-
1
-
-
0028501442
-
The ups and downs of T cell costimulation
-
Jenkins MK: The ups and downs of T cell costimulation. Immunity 1994, 1:443-446.
-
(1994)
Immunity
, vol.1
, pp. 443-446
-
-
Jenkins, M.K.1
-
2
-
-
0028178873
-
Signals and signs for lymphocyte responses
-
Janeway CJ, Bottomly K: Signals and signs for lymphocyte responses. Cell 1994, 76:275-285.
-
(1994)
Cell
, vol.76
, pp. 275-285
-
-
Janeway, C.J.1
Bottomly, K.2
-
4
-
-
0029058111
-
T helper cell differentiation in immune response
-
Reiner SL, Seder RA: T helper cell differentiation in immune response. Curr Opin Immunol 1995, 7:360-366.
-
(1995)
Curr Opin Immunol
, vol.7
, pp. 360-366
-
-
Reiner, S.L.1
Seder, R.A.2
-
5
-
-
0027299866
-
Homing of naive, memory and effector lymphocytes
-
Mackay CR: Homing of naive, memory and effector lymphocytes. Curr Opin Immunol 1993, 5:423-427.
-
(1993)
Curr Opin Immunol
, vol.5
, pp. 423-427
-
-
Mackay, C.R.1
-
6
-
-
0028085152
-
T and B memory cells
-
Sprent J: T and B memory cells. Cell 1994, 76:315-322.
-
(1994)
Cell
, vol.76
, pp. 315-322
-
-
Sprent, J.1
-
7
-
-
0028340252
-
Regulation of immunological memory
-
Gray D: Regulation of immunological memory. Curr Opin Immunol 1994, 6:425-430.
-
(1994)
Curr Opin Immunol
, vol.6
, pp. 425-430
-
-
Gray, D.1
-
8
-
-
0028466130
-
Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo
-
Kearney ER, Pape KA, Loh DY, Jenkins MK: Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity 1994, 1:327-339. An elegant use of TCR transgenic T cells in an adoptive transfer model defines distinct physical outcomes for the progression of antigen-specific T-cell immunity versus the induction of tolerance.
-
(1994)
Immunity
, vol.1
, pp. 327-339
-
-
Kearney, E.R.1
Pape, K.A.2
Loh, D.Y.3
Jenkins, M.K.4
-
10
-
-
0027964431
-
The B7 and CD28 receptor families
-
June CH, Bluestone JA, Nadler LM, Thompson CB: The B7 and CD28 receptor families. Immunol Today 1994, 15:321-331.
-
(1994)
Immunol Today
, vol.15
, pp. 321-331
-
-
June, C.H.1
Bluestone, J.A.2
Nadler, L.M.3
Thompson, C.B.4
-
12
-
-
0029120245
-
CD2B and CTLA-4 have opposing effects on the response of T cells to stimulation
-
Krummel MF, Allison JP: CD2B and CTLA-4 have opposing effects on the response of T cells to stimulation. J Exp Med 1995, 182:459-465.
-
(1995)
J Exp Med
, vol.182
, pp. 459-465
-
-
Krummel, M.F.1
Allison, J.P.2
-
13
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in CTLA-4
-
Waterhouse P, Penninger JM, Timms E, Wakeman A, Shahinian A, Lee KP, Thompson CB, Griesser H, Mak TW: Lymphoproliferative disorders with early lethality in mice deficient in CTLA-4. Science 1995, 270:985-988. A dramatic phenotype highlights an important role for CTLA-4 in the regulation of the developing immune response. The lymphoproliferative disorder implicates a defect in the contraction phase of an effector response and an important role for CTLA-4 in controlling lymphocyte homeostasis.
