Angiogenic and lymphangiogenic molecules in hematological malignancies

Leukemia and Lymphoma

Volumn 43, Issue 2, 2002, Pages 219-224

  Orpana, Arto ^a   Salven, Petri ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Angiogenesis; bFGF; Hematologic malignancies; Leukemia; Lymphangiogenesis; Lymphoma; Lymphoproliferative disorders; Multiple myeloma; VEGF; VEGF C

Indexed keywords

ANGIOGENESIS INHIBITOR; ANGIOGENIC FACTOR; ANTINEOPLASTIC AGENT; BASIC FIBROBLAST GROWTH FACTOR; GROWTH FACTOR; GROWTH FACTOR RECEPTOR; LYMPHANGIOGENIC FACTOR; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN C; VASCULOTROPIN RECEPTOR;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; CANCER CELL; CANCER IMMUNOTHERAPY; CELL PROLIFERATION; CELL SURVIVAL; CLINICAL FEATURE; CONCENTRATION (PARAMETERS); ENDOTHELIUM CELL; GROWTH REGULATION; HEMATOLOGIC DISEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; LEUKEMIA; LYMPHOMA; MALIGNANT NEOPLASTIC DISEASE; MOUSE; MULTIPLE MYELOMA; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; REVIEW;

ANIMALS; ENDOTHELIAL GROWTH FACTORS; FIBROBLAST GROWTH FACTOR 2; GROWTH SUBSTANCES; HEMATOLOGIC NEOPLASMS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOKINES; NEOVASCULARIZATION, PATHOLOGIC; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR C; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0036194342     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.1080/10428190290005964     Document Type: Review

References (79)

