Complement activation alters myocellular sodium homeostasis during polymicrobial sepsis

Critical Care Medicine

Volumn 30, Issue 3, 2002, Pages 684-691

  Wang, Weiyang ^a   Okamoto, Ken ^a   Jacobs, Danny O ^a  

^a CREIGHTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Complement activation; Complement membrane attack complex; Critical care; Na+ K+ exchanging adenosine triphosphatase; Potassium; Protein kinase C; Septic shock; Skeletal muscle; Sodium; Zymosan

Indexed keywords

COMPLEMENT MEMBRANE ATTACK COMPLEX; COMPLEMENT RECEPTOR; PROTEIN KINASE C; SOLUBLE COMPLEMENT RECEPTOR 1; UNCLASSIFIED DRUG; ZYMOSAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CECUM; COMPLEMENT ACTIVATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTENSOR DIGITORUM LONGUS MUSCLE; IMMUNOPATHOLOGY; INTENSIVE CARE; MALE; MUSCLE CELL; MUSCLE CONTRACTION; NONHUMAN; POTASSIUM CELL LEVEL; PRIORITY JOURNAL; RAT; SEPSIS; SIGNAL TRANSDUCTION; SODIUM BALANCE; SODIUM CELL LEVEL;

EID: 0036186072     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200203000-00031     Document Type: Article

References (56)

1. The effects of alterations in membrane sodium transport on rat aortic smooth muscle proliferation
2. Ouabain induces inhibition of the progression phase in human T-cell proliferation
3. Sodium overload through voltage-dependent Na(+) channels induces necrosis and apoptosis of rat superior cervical ganglion cells in vitro
4. + efflux in the activation of apoptosis
5. + ratio blocks apoptosis in vascular smooth muscle at a site upstream of caspase-3
6. Terminal complement complexes and anaphylatoxin in septic and ischemic patients
7. Elevated plasma levels of anaphylatoxins C3a and C4a are associated with a fatal outcome in sepsis
8. Complement activation in relation to capillary leakage in children with septic shock and purpura
9. Complement and leukocyte activation in septic baboons
10. Activation of the complement system in baboons challenged with live Escherichia coli: Correlation with mortality and evidence for a biphasic activation pattern
11. Effect of C1 inhibitor on inflammatory and physiologic response patterns in primates suffering from lethal septic shock
12. Anti-TNF treatment of baboons with sepsis reduces TNF-alpha, IL-6 and IL-8, but not the degree of complement activation
13. Cytotoxic action and other metabolic consequences of terminal complement proteins
14. Membrane signaling by complement C5b-9, the membrane attack complex
15. Regulation of the complement membrane attack pathway
16. Endotoxin-induced shock in the rat: A role for C5a
17. Effects of anti-C5a antibodies on the adult respiratory distress syndrome in septic primates
18. Therapeutic inhibition of the complement system: Y2K update
19. Skeletal muscle reperfusion injury is mediated by neutrophils and the complement membrane attack complex
20. Protective effects of soluble CR1 in complement- and neutrophil-mediated injury
21. The complement regulators C1 inhibitor and soluble complement receptor 1 attenuate acute lung injury in rabbits
22. Effect of soluble complement receptor-1 on neutrophil accumulation after traumatic brain injury in rats
23. Soluble recombinant complement receptor 1 inhibits inflammation and demyelination in antibody-mediated demyelinating experimental allergic encephalomyelitis
24. Phase I trial of the recombinant soluble complement receptor 1 in acute lung injury and acute respiratory distress syndrome
25. Assessment of the early cellular membrane response to live Escherichia coli bacteremia
26. Effect of sepsis on intracellular sodium activity, sodium concentration, and water content in thermal injured rat
27. Cell desensitization by sublytic C5b-9 complexes and calcium ionophores depends on activation of protein kinase C
28. Complement activates phospholipases and protein kinases in glomerular epithelial cells
29. Complement resistance of tumor cells: Basal and induced mechanisms
30. Sublytic complement attack increases intracellular sodium in rat skeletal muscle
31. In vitro complement activation favoring soluble C5b-9 complex formation alters myocellular sodium homeostasis
32. + in rat slow- and fast-twitch muscle
33. Linkage of aerobic glycolysis to sodium-potassium transport in rat skeletal muscle
34. Protein kinase C modulates insulin action in human skeletal muscle
35. Experimental approaches in muscle metabolism: Hindlimb perfusion and isolated muscle incubation
36. Soluble complex of complement increases hydraulic conductivity in single microvessels of rat lung
37. Effects of complement activation in the isolated heart: Role of the terminal complement components
38. Sublytic terminal complement attack on myotubes decreases the expression of mRNAs encoding muscle-specific proteins
39. Activation of the alternative complement pathway and production of factor H by skeletal myotubes
40. Human skeletal myoblasts spontaneously activate allogeneic complement but are resistant to killing
41. Complement induces a transient increase in membrane permeability in unlysed erythrocytes
42. Transient changes in erythrocyte membrane permeability are induced by sublytic amounts of the complement membrane attack complex (C5b-9)
43. C5a receptor antagonists
44. Protein kinase C is isoenzymes: Divergence in signal transduction?
45. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C
46. Rottlerin, a novei protein kinase inhibitor
47. Complement activation and atherosclerosis
48. Mechanisms of sodium pump regulation
49. +
50. The complement SC5b-9 complex mediates cell adhesion through a vitronectin receptor
51. Structure and biological role of vitronectin
52. Ligation of endothelial alpha v beta 3 integrin increases capillary hydraulic conductivity, of rat lung
53. Dual signaling by the alpha(v)beta(3)-integrin activates cytosolic PLA(2) in bovine pulmonary artery endothelial cells
54. Soluble ligands of the alpha v beta 3 integrin mediate enhanced tyrosine phosphorylation of multiple proteins in adherent bovine pulmonary artery endothelial cells
55. The role of protein kinase C in lipopolysaccharide-induced myocardial depression in guinea pigs
56. Protein kinase C activity is increased in rat heart during the early hyperdynamic phase of sepsis