Potent antitumor effects mediated by local expression of the mature form of the interferon-γ inducing factor, interleukin-18 (IL-18)

Gene Therapy

Volumn 6, Issue 5, 1999, Pages 808-815

  Osaki, T ^a   Hashimoto, W ^a   Gambotto, A ^a   Okamura, H ^a   Robbins, P D ^a   Kurimoto, M ^a   Lotze, M T ^a   Tahara, H ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Gene therapy; IL 12; Leader sequence; Virus vector

Indexed keywords

CD8 ANTIGEN; COMPLEMENTARY DNA; INTERLEUKIN 12; INTERLEUKIN 18; VIRUS VECTOR;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; FIBROSARCOMA; GENE CONSTRUCT; GENE EXPRESSION; GENE THERAPY; GENETIC TRANSFECTION; INTRADERMAL DRUG ADMINISTRATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; RETROVIRUS; TUMOR CELL; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALS; FIBROSARCOMA; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; INTERFERON TYPE II; INTERLEUKIN-18; MICE; MICE, INBRED C57BL; NEOPLASMS, EXPERIMENTAL; PARATHYROID HORMONE; RANDOM ALLOCATION; RECOMBINANT FUSION PROTEINS; RETROVIRIDAE; TRANSFECTION;

ADENOVIRIDAE; ANIMALIA; MURINAE; UNIDENTIFIED RETROVIRUS;

EID: 0033019078     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300908     Document Type: Article

References (27)