-
(1995)
Science
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
Wakeman, A.4
Shahinian, A.5
Lee, K.P.6
Thompson, C.B.7
Griesser, H.8
Mak, T.W.9
-
14
-
-
0029097387
-
Activated T cells can induce high levels of CTLA-4 expression on B cells
-
Kuiper HM, Brouwer M, Linsley PS, van LR: Activated T cells can induce high levels of CTLA-4 expression on B cells. J Immunol 1995, 155:1776-1783. Describes a role for CTLA-4 in the cascade of TB cross-talk.
-
(1995)
J Immunol
, vol.155
, pp. 1776-1783
-
-
Kuiper, H.M.1
Brouwer, M.2
Linsley, P.S.3
Van, L.R.4
-
15
-
-
0028949152
-
B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy
-
Kuchroo VK, Das MP, Brown JA, Ranger AM, Zamvil SS, Sobel RA, Weiner HL, Nabavi N, Glimcher LH: B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell 1995, 80:707-718. This paper highlights the importance of co-stimulatory signals transmitted through CTLA-4 and CD28 on the profile of cytokine produced by antigen-activated T cells, and provides a mechanism for the modulation of autoimmune disease.
-
(1995)
Cell
, vol.80
, pp. 707-718
-
-
Kuchroo, V.K.1
Das, M.P.2
Brown, J.A.3
Ranger, A.M.4
Zamvil, S.S.5
Sobel, R.A.6
Weiner, H.L.7
Nabavi, N.8
Glimcher, L.H.9
-
17
-
-
0028790434
-
CD40 ligand-transduced costimulation of T cells in the development of helper function
-
••] highlight the importance of not only giving but also receiving signals through CD40L for the completion of effective immunity in vivo. Soluble CD40 restores the signals to initiate germinal center formation and isotype switch in animals lacking CD40.
-
(1995)
Nature
, vol.378
, pp. 620-623
-
-
Van Essen, D.1
Kikutani, H.2
Gray, D.3
-
18
-
-
0028064578
-
Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire
-
Cyster JG, Hartley SB, Goodnow CC: Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire. Nature 1994, 371:389-395.
-
(1994)
Nature
, vol.371
, pp. 389-395
-
-
Cyster, J.G.1
Hartley, S.B.2
Goodnow, C.C.3
-
19
-
-
0029014435
-
Antigen-induced B-cell death and elimination during germinal-centre immune responses
-
Shokat KM, Goodnow CC: Antigen-induced B-cell death and elimination during germinal-centre immune responses. Nature 1995, 375:334-338.
-
(1995)
Nature
, vol.375
, pp. 334-338
-
-
Shokat, K.M.1
Goodnow, C.C.2
-
20
-
-
0029076561
-
+ T cells
-
+ T cells. Nature 1995, 376:181-184. An adoptive transfer model using TCR transgenic T cells and Ig transgenic B cells reveals a specific T-cell-dependent means of eliminating autoreactive B cells in vivo that requires CD95.
-
(1995)
Nature
, vol.376
, pp. 181-184
-
-
Rathmell, J.C.1
Cooke, M.P.2
Ho, W.Y.3
Grein, J.4
Townsend, S.E.5
Davis, M.M.6
Goodnow, C.C.7
-
21
-
-
0028485743
-
The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice
-
Singer GG, Abbas AK: The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. Immunity 1994, 1:365-371. This paper provides evidence for the role of CD95 in the deletion of mature T cells following antigen-driven clonal expansion in the periphery.
-
(1994)
Immunity
, vol.1
, pp. 365-371
-
-
Singer, G.G.1
Abbas, A.K.2
-
22
-
-
0026502380
-
Mapping T-cell receptor-peptide contacts by variant peptide immunization of single-chain transgenics
-
Jorgensen JL, Esser U, Fazekas De St Groth B, Reay PA, Davis MM: Mapping T-cell receptor-peptide contacts by variant peptide immunization of single-chain transgenics. Nature 1992, 355:224-230.
