Role of an intact splenic microarchitecture in early lymphocytic choriomeningitis virus production

Journal of Virology

Volumn 76, Issue 5, 2002, Pages 2375-2383

  Müller, Stefan ^a   Hunziker, Lukas ^a   Enzler, Susanne ^a   Bühler Jungo, Myriam ^a   Di Santo, James P ^a   Zinkernagel, Rolf M ^a   Mueller, C ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; HEMOGLOBIN GAMMA CHAIN; IMMUNOGLOBULIN M; LYMPHOTOXIN; RAG2 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACUTE DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOARCHITECTURE; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; DISEASE COURSE; IMMUNE DEFICIENCY; IMMUNE RESPONSE; IMMUNOGLOBULIN DEFICIENCY; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MOUSE; MOUSE STRAIN; NATURAL KILLER CELL; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; SPLEEN; STRAIN DIFFERENCE; T LYMPHOCYTE ACTIVATION; VIRUS INFECTION; VIRUS REPLICATION; VIRUS TITRATION; WILD TYPE;

ADOPTIVE TRANSFER; ANIMALS; ANTIBODIES, VIRAL; B-LYMPHOCYTES; DNA-BINDING PROTEINS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, INBRED C57BL; PLAQUE ASSAY; SPLEEN;

EID: 0036167984     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.76.5.2375-2383.2002     Document Type: Article

References (42)

1. Immunosuppression by lymphocytic choriomeningitis virus infection: Competent effector T and B cells but impaired antigen presentation
2. Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates
3. Lymphotoxin-beta-deficient mice show defective antiviral immunity
4. Lysis of uninfected and virus-infected cells in vivo: A rejection mechanism in addition to that mediated by natural killer cells
5. Virus-induced immunosuppression: Immune system-mediated destruction of virus-infected dendritic cells results in generalized immune suppression
6. Massive expansion of antigen-specific CD8+ T cells during an acute virus infection
7. Identification of alpha-dystroglycan as a receptor for lymphocytic choriomeningitis virus and Lassa fever virus
8. Immunological tolerance to lymphocytic choriomeningitis virus in neonatally infected virus carrier mice: Evidence supporting a clonal inactivation mechanism
9. Redundant role of the Syk protein tyrosine kinase in mouse NK cell differentiation
10. Influence of lymphocytes on the presence and organization of dendritic cell subsets in the spleen
11. Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin
12. Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain
13. Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-alpha double-deficient mice
14. Molecular analysis of viral RNAs in mice persistently infected with lymphocytic choriomeningitis virus
15. B lymphocytes induce the formation of follicular dendritic cell clusters in a lymphotoxin alpha.dependent fashion
16. Enumeration of single IFN-gamma-producing cells in mice during viral and bacterial infection
17. The sequential role of lymphotoxin and B cells in the development of splenic follicles
18. Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
19. On the key role of secondary lymphoid organs in antiviral immune responses studied in alymphoplastic (aly/aly) and spleenless (Hox11(-)/-) mutant mice
20. A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene
21. PrP expression in B lymphocytes is not required for prion neuroinvasion
22. Cells in the marginal zone of the spleen
23. Lymphocytic choriomeningitis virus
24. IgD can largely substitute for loss of IgM function in B cells
25. The immunodepressive action of lymphocytic choriomeningitis virus in mice
26. A high proportion of T lymphocytes that infiltrate H-2-incompatible heart allografts in vivo express genes encoding cytotoxic cell-specific serine proteases, but do not express the MEL-14 defined lymph node homing receptor
27. Counting antigen-specific CD8 T cells: A reevaluation of bystander activation during viral infection
28. Control of early viral and bacterial distribution and disease by natural antibodies
29. Protective T cell-independent antiviral antibody responses are dependent on complement
30. Virus-triggered acquired immunodeficiency by cytotoxic T-cell-dependent destruction of antigen-presenting cells and lymph follicle structure
31. Restricted expression of viral glycoprotein in cells of persistently infected mice
32. Peyer's patch organogenesis is intact yet formation of B lymphocyte follicles is defective in peripheral lymphoid organs of mice deficient for tumor necrosis factor and its 55-kDa receptor
33. Specific cytotoxic T cells eliminate cells producing neutralizing antibodies
34. Crucial role of marginal zone macrophages and marginal zone metallophils in the clearance of lymphocytic choriomeningitis virus infection
35. Septic sequelae after splenectomy for trauma in adults
36. Immunosuppression and resultant viral persistence by specific viral targeting of dendritic cells
37. RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement
38. Differences in affinity of binding of lymphocytic choriomeningitis virus strains to the cellular receptor alphadystroglycan correlate with viral tropism and disease kinetics
39. Virus-lymphocyte interactions. II. Expression of viral sequences during the course of persistent lymphocytic choriomeningitis virus infection and their localization to the L3T4 lymphocyte subset
40. Effect of splenectomy on slowing human immunodeficiency virus disease progression
41. Antigen localisation regulates immune responses in a dose- and time-dependent fashion: A geographical view of immune reactivity
42. General and specific immunosuppression caused by antiviral T-cell responses