Increased serum levels of vascular endothelial growth factor predict risk of progression in early B-cell chronic lymphocytic leukaemia

British Journal of Haematology

Volumn 107, Issue 3, 1999, Pages 605-610

  Molica, Stefano ^a   Vitelli, Gaetano ^b   Levato, Domenico ^a   Gandolfo, Giuseppe Maria ^b   Liso, Vincenzo ^c  

^a PUGLIESE CIACCIO HOSPITAL   (Italy)

^b REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^c UNIVERSITY OF BARI   (Italy)

Author keywords

Angiogenesis; B CLL; Prognosis; VEGF

Indexed keywords

VASCULOTROPIN;

ADULT; AGED; ANGIOGENESIS; ARTICLE; B CELL LEUKEMIA; CANCER GROWTH; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; RISK FACTOR;

EID: 0032705222     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1999.01752.x     Document Type: Article

References (36)

1. Aguyao, A., Kuntarjian, H., Manshouri, T., Gidel, C., Barlogie, B., Koller, C., O'Brien, S., Albitar, M. & Keating, M. (1998) Low levels of vascular endothelial growth factor (VEGF) in cells of patients with chronic lymphoid leukemia (CLL) correlate with survival, particularly in patients with low beta-2 microglobulin levels. Blood, 92, (Suppl. 1), 226a.
2. Banks, R.E., Forbes, M.A., Kinsey, S.E., Stanley, A., Ingham, E., Walters, C. & Selby, P.J. (1998) Release of the angiogenic cytokine vascular endothelial growth factor (VEGF) from platelets: significance for VEGF measurements and cancer biology. British Journal of Cancer, 77, 956-964.
3. Bellamy, W.T., Richter, L., Frutiger, Y. & Grogan, T.M. (1999) Expression of vascular endothelial growth factor and its receptors in hematopoietic malignancies. Cancer Research, 59, 728-733.
4. Berse, B., Brown, L.F., van de Water, L., Dvokar, H.F. & Senger, D.R. (1992) Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors. Molecular and Cellular Biology, 3, 211-219.
5. Bertolini, F., Paolucci, M., Peccatori, F., Cinieri, S., Agazzi, A., Ferrucci, P.F., Cocorocchio, E., Goldhirsch, A. & Martinelli, G. (1999) Angiogenic growth factors and endostatin in non-Hodgkin's lymphoma. British Journal of Haematology, 106, 504-509.
6. Binet, J.L., Auquier, A., Dighiero, G., Chastang, C., Piguet, H., Goasguen, J., Vaugier, G., Potron, G., Colona, P., Oberling, F., Thomas, M., Tchernia, G., Jacquillat, C., Boivin, P., Lesty, C., Duault, M.T., Monconduit, M., Belabbes, S. & Gremy, F. (1981) A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis. Cancer, 48, 198-212.
7. Cheson, B.D., Bennett, J.M., Grever, M., Kay, N., Keating, M.J., O'Brien, S. & Rai, K.R. (1996) National Institute-sponsored working group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment. Blood, 87, 4990-4997.
8. Cohen, T., Nahari, D., Cerem, L.W., Neufeld, G. & Levi, B.Z. (1996) Interleukin 6 induces the expression of vascular endothelial growth factor. Journal of Biological Chemistry, 271, 736-743.
9. Dighiero, G., Maloum, K., Desablens, B., Cazin, B., Navarro, M., Leblay, R., Leporrier, M., Jaubert, J., Lepeu, G., Dreyfus, B., Binet, J.L. & Travade, P. (1998) Chlorambucil in indolent chronic lymphocytic leukemia. New England Journal of Medicine, 338, 1506-1514.
10. Dirix, L.Y., Vermeulen, P.B., Hubens, G., Benoy, I., Martin, M., De Pooter, C. & Van Oosterom, A.T. (1996) Serum basic fibroblast growth factor and vascular endothelial growth factor and tumour growth kinetics in advanced colorectal cancer. Annals of Oncology, 7, 843-848.
11. Dunst, J., Pigorsch, S., Hansgen, G., Hintner, I., Lautenschlager, C. & Becker, A. (1999) Low hemoglobin is associated with increased levels of vascular endothelial growth factor (VEGF) in cancer patients. Does anemia stimulate angiogenesis? Strahlenther Onkologie, 175, 93-96.
12. Esch, F., Baird, A., Ling, N., Ueno, N., Hill, F. & Deneroy, L. (1985) Primary structure of bovine fibroblastic growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF. Proceedings of the National Academy of Sciences of the United States of America, 82, 6507-6511.
13. Folkman, J. (1995) Angiogenesis in cancer, vascular, rheumatoid and other disease. Nature Medicine, 1, 27-31.
14. Frank, S., Hubner, G., Breier, G., Longaker, M.T., Greenhalgh, D.G. & Werner, S. (1995) Regulation of vascular endothelial growth factor expression in cultured keratinocytes: implications for normal and impaired wound healing. Journal of Biological Chemistry, 270, 1260-1267.
15. Freeman, M.R., Schneck, F.X., Gagnon, M.L., Corless, C., Soker, S., Niknejad, K., Peoples, G.E. & Klagsbrun, M. (1995) Peripheral blood T lymphocytes and lymphocytes infiltrating human cancers express vascular endothelial growth factor: a potential role for T cells in angiogenesis. Cancer Research, 55, 4140-4149.
