Lavage and nipple aspiration of breast ductal fluids: A source of biomarkers for environmental mutagenesis

Environmental and Molecular Mutagenesis

Volumn 39, Issue 2-3, 2002, Pages 127-133

  Klein, Pamela M ^a   Lawrence, Julia A ^b  

^a GENENTECH INC   (United States)

^b LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

Author keywords

Biomarkers; Breast cancer; Ductal lavage; Environmental mutagens; Nipple aspiration fluid

Indexed keywords

BIOLOGICAL MARKER; CARCINOEMBRYONIC ANTIGEN; ENVIRONMENTAL MUTAGEN; PROSTATE SPECIFIC ANTIGEN;

ASPIRATION; BREAST CANCER; BREAST CARCINOGENESIS; BREAST DUCT; CONFERENCE PAPER; DIAGNOSTIC VALUE; DISEASE MARKER; ENVIRONMENTAL FACTOR; GEL ELECTROPHORESIS; GENE AMPLIFICATION; HUMAN; LAVAGE; POLYMERASE CHAIN REACTION; QUANTITATIVE ANALYSIS;

ADULT; AGED; BIOLOGICAL MARKERS; BIOPSY, NEEDLE; BODY FLUIDS; BREAST NEOPLASMS; CARCINOGENS, ENVIRONMENTAL; DNA, NEOPLASM; ENVIRONMENTAL EXPOSURE; FEMALE; HUMANS; IRRIGATION; MIDDLE AGED; NIPPLES;

SALMONELLA;

EID: 0036205816     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/em.10061     Document Type: Conference Paper

References (45)

1. Breast adipose tissue concentrations of polychlorinated biphenyls and other organochlorines and breast cancer risk
2. Metabolic activation and DNA binding of food mutagens and other environmental carcinogens in human mammary epithelial cells
3. Significance of nipple discharge: Clinical pattern in the selection of cases for cytologic examination
4. Genetic polymorphisms and risk of breast cancer
5. BRCA1 and BRCA2 gene mutations and risk of breast cancer. Public health perspectives
6. Cytodiagnosis of nipple discharge: A study of 602 samples from 484 cases
7. Pilot study of free and conjugated urinary mutagenicity during the consumption of pan-fried meats: Possible modulation by cruciferous vegetables, glutathione S-transferase-M1, and N-acetytransferase-2
8. Risk and aggressiveness of breast cancer in relation to plasma organochlorine concentrations
9. Detection of pre-malignant and malignant breast cells by ductal lavage
10. Association between functional genetic polymorphisms of human sulfotransferases 1A1 and 1A2
11. Detection of breast cancer cells in ductal lavage fluid by methylation-specific PCR
12. Biomarker and cytologic abnormalities in women at high and low risk for breast cancer
13. Carcinoembryonic antigen in breast nipple aspirate fluid
14. Projecting individualized probabilities of developing breast cancer for white females who are being examined annually
15. Breast fluid cholesterol and cholesterol epoxides: Relationship to breast cancer risk factors and other characteristics
16. Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
17. The role of peroxidase-catalyzed activation of aromatic amines in breast cancer
18. Cellular composition of the nipple aspirate specimen of breast fluid. I. The benign cells
19. Biomarker assays in nipple aspirate fluid
20. The distribution of carcinoembryonic antigen in breast carcinoma. Diagnostic and prognostic implications
21. 1,1-Dichloro-2,2-bis(p-chlorophenyl)ethylene and polychlorinated biphenyls and breast cancer: Combined analysis of five U.S. studies
22. Phase I clinical trial of ali-tretinoin and tamoxifen in breast cancer patients: Toxicity, pharmacokinetic, and biomarker evaluations
23. The association of dietary fat with the ability to obtain breast fluid by nipple aspiration
24. Biochemical and ultrastructural features of human milk and nipple aspirate fluids
25. Genotoxicity of human mammary lipid
26. Anatomic markers of human premalignancy and risk of breast cancer
27. Premalignant conditions and markers of elevated risk in the breast and their management
28. Exfoliative cytology of the human mammary gland and it value in the diagnosis of cancer and other diseases of the breast
29. Nipple aspirate fluid in epidemiologic studies of breast disease
30. Studies on the epidemiology and natural history of benign breast disease and breast cancer using nipple aspirate fluid
31. Mutagenic activity in nipple aspirates of human breast fluid
32. + ratio, and coloration
33. Pilot studies on the p53 gene in nipple aspirate fluid from patients with breast cancer
34. Identification of the major protein components in breast secretions from women with benign and malignant breast diseases
35. Cytologic evaluation of breast fluid in the detection of breast disease
36. Prostate-specific antigen levels in nipple aspirate fluid correlate with breast cancer risk
37. Nipple aspirate fluid: A promising non-invasive method to identify cellular markers of breast cancer risk
38. The mutagenic activity of human breast secretions
39. Breast cancer risk in relation to adipose concentrations of organochlorine pesticides and polychlorinated biphenyls in Long Island, New York
40. Nipple discharge cytology in mass screening for breast cancer
41. N-Acetyltransferases, sulfotransferases and heterocyclic amine activation in the breast
42. Risk of breast cancer and organochlorine exposure
43. Breast cancer incidence in women with abnormal cytology in nipple aspirates of breast fluid
44. Nipple fluid carcinoembryonic antigen and prostate-specific antigen in cancer-bearing and tumor-free breasts
45. Risk of breast cancer associated with serum polychlorinated biphenyls and 1,1-dichloro-2,2′-bis(p-chlorophenyl)ethylene