Complement activation in relation to capillary leakage in children with septic shock and purpura

Infection and Immunity

Volumn 66, Issue 11, 1998, Pages 5350-5356

  Hazelzet, Jan A ^a   De Groot, Ronald ^a   Van Mierlo, Gerard ^c   Joosten, Koen F M ^a   Van Der Voort, Edwin ^a   Eerenberg, Anke ^c   Suur, Marja H ^a   Hop, Wim C J ^b   Hack, C Erik ^c  

^a SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^b ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; COMPLEMENT; COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C3B; COMPLEMENT COMPONENT C4B; CYTOKINE; ELASTASE; INTERLEUKIN 6; INTERLEUKIN 8; LACTOFERRIN; PHOSPHOLIPASE A2;

ADOLESCENT; ADULT; ARTICLE; BLOOD SAMPLING; BLOOD VESSEL PERMEABILITY; CAPILLARY LEAK SYNDROME; CHILD; COMPLEMENT ACTIVATION; FEMALE; HOSPITAL ADMISSION; HUMAN; INFANT; INFLAMMATORY CELL; MAJOR CLINICAL STUDY; MALE; MEDIATOR RELEASE; PRIORITY JOURNAL; PURPURA; RECURRENT INFECTION; SEPTIC SHOCK; SURVIVAL; TARGET CELL;

EID: 0032411277     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.11.5350-5356.1998     Document Type: Article

References (5)

1. Beatty, D. W., C. R. Ryder, and H. D. Heese. 1986. Complement abnormalities during an epidemic of group B meningococcal infection in children. Clin. Exp. Immunol. 64:465-470.
2. Bone, R. C. 1992. Inhibitors of complement and neutrophils: a critical evaluation of their role in the treatment of sepsis. Crit. Care Med. 20:891-898.
3. Brandtzaeg, P. 1996. Systemic meningococcal disease: clinical pictures and pathophysiological background. Rev. Med. Microbiol. 7:63-72.
4. Brandtzaeg, P., K. Hogasen, P. Kierulf, and T. E. Mollnes. 1996. The excessive complement activation in fulminant meningococcal septicemia is predominantly caused by alternative pathway activation. J. Infect. Dis. 173:647-655.
5. Brandtzaeg, P. B., T. E. Mollnes, and P. Kierulf. 1989. Complement activation and endotoxin levels in systemic meningococcal disease. J. Infect. Dis. 160:58-65.