1. "Angiogenesis in the female reproductive system"
2. "Angiogenesis in cancer, vascular, rheumatoid and other disease"
3. "Differentiation of endothelium"
4. "Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis"
5. "Vascular-specific growth factors and blood vessel formation"
6. "Angiogenesis: Potential for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, chronic inflammation"
7. "Tumour angiogenic factor associated with subcutaneous lymphoma"
8. "Spectrum of tumor angiogenesis in the bone marrow of children with acute lymphoblastic leukemia"
9. "Evidence of increased angiogenesis in patients with acute myeloid leukemia"
10. "Increased angiogenesis in the bone marrow of patients with acute myeloid leukemia"
11. "Angiogenesis in acute and chronic leukemias and myelodysplastic syndromes"
12. "Angiogenesis in myelodysplastic syndromes"
13. "Angiogenesis spectrum in the stroma of B-cell non-Hodgkin's lymphomas. An immunohistochemical and ultrastructural study"
14. "Angiogenesis extent and macrophage density increase simultaneously with pathological progression in B-cell non-Hodgkin's lymphomas"
15. "Bone marrow angiogenesis and mast cell density increase simultaneously with progression of human multiple myeloma"
16. "Prognostic value of bone marrow angiogenesis in multiple myeloma"
17. "Clinical applications of angiogenic growth factors and their inhibitors"
18. "Endostatin, an antiangiogenic drug, induces tumor stabilization after chemotherapy or anti-CD20 therapy in a NOD/SCID mouse model of human high-grade non-Hodgkin lymphoma"
19. "Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer"
20. "Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis"
21. "The biology of vascular endothelial growth factor"
22. "Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid"
23. "Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene"
24. "Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele"
25. "Expression of vascular endothelial growth factor does not promote transformation but confers a growth advantage in vivo to Chinese hamster ovary cells"
26. "Enhancement of tumor growth and vascular density by transfection of vascular endothelial cell growth factor into MCF-7 human breast carcinoma cells"
27. "Distribution of vascular permeability factor (vascular endothelial growth factor) in tumors: Concentration in tumor blood vessels"
28. "Vascular endothelial growth factors VEGF-B and VEGF-C are expressed in human tumors"
29. "Expression of vascular endothelial growth factor in lymphomas and Castleman's disease"
30. "Vascular endothelial growth factor, a possible paracrine growth factor in human acute myeloid leukemia"
31. "Cellular vascular endothelial growth factor is a predictor of outcome in patients with acute myeloid leukemia"
32. "Human myeloid and lymphoid malignancies in the non-obese diabetic/severe combined immunodeficiency mouse model: Frequency of apoptotic cells in solid tumors and efficiency and speed of engraftment endothelial growth factor production"
33. "Vascular endothelial growth factor and interleukin-6 in paracrine tumor-stromal cell interactions in multiple myeloma"
34. "Atypical lymphoproliferative disorders"
35. "Tumor induction of VEGF promoter activity in stromal cells"
36. "Peripheral blood T lymphocytes and lymphocytes infiltrating human cancers express vascular endothelial growth factor: A potential role for T cells in angiogenesis"
37. "Vascular endothelial growth factor in squamous cell head and neck carcinoma: Expression and prognostic significance"
38. "Leukocytes and platelets of patients with cancer contain high levels of vascular endothelial growth factor"
39. "Endotoxins induce and interferon-α suppresses vascular endothelial growth factor (VEGF) production in human peripheral blood mononuclear cells"
40. "Peripheral blood platelets express VEGF-C and VEGF which are released during platelet activation"
41. "Intracellular pool of vascular endothelial growth factor in human neutrophils"
42. "Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets"
43. "A high pretreatment serum vascular endothelial growth factor concentration is associated with poor outcome in non-Hodgkin's lymphoma"
44. "Simultaneous elevation in the serum concentrations of the angiogenic growth factors VEGF and bFGF is an independent predictor of poor prognosis in non-Hodgkin lymphoma: A single-institution study of 200 patients"
45. "Angiogenic growth factors and endostatin in non-Hodgkin's lymphoma"
46. "Increased serum levels of vascular endothelial growth factor predict risk of progression in early B- cell chronic lymphocytic leukaemia"
47. "Expression of vascular endothelial growth factor and its receptors in hematopoietic malignancies"
48. "Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration"
49. "VEGF acts as a survival factor on leukemia by HSP90-mediated induction of BCL-2 expression"
50. "ZK7, a novel zinc finger gene, is induced by vascular endothelial growth factor and inhibits apoptotic death in hematopoietic cells"
51. "A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases"
52. "Proteolytic processing regulates receptor specificity and activity of VEGF-C"
53. "FLT4 receptor tyrosine kinase contains seven immunoglobulin-like loops and is expressed in multiple human tissues and cell lines"
54. "Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development"
55. "Lymphatic endothelium and Kaposi's sarcoma spindle cells detected by antibodies against the vascular endothelial growth factor receptor-3"
56. "VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer"
57. "Hyperplasia of lymphatic vessels in VEGF-C transgenic mice"
58. "Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3"
59. "Vascular endothelial growth factor C induces angiogenesis in vivo"
60. "Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis"
61. "Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis"
62. "Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice"
63. "Expression of FLT4 and its ligand VEGF-C in acute myeloid lenkemia"
64. "VEGF-C signalling through FLT-4 (VEGFR3) mediates leukemic cell proliferation and survival"
65. "Placenta growth factor and vascular endothelial growth factor B and C expression in microvascular endothelial cells and pericytes. Implication in autocrine and paracrine regulation of angiogenesis"
66. "Molecular mechanisms of angiogenesis: Fibroblast growth factor signal transduction"
67. "Biological roles of fibroblast growth factor-2"
68. "Suppression of solid tumor growth by immunoneutralizing monoclonal antibody against human basic fibroblast growth factor"
69. "Basic fibroblast growth factor expression in human bone marrow and peripheral blood cells"
70. "Constitutive and selective expression of basic fibroblast growth factor in human leukaemia cell lines"
71. "T lymphocytes that infiltrate tumors and atherosclerotic plaques produce heparin-binding epidermal growth factor-like growth factor and basic fibroblast growth factor: A potential pathologic role"
72. "T lymphocytes synthesize and export heparin-binding epidermal growth factor-like growth factor and basic fibroblast growth factor, mitogens by CD4+ and CD8+ T cells"
73. "Human lymphoblastoid cells produce extracellular matrix-degrading enzymes and induce endothelial cell proliferation, migration, morphogenesis angiogenesis"
74. "Expression of basic fibroblast growth factor (bFGF) and FGF-receptors in human leukemic cells"
75. "Basic fibroblast growth factor is expressed by CD19/CD11c-positive cells in hairy cell leukemia"
76. "Elevated intracellular level of basic fibroblast growth factor correlates with stage of chronic lymphocytic leukemia and is associated with resistance to fludarabine"
77. "A high pretreatment serum basic fibroblast growth factor concentration is an independent predictor of poor prognosis in non-Hodgkin's lymphoma"
78. "Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro"
79. "Synergistic effects of vascular endothelial growth factor and basic fibroblast growth factor on the proliferation and cord formation of bovine capillary endothelial cells within collagen gels"