Protons enhance the gating kinetics of the α3/β4 neuronal nicotinic acetylcholine receptor by increasing its apparent affinity to agonists

Molecular Pharmacology

Volumn 61, Issue 2, 2002, Pages 369-378

  Abdrakhmanova, Galya ^a   Dorfman, Julia ^a   Xiao, Yingxian ^a   Morad, Martin ^a  

^a GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; BRAIN RECEPTOR; CARBACHOL; CHOLINERGIC RECEPTOR STIMULATING AGENT; CYTISINE; HYDROGEN; NICOTINE; NICOTINIC RECEPTOR; PROTON;

ACIDIFICATION; ARTICLE; BINDING AFFINITY; CHANNEL GATING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; MEMBRANE CURRENT; NERVE CELL; PH; PKA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON TRANSPORT; SECRETORY VESICLE; SIGNAL TRANSDUCTION;

ALKALOIDS; AZOCINES; CELLS, CULTURED; ELECTROPHYSIOLOGY; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; NEURONS; NICOTINE; NICOTINIC AGONISTS; PROTONS; QUINOLIZINES; RECEPTORS, NICOTINIC; TRANSFECTION;

EID: 0036156232     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.61.2.369     Document Type: Article

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