-
(1992)
Nature
, vol.355
, pp. 224-230
-
-
Jorgensen, J.L.1
Esser, U.2
Fazekas De St Groth, B.3
Reay, P.A.4
Davis, M.M.5
-
23
-
-
0029038051
-
T-cell receptor V-region usage and antigen specificity. the cytochrome c model system
-
Davis MM, McHeyzer-Williams MG, Chien YH: T-cell receptor V-region usage and antigen specificity. The cytochrome c model system. Ann NY Acad Sci 1995, 756:1-11.
-
(1995)
Ann NY Acad Sci
, vol.756
, pp. 1-11
-
-
Davis, M.M.1
McHeyzer-Williams, M.G.2
Chien, Y.H.3
-
24
-
-
0342284524
-
Enumeration and characterization of memory cells in the Th compartment
-
in press
-
McHeyzer-Williams MG, Altman JD, Davis MM: Enumeration and characterization of memory cells in the Th compartment. Immunol Rev 1996, in press. Multiparameter flow cytometry is used to compare the kinetics of an antigen-specific T-cell response in single-chain and double-chain TCR transgenic animals with that in a normal animal.
-
(1996)
Immunol Rev
-
-
McHeyzer-Williams, M.G.1
Altman, J.D.2
Davis, M.M.3
-
25
-
-
0029039968
-
Role of T helper cell precursor frequency on vesicular stomatitis virus neutralizing antibody responses in a T cell receptor beta chain transgenic mouse
-
Freer G, Burkhart C, Rulicke T, Ghelardi E, Rohrer UH, Pircher H, Zinkernagel RM, Hengartner H: Role of T helper cell precursor frequency on vesicular stomatitis virus neutralizing antibody responses in a T cell receptor beta chain transgenic mouse. Eur J Immunol 1995, 25:1410-1416.
-
(1995)
Eur J Immunol
, vol.25
, pp. 1410-1416
-
-
Freer, G.1
Burkhart, C.2
Rulicke, T.3
Ghelardi, E.4
Rohrer, U.H.5
Pircher, H.6
Zinkernagel, R.M.7
Hengartner, H.8
-
27
-
-
0026648380
-
Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system
-
USA
-
Hsieh CS, Heimberger AB, Gold JS, O'Garra A, Murphy KM: Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system. Proc Natl Acad Sci USA 1992, 89:6065-6069.
-
(1992)
Proc Natl Acad Sci
, vol.89
, pp. 6065-6069
-
-
Hsieh, C.S.1
Heimberger, A.B.2
Gold, J.S.3
O'Garra, A.4
Murphy, K.M.5
-
28
-
-
0027517824
-
Activation and differentiation requirements of primary T cells in vitro
-
USA
-
Sagerstrom CG, Kerr EM, Allison JP, Davis MM: Activation and differentiation requirements of primary T cells in vitro. Proc Natl Acad Sci USA 1993, 90:8987-8991.
-
(1993)
Proc Natl Acad Sci
, vol.90
, pp. 8987-8991
-
-
Sagerstrom, C.G.1
Kerr, E.M.2
Allison, J.P.3
Davis, M.M.4
-
29
-
-
0028361047
-
Role of cytokines in determining T-lymphocyte function
-
O'Garra A, Murphy K: Role of cytokines in determining T-lymphocyte function. Curr Opin Immunol 1994, 6:458-466.
-
(1994)
Curr Opin Immunol
, vol.6
, pp. 458-466
-
-
O'Garra, A.1
Murphy, K.2
-
30
-
-
0028518985
-
Generation and in vivo persistence of polarized Th1 and Th2 memory cells
-
Swain SL: Generation and in vivo persistence of polarized Th1 and Th2 memory cells. Immunity 1994, 1:543-552. An analysis of antigen-specific clonal stability in vivo using an adoptive-transfer approach coupled to antigen-specific manipulation in vitro. These data provide important clues to the nature and development of T-cell memory.
-
(1994)
Immunity
, vol.1
, pp. 543-552
-
-
Swain, S.L.1
-
31
-
-
0028906593
-
T cell genetic background determines default T helper phenotype development in vitro
-
Hsieh CS, Macatonia SE, O'Garra A, Murphy KM: T cell genetic background determines default T helper phenotype development in vitro. J Exp Med 1995, 181:713-721.
