Increased cisplatin sensitivity of human fibroblasts from a subject with inherent glutathione deficiency

Acta Oncologica

Volumn 35, Issue 6, 1996, Pages 683-690

  Hansson, Johan ^a   Edgren, Margareta R ^b   Egyházi, Suzanne ^a   Hao, Xiao Yong ^c   Mannervik, Bengt ^c   Ringborg, Ulrik ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELLS; DNA; DRUG THERAPY; ENZYME KINETICS; ENZYMES; HEALTH RISKS; LIVING SYSTEMS STUDIES; RADIATION EFFECTS; RADIOTHERAPY; ULTRAVIOLET RADIATION;

CISPLATIN; FIBROBLASTS; GLUTATHIONE DEFICIENCY; GLUTATHIONE TRANSFERASE;

ONCOLOGY;

CARBOPLATIN; CISPLATIN; MELPHALAN;

ARTICLE; CONTROLLED STUDY; DRUG SENSITIVITY; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

EID: 0029912625     PISSN: 0284186X     EISSN: None     Source Type: Journal    
DOI: 10.3109/02841869609083999     Document Type: Article

References (33)

1. Loehrer PJ, Einhorn LH. Cisplatin. Ann Intern Med 1984; 100: 704-13.
2. Kastan MB, Onyekwere O, Sidransky D, Vogelstein B, Craig RW. Participation of p53 protein in the cellular response to DNA damage. Cancer Res 1991; 51: 6304-11.
3. Fritsche M, Haessler C, Brander G. Induction of nuclear accumulation of the tumor-supressor protein p53 by DNA-damaging agents. Oncogene 1993; 8: 307-18.
4. Behrens BC, Hamilton TC, Masuda H, et al. Characterization of a cis-diamminedichloroplatinum(II)-resistant human ovarian cancer cell line and its use in evaluation of platinum analogues. Cancer Res 1987; 47: 414-8.
5. Richon VM, Schulte N, Eastman A. Multiple mechanisms of resistance to cis-diamminedichloroplatinum(II) in murine leukemia L1210 cells. Cancer Res 1987; 47: 2056-61.
6. Bedford P, Walker MC, Sharma HL, et al. Factors influencing the sensitivity of two human bladder carcinoma cell lines to cis-diamminedichloroplatinum(II). Chem Biol Interact 1987; 61: 1-15.
7. Hospers GAP, Mulder NH, de Jong B, et al. Characterization of a human small cell lung carcinoma cell line with acquired resistance to cis-diamminedichloroplatinum(II) in vitro. Cancer Res 1988; 48: 6803-7.
8. Sekiya S, Oosaki T, Andoh S, Suzuki N, Akaboshi M, Takamizawa H. Mechanisms of resistance to cis-diamminedichloroplatinum(II) in a rat ovarian carcinoma cell line. Eur J Cancer Clin Oncol 1989; 25: 429-37.
9. Hansson J, Fichtinger-Schepman AMJ, Edgren M, Ringborg U. Comparative study of two human melanoma cell lines with different sensitivities to mustine and cisplatin. Eur J Cancer 1991; 27: 1039-45.
10. Hansson J, Edgren M, Ehrsson H, Ringborg U, Nilsson B. Effect of D,L-buthionine-S,R-sulfoximine on cytotoxicity and DNA cross-linking induced by bifunctional DNA-reactive cytostatic drugs in human melanoma cells. Cancer Res 1988; 48: 19-26.
11. Lai G-M, Ozols RF, Young RC, Hamilton TC. Effect of glutathione on DNA repair in cisplatin-resistant human ovarian cancer cell lines. J Natl Cancer Inst 1989; 81: 535-9.
12. Andrews PA, Scheifer MA, Murphy MP, Howell SB. Enhanced potentiation of cisplatin cytotoxicity in human ovarian carcinoma cells by prolonged glutathione depletion. Chem Biol Interact 1988; 65: 51-8.
13. Tew KD. Glutathione-associated enzymes in anticancer drug resistance. Cancer Res 1994; 54: 4313-20
14. Larsson A. 5-Oxoprolinuria and other inborn errors related to the γ-glutamyl cycle. In: Belton NR, Toothill C, ed. Transport and inherited diseases. Lancaster, UK: MTP Press, 1981: 277-306.
