Isoxazolo[3,4-d]pyridazinones and analogues as Leishmania mexicana PDE inhibitors

Farmaco

Volumn 57, Issue 2, 2002, Pages 89-96

  Dal Piaz, Vittorio ^a   Rascon A ^b   Dubra, M E ^b   Giovannoni, M P ^a   Vergelli, C ^a   Castellana, M C ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b FACULTAD DE CIENCIAS   (Venezuela)

Author keywords

Isoxazolopyridazinones; Leishmania mexicana; Phosphodiesterase inhibitors

Indexed keywords

PHOSPHODIESTERASE INHIBITOR; PYRIDAZINONE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; LEISHMANIA MEXICANA; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; HYDROLYSIS; LEISHMANIA MEXICANA; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; PYRIDAZINES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 0036177833     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(01)01188-0     Document Type: Article

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