-
(1995)
J Exp Med
, vol.181
, pp. 713-721
-
-
Hsieh, C.S.1
Macatonia, S.E.2
O'Garra, A.3
Murphy, K.M.4
-
32
-
-
0029037210
-
Serial triggering of many T-cell receptors by a few peptide-MHC complexes
-
Valitutti S, Muller S, Cella M, Padovan E, Lanzavecchia A: Serial triggering of many T-cell receptors by a few peptide-MHC complexes. Nature 1995, 375:148-151. A study on the stoichiometry of TCR-MHC/peptide interactions and their functional outcomes in vitro. A single complex can serially trigger up to 200 TCRs over a 24 h period of culture.
-
(1995)
Nature
, vol.375
, pp. 148-151
-
-
Valitutti, S.1
Muller, S.2
Cella, M.3
Padovan, E.4
Lanzavecchia, A.5
-
33
-
-
0028589333
-
Kinetics of T-cell receptor binding to peptide/I-Ek complexes: Correlation of the dissociation rate with T-cell responsiveness
-
USA
-
Matsui K, Boniface JJ, Steffner P, Reay PA, Davis MM: Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness. Proc Natl Acad Sci USA 1994, 91:12862-12866.
-
(1994)
Proc Natl Acad Sci
, vol.91
, pp. 12862-12866
-
-
Matsui, K.1
Boniface, J.J.2
Steffner, P.3
Reay, P.A.4
Davis, M.M.5
-
34
-
-
0028120414
-
T cell receptor-MHC class I peptide interactions: Affintly, kinetics, and specificity
-
Corr M, Slantez AE, Boyd LF, Jelonek MT, Khilko BK, Al-Ramadi YS, Maher SE, Bothwell ALM, Margulies DH: T cell receptor-MHC class I peptide interactions: affintly, kinetics, and specificity. Science 1994, 265:946-949.
-
(1994)
Science
, vol.265
, pp. 946-949
-
-
Corr, M.1
Slantez, A.E.2
Boyd, L.F.3
Jelonek, M.T.4
Khilko, B.K.5
Al-Ramadi, Y.S.6
Maher, S.E.7
Bothwell, A.L.M.8
Margulies, D.H.9
-
38
-
-
0029037163
-
+ T cells
-
+ T cells. J Immunol 1995, 154:4915-4923.
-
(1995)
J Immunol
, vol.154
, pp. 4915-4923
-
-
Constant, S.1
Sant'Angelo, D.2
Pasqualini, T.3
Taylor, T.4
Levin, D.5
Flavell, R.6
Bottomly, K.7
-
39
-
-
0029091255
-
Successful T cell priming in B cell-deficient mice
-
Epstein MM, Di RF, Jankovic D, Sher A, Matzinger P: Successful T cell priming in B cell-deficient mice. J Exp Med 1995, 182:915-922.
-
(1995)
J Exp Med
, vol.182
, pp. 915-922
-
-
Epstein, M.M.1
Di, R.F.2
Jankovic, D.3
Sher, A.4
Matzinger, P.5
-
41
-
-
0028982517
-
Th1 and Th2 subsets: Paradigms lost?
-
Kelso A: Th1 and Th2 subsets: paradigms lost? Immunol Today 1995, 16:374-379. A cogent argument for re-thinking the Th1/Th2 paradigm for Th-cell development.
-
(1995)
Immunol Today
, vol.16
, pp. 374-379
-
-
Kelso, A.1
-
42
-
-
0029148642
-
Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry
-
Picker LJ, Singh MK, Zdraveski Z, Treer JR, Waldrop SL, Bergstresser PR, Maino VC: Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry. Blood 1995, 86:1408-1419.
