Conditional knockout of the Smad1 gene

Genesis

Volumn 32, Issue 2, 2002, Pages 76-79

  Huang, Shixia ^a   Tang, Binwu ^a   Usoskin, Dmitry ^b   Lechleider, Robert J ^a   Jamin, Soazik P ^c   Li, Cuiling ^d   Anzano, Mario A ^a   Ebendal, Ted ^b   Deng, Chuxia ^d   Roberts, Anita B ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UPPSALA UNIVERSITY   (Sweden)

^c UNIVERSITY OF TEXAS   (United States)

^d NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; CRE RECOMBINASE; GENE PRODUCT; LOX PROTEIN; MUELLERIAN INHIBITING FACTOR; PROTEIN SERINE THREONINE KINASE; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLASTOCYST; CELL VIABILITY; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION; GENE INSERTION; GENE ISOLATION; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; GENE TARGETING; INTRON; KNOCKOUT GENE; KNOCKOUT MOUSE; LETHAL MUTANT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SIGNAL TRANSDUCTION; SMAD1 GENE; SOUTHERN BLOTTING;

ANIMALS; DNA-BINDING PROTEINS; FEMALE; MALE; MICE; MICE, KNOCKOUT; SMAD PROTEINS; SMAD1 PROTEIN; TRANS-ACTIVATORS;

ANIMALIA; INSERTION SEQUENCES;

EID: 0036195946     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/gene.10059     Document Type: Article

References (15)

1. BMPR-IA signaling is required for the formation of the apical ectodermal ridge and dorsal-ventral patterning of the limb
2. Expression of SMAD signal transduction molecules in the pancreas
3. Müllerian inhibiting substance signaling uses a bone morphogenetic protein (BMP)-like pathway mediated by ALK2 and induces SMAD6 expression
4. FGFR-3 is a negative regulator in bone growth
5. Immunohistochemical expression of Smads 1 - 6 in the 15-day gestation mouse embryo: Signaling by BMPs and TGF-betas
6. Characterization of the mouse Smad1 gene and its expression pattern in adult mouse tissues
7. Targeted mutagenesis of Smad1 reveals an essential role in chorioallantoic fusion
8. Use of an internal ribosome entry site for bicistronic expression of Cre recombinase or rtTA transactivator
9. Transforming growth factor beta signaling through Smad1 in human breast cancer cells
10. How cells read TGF-beta signals
11. Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis
12. Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis
13. Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation
14. Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation
15. The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice