement the hermaphrodite mode of dosage compensation in Caenorhabditis elegans
27. GFP tagging of budding yeast chromosomes reveals that protein-protein interactions can mediate sister chromatid cohesion
28. A novel dominant transformer allele of the sex-determining gene her-1 of Caenorhabditis elegans
29. Sex-specific transcriptional regulation of the C. elegans sex-determining gene her-1
30. The role of sdc-1 in the sex determination and dosage compensation decisions in Caenorhabditis elegans
31. Interpretation of X chromosome dose at Sex-lethal requires non-E-box sites for the basic helix-loop-helix proteins SISB and daughterless