Inherited thrombophilias in pregnant patients: Detection and treatment paradigm

Obstetrics and Gynecology

Volumn 99, Issue 2, 2002, Pages 333-341

  Lockwood, Charles J ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ANTICOAGULANT AGENT; ANTITHROMBIN; BLOOD CLOTTING FACTOR 5 LEIDEN; HEPARIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN C; PROTEIN S; PROTHROMBIN;

ANTICOAGULANT THERAPY; ANTICOAGULATION; ANTITHROMBIN DEFICIENCY; AUTOSOMAL DOMINANT DISORDER; FETUS WASTAGE; FIBRINOLYSIS; GENE MUTATION; HEMOSTASIS; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HYPERHOMOCYSTEINEMIA; INHERITANCE; INTRAUTERINE GROWTH RETARDATION; MATERNAL DISEASE; PATHOPHYSIOLOGY; PREECLAMPSIA; PREGNANCY COMPLICATION; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN C DEFICIENCY; PROTEIN S DEFICIENCY; REVIEW; SOLUTIO PLACENTAE; THROMBOEMBOLISM; THROMBOPHILIA; VEIN THROMBOSIS;

EID: 0036157110     PISSN: 00297844     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0029-7844(01)01760-4     Document Type: Article

References (27)

1. Inherited thrombophilias in pregnant patients
2. Oxygen and placental villous development: Origins of fetal hypoxia
3. The immunobiology and obstetrical consequences of antiphospholipid antibodies
4. Inherited thrombophilia and pregnancy
5. Case-control study of the frequency of thrombophilic disorders in couples with late foetal loss and no thrombotic antecedent
6. Increased frequency of genetic thrombophilia in women with complications of pregnancy
7. Increased fetal loss in women with heritable thrombophilia
8. Factor V Leiden mutation as a risk factor for recurrent pregnancy loss
9. Factor V Leiden and prothrombin G20210A mutations, but not methylenetetrahydrofolate reductase C677T, are associated with recurrent miscarriages
10. There is no association between maternal thrombophilia and recurrent first-trimester loss
11. Hypercoagulable state mutation analysis in white patients with early first-trimester recurrent pregnancy loss
12. Prospective evaluation of the risk conferred by factor V Leiden and thermolabile methylenetetrahydrofolate reductase polymorphisms in pregnancy
13. Ethnic distribution of factor V Leiden in 4047 men and women. Implications for venous thromboembolism screening
14. Association of idiopathic venous thromboembolism with single point-mutation at Arg 506 of factor V
15. Prothrombin and factor V mutations in women with a history of thrombosis during pregnancy and the puerperium
16. Activated protein C resistance can be associated with recurrent fetal loss
17. Severe preeclampsia and high frequency of genetic thrombophilic mutations
18. Thrombophilia-associated pregnancy wastage
19. Mutations in coagulation factors in women with unexplained late fetal loss
20. Plasminogen-activator inhibitor type-1 and coronary artery disease
21. The 4G/4G polymorphism of the hypofibrinolytic plasminogen activator inhibitor type 1 gene: An independent risk factor for serious pregnancy complications
22. Antithrombin mutation database: 2nd (1997) update
23. Hyperhomocysteinaemia and protein S deficiency in complicated pregnancies
24. Hyperhomocysteinemia and recurrent early pregnancy loss: A meta-analysis
25. Safety of withholding heparin in pregnant women with a history of venous thromboembolism. Recurrence of clot in this pregnancy study group
26. Low molecular weight heparin for the prevention of obstetric complications in women with thrombophilia
27. Low molecular weight heparin combined with aspirin in pregnant women with thrombophilia and a history of preeclampsia or fetal growth restriction: A preliminary study