Antioxidant vitamin supplements do not reduce reactive oxygen species activity in Helicobacter pylori gastritis in the short term

British Journal of Nutrition

Volumn 87, Issue 1, 2002, Pages 3-11

  Everett, Simon M ^a   Drake, Ian M ^b   White, Kay L M ^a   Mapstone, Nic P ^a   Chalmers, Douglas M ^a   Schorah, Chris J ^a   Axon, Anthony T R ^a  

^a LEEDS GENERAL INFIRMARY   (United Kingdom)

^b Chorley and South Ribble District General Hospital ^*  (United Kingdom)

Author keywords

Ascorbic acid; Gastric carcinoma; Helicobacter pylori; Malondialdehyde; Reactive oxygen species; Vitamin C; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; BISMUTH CITRATE; LIPID; MALONALDEHYDE; METRONIDAZOLE; PLACEBO; REACTIVE OXYGEN METABOLITE; TETRACYCLINE;

ADULT; AGED; ANTIOXIDANT ACTIVITY; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOSE TIME EFFECT RELATION; DOUBLE BLIND PROCEDURE; DRUG EFFECT; ERADICATION THERAPY; FEMALE; GASTRITIS; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; LIPID PEROXIDATION; MAJOR CLINICAL STUDY; MALE; NONHUMAN; RANDOMIZED CONTROLLED TRIAL; SHORT COURSE THERAPY; STOMACH CARCINOGENESIS; STOMACH MUCOSA; VITAMIN BLOOD LEVEL; VITAMIN SUPPLEMENTATION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIOXIDANTS; ASCORBIC ACID; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; FOLLOW-UP STUDIES; GASTRITIS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MALONDIALDEHYDE; MIDDLE AGED; REACTIVE OXYGEN SPECIES; VITAMIN E; VITAMINS;

HELICOBACTER; HELICOBACTER PYLORI; NEGIBACTERIA;

EID: 0036162582     PISSN: 00071145     EISSN: None     Source Type: Journal    
DOI: 10.1079/BJN2001477     Document Type: Article

References (37)

1. Effect of Helicobacter pylori and its eradication on gastric juice ascorbic acid
2. Vitamin C and cancer prevention: The epidemiologic evidence
3. 2 induced DNA damage in human lymphocytes
4. Phospholipid hydroperoxides and lipid peroxidation in liver and plasma ODS rats supplemented with alpha-tocopherol and ascorbic acid
5. The role of antioxidants in gastric carcinogenesis
6. Helicobacter pylori stimulates antral mucosal reactive oxygen metabolite production in vivo
7. Correa P and the participants of the International Workshop on the Histopathology of Gastritis Classification and grading of gastritis. The updated Sydney system
8. Ascorbic acid may protect against human gastric cancer by scavenging mucosal oxygen radicals
9. Reactive oxygen species activity and lipid peroxidation in Helicobacter pylori associated gastritis: Relation to gastric mucosal ascorbic acid concentrations and effect of H. pylori eradication
10. Effect of vitamin C supplementation on gastric mucosal DNA damage
11. Indices of lipid peroxidation in vivo: Strengths and limitations
12. Levels of malondialdehyde-deoxyguanosine in the gastric mucosa - Relationship with lipid peroxidation, ascorbic acid and Helicobacter pylori
13. Gastric antioxidant, nitrites, and mucosal lipoperoxidation in chronic gastritis and Helicobacter pylori infection
14. Ascorbic acid protects lipids in human plasma and low density lipoprotein against oxidative damage
15. Nutritional factors and Helicobacter pylori infection in Colombian children
16. Oxidative mechanisms in carcinogenesis
17. The antioxidant supplement myth
18. Damage to the bases in DNA induced by stimulated human neutrophils
19. Effects of high vitamin C doses on Helicobacter pylori infection and total vitamin C concentration in gastric juice
20. Vitamin E and cancer prevention
21. Selected micronutrient intake and the risk of gastric cancer
22. Vitamin C-induced decomposition of lipid hydroperoxides to endogenous genotoxins
23. Vitamin C pharmacokinetics in healthy volunteers: Evidence for a recommended dietary allowance
24. DNA adducts of α β-unsaturated aldehydes and dicarbonyl compounds
25. Ascorbate-Nitrite reaction: Possible means of blocking the formation of carcinogenic N-nitroso compounds
26. Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinal Efficacy Trial
27. Estimates of worldwide incidence of eighteen major cancers in 1985
28. Plasma free radical activity and antioxidant vitamin levels in dyspeptic patients: Correlation with smoking and Helicobacter pylori infection
29. Chemiluminescence assay of mucosal reactive oxygen metabolites in inflammatory bowel disease
30. Ascorbic acid in the human stomach
31. Levels of nitrite, nitrate, N-nitroso compounds, ascorbic acid and total bile acids in gastric juice of patients with and without precancerous conditions of the stomach
32. Supplementation with α-tocopherol or a combination of α-tocopherol and ascorbic acid protects the gastroeintestinal tract of iron-deficient rats against iron-induced oxidative damage during iron repletion
33. The effects of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers
34. Ascorbic acid and total vitamin C concentrations in plasma, gastric juice, and gastrointestinal mucosa: Effects of gastritis and oral supplementation
35. A simple fluorimetric assay for lipoperoxide in blood plasma