Retroviral-mediated gene transfer in primary murine and human T-lymphocytes

Applied Biochemistry and Biotechnology - Part B Molecular Biotechnology

Volumn 15, Issue 2, 2000, Pages 133-142

  Riviere, I ^a   Gallardo, H F ^a   Hagani, A B ^a   Sadelain, M ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Gene transfer; Lymphocyte; Retroviral vector; Transduction

Indexed keywords

VIRUS RECEPTOR;

ANIMAL CELL; ARTICLE; CELL DIVISION; DNA INTEGRATION; EXPRESSION VECTOR; GENE EXPRESSION; GENE TRANSFER; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; MURINE LEUKEMIA VIRUS; NONHUMAN; RETROVIRUS; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; VIRUS RECOMBINANT;

ANIMALIA; MAMMALIA; MURINAE; MURINE LEUKEMIA VIRUS; UNIDENTIFIED RETROVIRUS;

EID: 0033858961     PISSN: 10736085     EISSN: None     Source Type: Journal    
DOI: 10.1385/MB:15:2:133     Document Type: Article

References (70)

1. Methods for the construction of retroviral vectors and the generation of high-titer producers
2. High-efficiency retroviral-mediated gene transfer into human and nonhuman primate peripheral blood lymphocytes
3. Recombinant retroviruses pseudotyped with the vesicular stomatitis virus G glycoprotein mediate both stable gene transfer and pseudotransduction in human peripheral blood lymphocytes
4. Methods for retroviral-mediated gene transfer in murine primary T-lymphocytes
5. Activation conditions determine susceptibility of murine primary T lymphocytes to retroviral infection
6. Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death
7. Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection
8. Integration of murine leukemia virus DNA depends on mitosis
9. Evidence that retroviruses integrate into post-replication host DNA
10. Cell-surface receptors for retroviruses and implications for gene transfer
11. Lentiviral vectors - The promise of gene therapy within reach?
12. Rapid selection of antigen-specific T-Lymphocytes by retroviral transduction
13. Transport of cationic amino acids by the mouse ecotropic retrovirus receptor
14. Cell-surface receptor for ecotropic murine retroviruses is a basic amino-acid transporter
15. Cell-surface receptors for gibbon ape leukemia virus and amphotropic murine retrovirus are inducible sodium-dependent phosphate symporters
16. The dual-function hamster receptor for amphotropic murine leukemia virus (MuLV), 10A1 MuLV, and gibbon ape leukemia virus is a phosphate symporter
17. The HIV-1 envelope glycoproteins: Fusogens, antigens, and immunogens
18. A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection
19. Adenovirus - Facilitated infection of human cells with ecotropic retrovirus
20. Improved gene transfer into human lymphocytes using retroviruses with the gibbon ape leukemia virus envelope
21. High-effiency retroviral vector mediated gene transfer into human peripheral CD4+ T lymphocytes
22. Inhibition of VSV binding and infectivity by phosphatidylserine: Is phosphatidylserine a VSV-binding site?
23. Characterization of membrane components of the erythrocyte involved in vesicular stomatitis virus attachment and fusion at acidic pH
24. Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: Concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells
25. Efficient transduction by an amphotropic retrovirus vector is dependent on high-level expression of the cell surface virus receptor
26. The level of mRNA encoding the amphotropic retrovirus receptor in mouse and human hematopoietic stem cells is low and correlates with the efficiency of retrovirus transduction
27. Retrovirus - Mediated gene transfer into human hematopoietic stem cells
28. Endogenous retroviruses and the evolution of resistance to retroviral infection
29. Antiviral activity of autocrine interferon-beta requires the presence of a functional interferon type I receptor
30. Analysis of inhibition of retroviral reverse transcriptase
31. Blocking of retroviral infection at a step prior to reverse transcription in cells transformed to constitutively express interferon beta
32. + T lymphocytes suppresses HIV replication
33. + T cells
34. + T cells
35. Nonproductive human immunodeficiency virus type 1 infection in nucleoside-treated GO lymphocytes
36. HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latent viral structure
37. Lysis of RNA tumor viruses by human serum: Direct antibody-independent triggering of the classical complement pathway
38. + T lymphocytes in nonhuman primates using a gibbon ape leukemia virus-derived retroviral vector
39. Soluble CD4 molecules neutralize human immunodeficiency virus type 1
40. Retroviral expression of the human IL-2 gene in a murine T cell line results in cell growth autonomy and tumorigenicity
41. Gene transfer into humans: Immunotherapy of patients with advanced melanoma using tumor infiltrating lymphocytes modified by retroviral gene transduction
42. Effects of retroviral design on expression of human adenosine deaminase in murine bone marrow transplant recipients engrafted with genetically modified cells
43. Retroviral - Mediated transfer and expression of exogenous genes in primary lymphoid cells: Assaying for a viral transactivator activity in normal and malignant cells
44. An in vivo model of somatic cell gene therapy for human severe combined immunodeficiency
45. Lymphocytes as cellular vehicles for gene therapy in mouse and man
46. Improvement of gene transduction efficiency in T lymphocytes using retroviral vectors
47. High-efficiency gene transfer into normal and adenosine deaminase- deficient T lymphocytes is mediated by transduction on recombinant fibronectin fragments
48. Establishment of an optimized gene transfer protocol for human primary T lymphocytes according to clinical requirements
49. Green fluorescent protein as a selectable marker of fibronectin-facilitated retroviral gene transfer in primary human T lymphocytes
50. Peripheral blood lymphocytes as target cells of retroviral vector-mediated gene transfer
51. Transcriptional interference in avian retroviruses: Implications for the promoter insertion model of leukemogenesis
52. Comparison of expression in hematopoietic cells by retroviral vectors carrying two genes
53. The internal ribosomal entry site of encephalomyocarditis virus enables very reliable coexpression of two transgene in human primary T lymphocytes
54. Development of improved adenosine deaminase retroviral vectors
55. Cytokine signals are sufficient for HIV-1 infection of resting human T lymphocytes
56. Efficient transduction of human lymphocytes and CD34+ cells via human immunodeficiency virus-based gene transfer vectors
57. An early response of an AP1-junD complex during T-cell activation
58. Transactivation of the Moloney murine leukemia virus and T-cell receptor beta-chain enhancers by cbf and ets requires intact binding sites for both proteins
59. Point mutations in the Moloney murine leukemia virus enhancer identify a lymphoid-specific viral core motif and 1,3-phorbol myristate acetate- inducible element
60. Identification of ETS domain proteins in murine T lymphocytes that interact with the Moloney murine leukemia virus enhancer
61. Differential activation of human immunodeficiency virus type 1 and 2 transcription by specific T-cell activation signals
62. The T cell activation factor NF-ATc positively regulates HIV-1 replication and gene expression in T cells
63. Costimulation of transduced T lymphocytes via T cell receptor-CD3 complex and CD28 leads to increased transcription of integrated retrovirus
64. Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host range
65. Construction and properties of retrovirus packaging cells based on gibbon ape leukemia virus
66. Efficiency of in vivo gene transfer using murine retroviral vectors is strain-dependent in mice
67. Large-scale manufacturing of safe and efficient retrovirus packaging lines for use in immunotherapy protocols