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Volumn 37, Issue 1, 2002, Pages 83-89
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2-Arylalkyl-substituted anthracenones as inhibitors of 12-lipoxygenase enzymes. 2. Structure-activity relationships of the linker chain
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Author keywords
12(S) HETE; 12 lipoxygenase; 5 lipoxygenase; Anthracenone; Lipophilicity
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Indexed keywords
1,8 DIHYDROXY 2 [2 (3 HYDROXY 4 METHOXYPHENYL)ETHYL] 9(10H)ANTHRACENONE;
1,8 DIHYDROXY 2 [2 (3,4 DIHYDROXYPHENYL)ETHYL] 9(10H)ANTHRACENONE;
1,8 DIHYDROXY 2 [2 (3,4 DIMETHOXYPHENYL)ETHYL] 9(10H)ANTHRACENONE;
1,8 DIHYDROXY 2 [2 (4 HYDROXYPHENYL)ETHYL] 9(10H)ANTHRACENONE;
1,8 DIHYDROXY 2 [2 (4 METHYLPHENYL)ETHYL] 9(10H)ANTHRACENONE;
2 [2 (4 CHLOROPHENYL)ETHYL] 1,8 DIHYDROXY 9 (10H)ANTHRACENONE;
4 [2 (9,10 DIHYDRO 1,8 DIHYDRO 9 OXO 2 ANTHRACENYL)ETHYL]BENZONITRILE;
ANTHRACENONE;
ANTHRAQUINONE;
ARACHIDONATE 12 LIPOXYGENASE;
ENZYME INHIBITOR;
ISOENZYME;
UNCLASSIFIED DRUG;
ANIMAL CELL;
ANIMAL TISSUE;
ARTICLE;
CATTLE;
CHEMICAL REACTION;
CHEMICAL STRUCTURE;
CONTROLLED STUDY;
DRUG ACTIVITY;
DRUG MECHANISM;
DRUG POTENCY;
DRUG SELECTIVITY;
DRUG SYNTHESIS;
ENZYME INHIBITION;
EPIDERMIS;
HOMOGENATE;
HORNER WADSWORTH EMMONS REACTION;
LEUKOCYTE;
LIPOPHILICITY;
MARSCHALK REACTION;
MOUSE;
NONHUMAN;
REDUCTION;
STRUCTURE ACTIVITY RELATION;
STRUCTURE ANALYSIS;
SWINE;
THROMBOCYTE;
WITTIG REACTION;
ANIMALS;
ANTHRACENES;
ARACHIDONATE 12-LIPOXYGENASE;
BLOOD PLATELETS;
CATTLE;
LEUKOCYTES;
MICE;
SKIN;
STRUCTURE-ACTIVITY RELATIONSHIP;
SWINE;
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EID: 0036180525
PISSN: 02235234
EISSN: None
Source Type: Journal
DOI: 10.1016/S0223-5234(01)01291-0 Document Type: Article |
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Times cited : (6)
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References (35)
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