15. Larsson A, Mattsson B, Hagenfeldt L, Moldéus P. Glutathione synthethase deficient human fibroblasts in culture. Clin Chim Acta 1983; 135: 57-64.
16. Tanaka K, Wood RD. Xeroderma pigmentosum and nucleotide excision repair of DNA. Trends Biochem Sci 1994; 19: 83-6.
17. Nüsse M, Kramer J. Flow cytometric analysis of micronuclei found in cells after irradiation. Cytometry 1984; 5: 20-5.
18. Tietze F. Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal Biochem 1969; 27: 502-22.
19. Hao X-Y, Castro VM, Bergh J, Sundström B, Mannervik B. Isoenzyme-specific quantitative immunoassays for cytosolic glutathione transferases and measurement of the enzymes in blood plasma from cancer patients and in tumor cell lines. Biochem Biophys Acta 1994; 1225: 223-30.
20. Rydberg B. The rate of strand separation in alkali of DNA of irradiated mammalian cells. Radiat Res 1975; 61: 274-87.
21. Edgren M, Révész L. Compartmentalised depletion of glutathione in cells treated with buthionine sulfoximine. Br J Radiol 1987; 60: 723-4.
22. Seidegård J, Vorachek WR, Pero RW, Pearson WR. Hereditary differences in the human glutathione S-transferase activity on trans-stilbene oxide are due to a gene deletion. Proc Natl Acad Sci USA 1988; 85: 7293-7.
23. Hansson J, Lewensohn R, Ringborg U. Cis-diamminedichloroplatinum(II) toxicity in human melanoma cells and lymphocytes as related to cellular platinum accumulation, DNA cross-linking and inhibition of DNA synthesis. Acta Oncol 1988; 27: 383-92.
24. Ishikawa T, Ali-Osman F. Glutathione-associated cis-diamminedichloroplatinum(II) metabolism and ATP-dependent efflux from leukemia cells. Molecular characterization of glutathione platinum complex and its biological significance. J Biol Chem 1993; 268: 20116-25.
25. Ishikawa T, Wright CD, Ishizuka H. GS-X pump is functionally overexpressed in cis-diamminedichloroplatinum (II)-resistant human leukemia HL-60 cells and down-regulated by cell differentiation. J Biol Chem 1994; 269: 29085-93.
26. Eastman A. Cross-linking of glutathione to DNA by cancer chemotherapeutic platinum coordination complexes. Chem Biol Interact 1987; 61: 241-8.
27. Sherman SE, Lippard SJ. Structural aspects of platinum anticancer drug interactions with DNA. Chem Rev 1987; 87: 1153-81.
28. Edgren M. Intercellular co-operation in repairing radiation induced single-strand DNA breaks. Int J Radiat Biol 1982; 41: 589-93.
29. Deschavanne PJ, Chavadura N, Debieu D, Malaise EP. Reduced PLD repair ability in glutathione synthetase deficient human fibroblasts after UV irradiation. Int J Radiat Biol 1984; 46: 375-82.
30. Rubin E, Kharbanda S, Gunji H, Weichselbaum R, Kufe D. cis-diamminedichloroplatinum(II) induces C-jun expression in human myeloid leukemia cells: potential involvement of a protein kinase C-dependent signaling pathway. Cancer Res 1992; 52: 878-82.
31. Zhao R, Bendix Rabo Y, Egyházi S, et al. Apoptosis and c-jun. induction by cisplatin in a human melanoma cell line and a drug-resistant daughter cell line. Anticancer Drugs 1995; 6: 657-68.
32. Bergelson S, Pinkus R, Daniel V. Intracellular glutathione levels regulate Fos/Jun induction and activation of glutathione S-transferase gene expression. Cancer Res 1994; 54: 36-40.
33. Bendix Rabo Y, Shoshan MC, Linder S, Hansson J. Different mechanisms are responsible for c-jun mRNA induction by cisplatin and ultraviolet light. Int J Cancer 1996; 65: 821-6.