Essential role of ICAM-1/LFA-1 interaction in synergistic effect of IL-18 and IL-12 on IFN-γ production in human PBMC

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 365, Issue 3, 2002, Pages 181-186

  Yoshida, Atsushi ^a   Takahashi, Hideo Kohka ^a   Iwagaki, Hiromi ^a   Yoshino, Tadashi ^a   Morichika, Toshihiko ^a   Yokoyama, Minori ^a   Itoh, Hideyuki ^a   Mori, Shuji ^a   Akagi, Tadaatsu ^a   Nishibori, Masahiro ^a   Tanaka, Noriaki ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

ICAM 1; IFN ; IL 12; IL 18; LFA 1; Monocytes

Indexed keywords

GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 12; INTERLEUKIN 18; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1;

ANTIGEN EXPRESSION; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; INTERFERON PRODUCTION; MONONUCLEAR CELL; NATURAL KILLER CELL; NORMAL HUMAN; PROTEIN INTERACTION; T LYMPHOCYTE;

ANTIBODIES, MONOCLONAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-18; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MONOCYTES; UP-REGULATION;

EID: 0036193180     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-001-0518-6     Document Type: Article

References (18)

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2. IL-12 and IL-18 differentially regulate the transcriptional activity of the human IFN-gamma promoter in primary CD4+ T lymphocytes
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4. Lineage-specific requirement for signal transducer and activator of transcription (Stat)4 in interferon gamma production from CD4(+) versus CD8(+) T cells
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