In vivo airway surface liquid Cl- analysis with solid-state electrodes

Journal of General Physiology

Volumn 119, Issue 1, 2002, Pages 3-14

  Caldwell, Ray A ^a   Grubb, Barbara R ^a   Tarran, Robert ^a   Boucher, Richard C ^a   Knowles, Michael R ^a   Barker, Pierre M ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Cystic fibrosis; Defensins; Ion selective electrodes; Ionic strength; Mucus

Indexed keywords

DEFENSIN; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ADULT; ANIMAL EXPERIMENT; ARTICLE; BRONCHUS; CELL CULTURE; CHLORIDE TRANSPORT; CONTROLLED STUDY; CYSTIC FIBROSIS; DIAGNOSTIC ACCURACY; DOG; ELECTRODE; FEMALE; GENE MUTATION; HUMAN; HUMAN EXPERIMENT; ION CONDUCTANCE; ION TRANSPORT; IONIC STRENGTH; MALE; MONKEY; MOUSE; MUCUS; NONHUMAN; NOSE CAVITY; PATHOGENESIS; RABBIT; SENSITIVITY AND SPECIFICITY; SOLID STATE; SPECIES DIFFERENCE; TRACHEA; TRACHEOBRONCHIAL TREE;

ADULT; ANIMALS; BRONCHI; CHLORIDES; FEMALE; HUMANS; ION-SELECTIVE ELECTRODES; MACACA MULATTA; MALE; MICE; MICE, INBRED C57BL; MIDDLE AGED; NASAL CAVITY; RABBITS; SOLUTIONS; TRACHEA;

EID: 0036141446     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.119.1.3     Document Type: Article

References (52)

1. X-ray microanalysis of native airway surface liquid collected by cryotechnique
2. Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung
3. The innate immune system in cystic fibrosis lung disease
4. Regional differences in airway surface liquid composition
5. Regional differences in bioelectric properties and ion flow in excised canine airways
6. + transport in cystic fibrosis respiratory epithelia. Abnormal basal rate and response to adenylate cyclase activation
7. A comparative study of mammalian tracheal mucous glands
8. Airway surface liquid composition in mice
9. Cystic fibrosis
10. Volume flow, hydraulic conductivity and electrical properties across bovine tracheal epithelium in vitro: Effect of histamine
11. On the use of absorbing discs to sample mucosal surface liquids
12. Silver/silver chloride electrodes for measurement of potential difference in human bronchi
13. Transepithelial water permeability in microperfused distal airways. Evidence for channel-mediated water transport
14. Hyperventilation with dry air increases airway surface fluid osmolality in canine peripheral airways
15. Comparison of mucus glands in the tracheal bronchial tree of man and animals
16. Human beta-defensin-1 is a salt-sensitive antibiotic that is inactivated in cystic fibrosis
17. Sweat chloride analysis by chloride ion-specific electrode method using heat stimulation
18. Epithelial cells of the conducting airways: A species comparison
19. Elementary properties of ions in solutions
20. Conventional and modified nasal potential difference measurement: Clinical use in cystic fibrosis
21. Elemental content of airway surface liquid from infants with cystic fibrosis
22. Regulation of ion transport across porcine distal bronchi
23. Bioelectric properties and ion transport of excised rabbit trachea
24. Noninvasive in vivo fluorescence measurement of airway-surface liquid depth, salt concentration, and pH
25. Airway surface liquid osmolality measured using fluorophore-encapsulated liposomes
26. Elemental composition of human airway surface liquid in healthy and diseased airways
27. Ion composition of airway surface liquid of patients with cystic fibrosis as compared to normal and disease-control subjects
28. Studies in cystic fibrosis: Determination of sweat electrolytes in situ with direct reading electrodes
29. Is cystic fibrosis lung disease caused by abnormal ion composition or abnormal volume?
30. The use of polyethylene catheters to harvest ASL: Role of surface tension
31. Galvanic cells with liquid junction potentials
32. Effects of temperature, relative humidity, and mode of breathing on canine airway secretions
33. Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease
34. Efficient killing of inhaled bacteria in deltaF508 mice: Role of airway surface liquid composition
35. Deposition, clearance, and effects of aerosolized amiloride in sheep airways
36. Calibration of ion-selective electrodes for use in biological fluids
37. Role of CFTR in airway disease
38. CFTR is a conductance regulator as well as a chloride channel
39. Structure and function of the CFTR chloride channel
40. Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid
41. CFTR as a cAMP-dependent regulator of sodium channels
42. Effects of ozone on transepithelial potential of mouse trachea
43. Thin-film measurements of airway surface liquid volume/composition and mucus transport rates in vitro
44. The relative roles of passive surface forces and active ion transport in the modulation of airway surface liquid volume and composition
45. The CF salt controversy: In vivo observations and therapeutic approaches
46. Activity of abundant antimicrobials of the human airway
47. Lung disease in cystic fibrosis: Is airway surface liquid composition abnormal?
48. Altered NaCl concentration of airway surface liquid in cystic fibrosis
49. The genesis of cystic fibrosis lung disease
50. Reference range data base for serum chemistry and hematology values in laboratory animals