Toxin-induced calcium oscillations: A novel strategy to affect gene regulation in target cells

International Journal of Medical Microbiology

Volumn 291, Issue 6-7, 2001, Pages 511-515

  Söderblom, Tomas ^a   Laestadius, A ^b   Oxhamre, Camilla ^a   Aperia, Anita ^b   Richter Dahlfors, Agneta ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

E. coli haemolysin; Gene expression; Innate immunity; Intracellular calcium oscillations

Indexed keywords

ESCHERICHIA COLI;

EID: 0036196921     PISSN: 14384221     EISSN: None     Source Type: Journal    
DOI: 10.1078/1438-4221-00160     Document Type: Article

References (27)

1. A pore-forming toxin interacts with a GPI-anchored protein and causes vacuolation of the endoplasmic reticulum
2. Induction of innate immune responses by Escherichia coli and purified lipopolysaccharide correlate with organ- and cell-specific expression of Toll-like receptors within the urinary tract
3. NF-κB: Ten years after
4. Calcium - A life and death signal
5. Escherichia coli hemolysin may damage target cell membranes by generating transmembrane pores
6. Calcium is required for binding of Escherichia coli hemolysin (HlyA) to erythrocyte membranes
7. 2+ response amplitude and duration
8. Calcium oscillations increase the efficency and specificity of gene expression
9. Alterations of amino acid repeats in the Escherichia coli hemolysin affect cytolytic activity and secretion
10. LPS induction of gene expression in human monocytes
11. In vivo dynamics of type 1 fimbria regulation in uropathogenic Escherichia coli during experimental urinary tract infection
12. Role of the ceramide-signaling pathway in cytokine responses to p-fimbriated Escherichia coli
13. Activation of Escherichia coli prohemolysin to the mature toxin by acyl carrier protein-dependent fatty acylation
14. Interleukin-6 and interleukin-8 in serum and urine in patients with acute pyelonephritis in relation to bacterial-virulence-associated traits and renal function
15. Analysis of the in vivo activation of hemolysin (HlyA) from Escherichia coli
16. 2+-dependent binding to erythrocytes
17. Mutations affecting pore formation by haemolysin from Escherichia coli
18. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
19. Induction and evasion of host defences by type 1-piliated uropathogenic Escherichia coli
20. Bacterial polysaccharide synthesis and gene nomenclature
21. Murine salmonellosis studied by confocal microscopy: Salmonella typhimurium resides intracellularly inside macrophages and exerts a cytotoxic effect on phagocytes in vivo
22. Interaction of Escherichia coli hemolysin with biological membranes: A study using cysteine scanning mutagenesis
23. Acylation of Escherichia coli hemolysin: A unique protein lipidation mechanism underlying toxin function
24. Fatty acylations of two internal lysine residues required for the toxic activity of Escherichia coli hemolysin
25. Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
26. Bacterial protein toxins - General conclusions
27. 2+ oscillations in renal epithelial cells