Skeletal muscle mRNA levels for cathepsin B, but not components of the ubiquitin-proteasome pathway, are increased in patients with lung cancer referred for thoracotomy

Clinical Science

Volumn 102, Issue 3, 2002, Pages 353-361

  Jagoe, R Thomas ^a   Redfern, Christopher P F ^a   Roberts, Russell G ^a   Gibson, G John ^a   Goodship, Timothy H J ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Cathepsin B; Fat free mass; Lung cancer; Muscle wasting; Nutritional status; Ubiquitin

Indexed keywords

CATHEPSIN B; PROTEASOME; UBIQUITIN;

ARTICLE; CACHEXIA; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; LUNG CANCER; LYSOSOME; MUSCLE ATROPHY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DEGRADATION; SKELETAL MUSCLE; THORACOTOMY;

AGED; ANALYSIS OF VARIANCE; BLOTTING, NORTHERN; CACHEXIA; CASE-CONTROL STUDIES; CATHEPSIN B; CATHEPSIN D; CYSTEINE ENDOPEPTIDASES; FEMALE; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HUMANS; LIGASES; LUNG NEOPLASMS; MALE; MIDDLE AGED; MULTIENZYME COMPLEXES; MUSCLE, SKELETAL; NEOPLASM STAGING; NUTRITIONAL STATUS; POLYUBIQUITIN; PROTEASOME ENDOPEPTIDASE COMPLEX; RNA, MESSENGER; SMOKING; UBIQUITIN-CONJUGATING ENZYMES;

EID: 0036185466     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20010270     Document Type: Article

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