Proteolytic action of duodenase is required to induce DNA synthesis in pulmonary artery fibroblasts: A role for phosphoinositide 3-kinase

European Journal of Biochemistry

Volumn 269, Issue 4, 2002, Pages 1171-1180

  Pemberton, Alan D ^a   Zamolodchikova, Tatyana S ^b   Scudamore, Cheryl L ^a   Chilvers, Edwin R ^c   Miller, Hugh R P ^a   Walker, Trevor R ^d  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Duodenase; Fibroblasts; Phosphoinositide 3 kinase; Protease activated receptor

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 2 MORPHOLINO 8 PHENYLCHROMONE; BRADYKININ; CHYMOTRYPSIN; DUODENASE; G PROTEIN COUPLED RECEPTOR; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); INTERLEUKIN 1BETA; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEINASE; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; PROTEINASE ACTIVATED RECEPTOR 4; SOYBEAN TRYPSIN INHIBITOR; THROMBIN; THYMIDINE; TRYPSIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; WORTMANNIN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; CALCIUM MOBILIZATION; CELL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SYNTHESIS; DRUG EFFECT; ENZYME ACTIVITY; ENZYME LOCALIZATION; FIBROBLAST; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PULMONARY ARTERY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID SEQUENCE; ANIMALS; CATTLE; DNA; FIBROBLASTS; INTERLEUKIN-1; INTESTINES; MOLECULAR SEQUENCE DATA; PULMONARY ARTERY; RECEPTOR, PAR-1; RECEPTOR, PAR-2; RECEPTORS, THROMBIN; SERINE ENDOPEPTIDASES; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; GLYCINE MAX;

EID: 0036183147     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1033.2002.02747.x     Document Type: Article

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