-
(1995)
Blood
, vol.86
, pp. 1408-1419
-
-
Picker, L.J.1
Singh, M.K.2
Zdraveski, Z.3
Treer, J.R.4
Waldrop, S.L.5
Bergstresser, P.R.6
Maino, V.C.7
-
44
-
-
0026793582
-
Molecular detection and in vivo analysis of the specific T cell response to a protein antigen
-
Cochet M, Pannetier C, Regnault A, Darche S, Leclerc C, Kourilsky P: Molecular detection and in vivo analysis of the specific T cell response to a protein antigen. Eur J Immunol 1992, 22:2639-2647.
-
(1992)
Eur J Immunol
, vol.22
, pp. 2639-2647
-
-
Cochet, M.1
Pannetier, C.2
Regnault, A.3
Darche, S.4
Leclerc, C.5
Kourilsky, P.6
-
45
-
-
0028169415
-
Public and private V beta T cell receptor repertoires against hen egg white lysozyme (HEL) in nontransgenic versus HEL transgenic mice
-
Cibotti R, Cabaniols JP, Pannetier C, Delarbre C, Vergnon I, Kanellopoulos JM Kourilsky P: Public and private V beta T cell receptor repertoires against hen egg white lysozyme (HEL) in nontransgenic versus HEL transgenic mice. J Exp Med 1994, 180:861-872. This paper describes the application of a very useful PCR-based technology for identifying clonal restriction in the lymphocyte repertoire. TCR repertoires to self versus non-self peptides are examined.
-
(1994)
J Exp Med
, vol.180
, pp. 861-872
-
-
Cibotti, R.1
Cabaniols, J.P.2
Pannetier, C.3
Delarbre, C.4
Vergnon, I.5
Kanellopoulos, J.M.6
Kourilsky, P.7
-
46
-
-
0028138536
-
+ T cell population bearing a distinctive beta chain in MRL Ipr/Ipr mice suggests a role for the fas protein in peripheral T cell selection
-
+ T cell population bearing a distinctive beta chain in MRL Ipr/Ipr mice suggests a role for the fas protein in peripheral T cell selection. Eur J Immunol 1994, 24:2761-2766. An approach similar to that used in [44] provides evidence for restricted clonal expansion in the complex backdrop of MRL Ipr/Ipr mice.
-
(1994)
Eur J Immunol
, vol.24
, pp. 2761-2766
-
-
Musette, P.1
Pannetier, C.2
Gachelin, G.3
Kourilsky, P.4
-
47
-
-
0027943847
-
In vivo T-cell clonal amplification at time of acute graft-versus-host disease
-
Dietrich PY, Caignard A, Lim A, Chung V, Pico JL, Pannetier C, Kourilsky P, Hercend T, Even J, Triebel F: In vivo T-cell clonal amplification at time of acute graft-versus-host disease. Blood 1994, 84:2815-2820.
-
(1994)
Blood
, vol.84
, pp. 2815-2820
-
-
Dietrich, P.Y.1
Caignard, A.2
Lim, A.3
Chung, V.4
Pico, J.L.5
Pannetier, C.6
Kourilsky, P.7
Hercend, T.8
Even, J.9
Triebel, F.10
-
48
-
-
0027412016
-
Oligoclonal expansion of major histocompatibility complex class I-restricted cytolytic T lymphocytes during a primary immune response in vivo: Direct monitoring by flow cytometry and polymerase chain reaction
-
MacDonald HR, Casanova JL, Maryanski JL, Cerottini JC: Oligoclonal expansion of major histocompatibility complex class I-restricted cytolytic T lymphocytes during a primary immune response in vivo: direct monitoring by flow cytometry and polymerase chain reaction. J Exp Med 1993, 177:1487-1492
-
(1993)
J Exp Med
, vol.177
, pp. 1487-1492
-
-
MacDonald, H.R.1
Casanova, J.L.2
Maryanski, J.L.3
Cerottini, J.C.4
-
50
-
-
0027339408
-
TH1 and TH2 cell antigen receptors in experimental leishmaniasis
-
Reiner SL, Wang ZE, Hatam F, Scott P, Locksley RM: TH1 and TH2 cell antigen receptors in experimental leishmaniasis, Science 1993, 259:1457-1460.
