Assessing the emetic potential of PDE4 inhibitors in rats

British Journal of Pharmacology

Volumn 135, Issue 1, 2002, Pages 113-118

  Robichaud, A ^a   Savoie, C ^a   Stamatiou, P B ^a   Lachance, N ^a   Jolicoeur, P ^a   Rasori, R ^a   Chan, C C ^a  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

Anaesthesia; Emesis; PDE inhibitors

Indexed keywords

1,3,4,5',6,6',7,12B OCTAHYDRO 1',3' DIMETHYL 2H SPIRO[BENZO[B]FURO[2,3 A]QUINOLIZINE 2,4' PYRIMIDINE] 2' ONE; 6 (4 PYRIDYLMETHYL) 8 (3 NITROPHENYL)QUINOLINE; 9 (2 HYDROXY 3 NONYL)ADENINE; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; KETAMINE; MILRINONE; NEUROKININ 1 RECEPTOR; NEUROKININ 1 RECEPTOR AGONIST; PENTOBARBITAL; PHOSPHODIESTERASE I INHIBITOR; PHOSPHODIESTERASE II INHIBITOR; PHOSPHODIESTERASE III INHIBITOR; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE IV INHIBITOR; PHOSPHODIESTERASE V INHIBITOR; RS 14203; SUBSTANCE P [9 SARCOSINE 11 METHIONINE]; UNCLASSIFIED DRUG; VINPOCETINE; XYLAZINE; ZAPRINAST;

ANESTHESIA; ANESTHETIC RECOVERY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CEREBROSPINAL FLUID LEVEL; DRUG DISTRIBUTION; DRUG EFFECT; DRUG MECHANISM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; VOMITING;

EID: 0036152721     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704457     Document Type: Article

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