16. French Cooperative Group on Chronic Lymphocytic Leukaemia (1990) Natural history of stage A chronic lymphocytic leukaemia untreated patients. British Journal of Haematology, 76, 45-62.
17. Gasparini, G. & Harris, A.L. (1995) Clinical importance of the determination of tumor angiogenesis in breast carcinoma: much more than a new prognostic tool. Journal of Clinical Oncolology, 13, 765-782.
18. Hallek, M., Langenmayer, I., Nerl, C., Knauf, W., Dietzfelbinger, H., Adorf, D., Ostwald, M., Busch, R., Kuhn-Hallek, I., Thiel, E. & Emmerich, B. (1999) Elevated serum thymidine kinase levels identify a subgroup at high risk of disease progression in early, nonsmoldering chronic lymphocytic leukemia. Blood, 93, 1732-1737.
19. Kini, A.R., Peterson, L.C. & Kay, N.E. (1998) Evidence for abnormal angiogenesis in the bone marrow of patients with B-cell chronic lymphocytic leukemia. Blood, 92, (Suppl. 1), 717a.
20. Li, V.W., Folkerth, R.D. & Watanabe, H. (1994) Microvessel count and cerebrospinal fluid basic fibroblast growth factor in children with brain tumours. Lancet, 344, 82-86.
21. Molica, S. (1991) Progression and survival studies in early chronic lymphocytic leukemia. Blood, 78, 895-899.
22. Molica, S. (1999) Is it time for a reassessment of prognostic features in B-cell chronic lymphocytic leukemia? Hematology and Cell Therapy, 41, 87-93.
23. Molica, S., Levato, D., Cascavilla, N., Levato, L. & Musto, P. (1999) Clinico-prognostic implications of simultaneous increased serum levels of soluble CD23 and beta-2 microglobulin in B-cell chronic lymphocytic leukaemia. European Journal of Haematology, 62, 117-122.
24. Montserrat, E., Sanchez-Bisono, J., Vinolas, N. & Rozman, C. (1986) Lymphocyte doubling time in chronic lymphocytic leukaemia: analysis of its prognostic significance. British Journal of Haematology, 62, 567-578.
25. Montserrat, E., Vinolas, N., Reverter, J.C. & Rozman, C. (1988) Natural history of chronic lymphocytic leukemia: on the progression and prognosis of early stages. Nouvelle Revue Française d'Hématologie, 30, 359-361.
26. Morrison, V.A. (1998) The infectious complications of chronic lymphocytic leukemia. Seminars in Oncology, 25, 98-106.
27. Nakamura, T., Nawa, K. & Ichiara, A. (1984) Partial purification and characterization of hepatocyte growth factor from serum of hepatomized rats. Biochemical and Biophysical Research Communications, 122, 1450-1459.
28. Perez-Atayade, A.R., Sallan, S.E., Tedrow, U., Connors, E.A. & Folkman, J. (1997) Spectrum of tumor angiogenesis in the bone marrow of children with acute lymphoblastic leukemia. American Journal of Pathology, 150, 815-821.
29. Rai, K.R., Sawitsky, A., Cronkite, E.P., Chanana, A.D., Levy, N.R. & Pasternack, B.S. (1975) Clinical staging of chronic lymphocytic leukemia. Blood, 46, 219-234.
30. Rozman, C., Montserrat, E., Rodriguez-Fernandez, J.M., Ayats, R., Vallespi, T., Parody, R., Rios, A., Prados, D., Morey, M., Gomis, F., Alcala, A., Gutierrez, M., Maldonado, J., Gonzales, G., Giralt, M., Hernandez-Nieto, L., Cabrera, A. & Fernandez-Ranana, J.M. (1984) Bone marrow histologic pattern: the best single prognostic parameter in chronic lymphocytic leukemia: a multivariate survival analysis of 329 cases. Blood, 64, 642-653.
31. Salven, P., Maenpaa, H., Orpana, A., Alitalo, K. & Joensuu, H. (1997) Serum VEGF is often elevated in disseminated cancer. Clinical Cancer Research, 6, 647-651.
32. Sarfati, M., Chevret, S., Chastang, C., Biron, G., Stryckmans, P., Delespesse, G., Binet, J.C., Merle-Beral, H. & Bron, D. (1996) Prognostic importance of serum soluble CD23 level in chronic lymphocytic leukemia. Blood, 88, 4259-4264.
33. Shami, P.J., Hussong, J.W. & Rodgers, G.M. (1998) Evidence of increased angiogenesis in the bone marrow of patients with acute nonlymphocytic leukemia. Blood, 92, (Suppl. 1), 512a.
34. Toi, M., Shinichi, K., Suzuki, H., Yamamoto, Y., Inada, K., Imazawa, T., Taniguchi, T. & Tominaga, T. (1996) Quantitative analysis of vascular endothelial growth factor in primary breast cancer. Cancer, 77, 1101-1106.
35. Vacca, A., Ribatti, D., Presta, M., Minischetti, M., Iurlaro, M., Ria, R., Albini, A., Bussolino, F. & Dammacco, F. (1999) Bone marrow neovascularization, plasma cell angiogenic potential, and matrix metalloproteinase-2 secretion parallel progression of human multiple myeloma. Blood, 93, 3064-3073.
36. Yamamoto, Y., Toi, M., Kondo, S., Matsumoto, T., Suzuki, H., Kitamura, M., Tsurata, K., Taniguchi, T., Okamoto, A., Mori, T., Yoshida, M., Ikeda, T. & Tominaga, T. (1996) Concentrations of vascular endothelial growth factor in the sera of normal controls and cancer patients. Clinical Cancer Research, 2, 821-826.