-
(1993)
Science
, vol.259
, pp. 1457-1460
-
-
Reiner, S.L.1
Wang, Z.E.2
Hatam, F.3
Scott, P.4
Locksley, R.M.5
-
51
-
-
0028927653
-
Antigen-specific development of primary and memory T cells in vivo
-
McHeyzer-Williams MG, Davis MM: Antigen-specific development of primary and memory T cells in vivo. Science 1995, 268:106-111. Direct molecular and cellular analysis of an antigen-specific primary and memory T-cell response in normal mice. Clonal expansion and contraction are quantitatively monitored using single-cell repertoire analysis, providing evidence for clonal maturation in vivo.
-
(1995)
Science
, vol.268
, pp. 106-111
-
-
McHeyzer-Williams, M.G.1
Davis, M.M.2
-
52
-
-
0030020130
-
Single-cell PCR analysis of TCR repertoire selected by antigen in vivo: A high magnitude CD8 response is comprised of very few clones
-
Maryanski JL, Jongeneel CV, Bucher P, Casanova J-L, Walker PR: Single-cell PCR analysis of TCR repertoire selected by antigen in vivo: a high magnitude CD8 response is comprised of very few clones. Immunity 1996, 4:47-55. Single-cell PCR analysis of a dominant CTL response where the same animal can be followed through multiple rounds of antigenic exposure shows no apparent change in the TCR repertoire.
-
(1996)
Immunity
, vol.4
, pp. 47-55
-
-
Maryanski, J.L.1
Jongeneel, C.V.2
Bucher, P.3
Casanova, J.-L.4
Walker, P.R.5
-
53
-
-
0027960893
-
Locus-specific somatic hypermutation in germinal centre T cells
-
Zheng B, Xue W, Kelsoe G: Locus-specific somatic hypermutation in germinal centre T cells. Nature 1994, 372:556-559. Describes a powerful approach to the analysis of antigen-specific immunity in vivo, involving microdissection of histologically defined subpopulations followed by gene amplification and sequence analysis of particular TCR.
-
(1994)
Nature
, vol.372
, pp. 556-559
-
-
Zheng, B.1
Xue, W.2
Kelsoe, G.3
-
54
-
-
0028217720
-
Chimeric molecules created by gene amplification interfere with the analysis of somatic hypermutation of murine immunoglobulin genes
-
Ford JE, McHeyzer-Williams MG, Lieber MR: Chimeric molecules created by gene amplification interfere with the analysis of somatic hypermutation of murine immunoglobulin genes. Gene 1994, 142:279-283. These studies highlight the need for a single-cell substrate in the analysis of somatic hypermutation (most especially for the analysis of populations of cells expressing somatic variants of the same gene).
-
(1994)
Gene
, vol.142
, pp. 279-283
-
-
Ford, J.E.1
McHeyzer-Williams, M.G.2
Lieber, M.R.3
-
55
-
-
0027491651
-
Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections
-
Kuppers R, Zhao M, Hansmann ML, Rajewsky K: Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections. EMBO J 1993, 12:4955-4967.
-
(1993)
EMBO J
, vol.12
, pp. 4955-4967
-
-
Kuppers, R.1
Zhao, M.2
Hansmann, M.L.3
Rajewsky, K.4
-
56
-
-
0039310043
-
Use of peptide libraries to map the substrate specificity of a peptide-modifying enzyme: A 13 residue consensus peptide specifies biotinylation in Escherichia Coli
-
Schatz P: Use of peptide libraries to map the substrate specificity of a peptide-modifying enzyme: a 13 residue consensus peptide specifies biotinylation in Escherichia Coli. Biotechnology 1993, 11:1138-1143.
-
(1993)
Biotechnology
, vol.11
, pp. 1138-1143
-
-
Schatz, P.1
|