Activation of neuronal N-methyl-D-aspartate receptor channels by lipid emulsions

Anesthesia and Analgesia

Volumn 94, Issue 2, 2002, Pages 331-337

  Weigt, Henry U ^a   Georgieff, Michael ^a   Beyer, Cordian ^a   Föhr, Karl J ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ABBOLIPID; BICUCULLINE; CLINOLEIC; DIAZEPAM; DRUG CARRIER; ETOMIDATE; INTRALIPID; KETAMINE; LIPID EMULSION; LIPOFUNDIN MCT; LIPOFUNDIN N; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PICROTOXIN; PROPOFOL; SALVILIPID; STRUCTOLIPID;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG POTENCY; FETUS; MEMBRANE CURRENT; MOUSE; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; RECEPTOR INTRINSIC ACTIVITY;

EID: 0036148884     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/00000539-200202000-00018     Document Type: Article

References (26)

1. Pharmacokinetics, induction of anaesthesia and safety characteristics of propofol 6% SAZN vs propofol 1% SAZN and Diprivan-10 after bolus injection
2. Emulsion formulation reduces propofol's dose requirements and enhances safety
3. Physiochemical characterization of propofol-loaded emulsions and interaction with plasma proteins
4. Metabolic and neurologic effects of an intravenous medium-chain triglyceride emulsion
5. A putative fatty acid-binding domain of the NMDA receptor
6. Potentiation of NMDA receptor currents by arachidonic acid
7. Lipid mediators modulate NMDA receptor currents in a Xenopus oocyte expression system
8. Subunit- and site-specific pharmacology of the NMDA receptor channel
9. The N-methyl-D-aspartate antagonist CNS 1102 protects cerebral gray and white matter from ischemic injury following temporary focal ischemia in rats
10. Dopamine content and metabolism in mesencephalic and diencephalic cell cultures: Sex differences and effects of sex steroids
11. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
12. NMDA-induced whole-cell currents and single channel conductances in tectal neurons during two stages of early development of chicken
13. A receptors in cultured murine hippocampal neurons
14. Propofol inhibits cardiac L-type calcium current in guinea pig ventricular myocytes
15. Multiple mechanisms of ketamine blockade of N-methyl-D-aspartate receptors
16. Single-channel currents of NMDA type activated by L- and D-homocysteic acid in cerebellar granule cells in culture
17. Developmental changes in brain kynurenic acid concentrations
18. NMDA receptor redox sites: Are they targets for selective neuronal protection?
19. Review of the toxicologic properties of medium-chain triglycerides
20. Effects of temperature and volatile anesthetics on GABA(A) receptors
21. 129Xe: A compartment model
22. Pharmacokinetics and pharmacodynamics of propofol in a new solvent
23. How does xenon produce anaesthesia?
24. Propofol modulates the effects of chemoconvulsants acting at GABAergic, glycinergic, and glutamate receptor subtypes
25. Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain
26. Sensitivity of the developing rat brain to hypobaric/ischemic damage parallels sensitivity to N-methyl-aspartate neurotoxicity