Adenoviral vectors stimulate murine natural killer cell responses and demonstrate antitumor activities in the absence of transgene expression

Molecular Therapy

Volumn 5, Issue 2, 2002, Pages 115-124

  Ruzek, Melanie C ^a   Kavanagh, Brian F ^a   Scaria, Abraham ^b   Richards, Susan M ^a   Garman, Richard D ^a  

^a Cell and Protein Therapeutics RandD   (United States)

^b GENZYME CORPORATION   (United States)

Author keywords

Adenoviral vectors; Gene therapy; Immunotherapy; Interferon (IFN ); Melanoma; NK cells

Indexed keywords

ADENOVIRUS VECTOR; ALPHA INTERFERON; CD71 ANTIGEN; GENE PRODUCT; GLYCOPROTEIN GP 100; INTERLEUKIN 12; POLYINOSINIC POLYCYTIDYLIC ACID; PROLACTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER IMMUNOTHERAPY; CANCER INHIBITION; CELL ACTIVATION; CELLULAR IMMUNITY; CONTROLLED STUDY; FEMALE; GENETIC CODE; GENETIC TRANSCRIPTION; HEAT TREATMENT; IMMUNOSTIMULATION; IN VIVO STUDY; LYMPHOCYTE ACTIVATION; MALE; MELANOMA; MOUSE; NATURAL KILLER CELL; NONHUMAN; SPLEEN; TRANSGENE; TUMOR IMMUNITY; ULTRAVIOLET RADIATION; VIRAL GENE DELIVERY SYSTEM; VIRUS INACTIVATION; VIRUS INFECTION; VIRUS REPLICATION;

ADENOVIRIDAE; ANIMALIA; MURINAE;

EID: 0036172113     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2002.0529     Document Type: Article

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