Synthesis and evaluation as platelet aggregation inhibitors of 6-phenyl-2,4-substituted-3(2H)-pyridazinones and their rigid analogues benzo[h]cinnolin-3,5-diones

Drug Design and Discovery

Volumn 14, Issue 1, 1996, Pages 53-75

  Dal Piaz, Vittorio ^a   Ciciani, Giovanna ^a   Giovannoni, Maria Paola ^a   Franconi, Flavia ^b  

^a Dipto di Scienze Farmaceutiche   (Italy)

^b UNIVERSITY OF SASSARI   (Italy)

Author keywords

3(2H) pyridazinones benzo h cinnolinones synthesis antiplatelet activity

Indexed keywords

ADENYLATE CYCLASE; ANTITHROMBOCYTIC AGENT; CYCLIC AMP; NITRIC OXIDE; PHOSPHODIESTERASE; PROSTAGLANDIN; PYRIDAZINONE DERIVATIVE; THROMBOXANE;

ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; THROMBOCYTE; THROMBOCYTE AGGREGATION INHIBITION;

BLOOD PLATELETS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PLATELET AGGREGATION INHIBITORS; PYRIDAZINES;

EID: 0029936772     PISSN: 10559612     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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