Goniodomin A, an antifungal polyether macrolide, exhibits antiangiogenic activities via inhibition of actin reorganization in endothelial cells

Journal of Cellular Physiology

Volumn 190, Issue 1, 2002, Pages 109-116

  Abe, Mayumi ^a   Inoue, Daisuke ^a   Matsunaga, Kimihiro ^a   Ohizumi, Yasushi ^a   Ueda, Hiroshi ^b   Asano, Tomiko ^b   Murakami, Masahiro ^c   Sato, Yasufumi ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b INSTITUTE FOR DEVELOPMENTAL RESEARCH   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ANGIOGENESIS INHIBITOR; ANTIFUNGAL AGENT; COLLAGEN TYPE 1; GONIODOMIN A; MACROLIDE; POLYETHER;

ANIMAL CELL; ARTICLE; CATTLE; CELL LINE; CELL MIGRATION; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; CYTOSKELETON; DINOFLAGELLATE; DRUG MECHANISM; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; VASCULAR ENDOTHELIUM;

ACTINS; ALLANTOIS; ANGIOGENESIS INHIBITORS; ANIMALS; ANTIFUNGAL AGENTS; AORTA; CATTLE; CELL DIVISION; CELL MOVEMENT; CELLS, CULTURED; CHICK EMBRYO; CHORION; COLLAGEN; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; ETHERS; FIBROBLAST GROWTH FACTOR 2; GELS; HELA CELLS; HUMANS; LYMPHOKINES; LYSOPHOSPHOLIPIDS; MACROLIDES; MICROFILAMENTS; NEOVASCULARIZATION, PHYSIOLOGIC; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

BOVINAE; DINOPHYCEAE; GONIODOMA;

EID: 0036132385     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.10040     Document Type: Article

References (26)

1. Regulation and functions of Rho-associated kinase
2. Focal adhesion assembly
3. Angiogenesis in cancer and other diseases
4. Rho-stimulated contractility drives the formation of stress fibers and focal adhesions
5. Goniodomin A induces modulation of actomyosin ATPase activity mediated through conformational change of actin
6. Roles of two VEGF receptors, Flt-1 and KDR, in the signal transduction of VEGF effects in human vascular endothelial cells
7. Cell migration: A physically integrated molecular process
8. Powerful activation of skeletal muscle actomyosin ATPase by goniodomin A is highly sensitive to troponin/tropomyosin complex
9. Cellular actin and junction formation during reaggregation of adult rat hepatocytes into epithelial cell sheets
10. Goniodomin A, an antifungal polyether macrolide, increase the filamentous actin content 1321N1 human astrocytoma cells
11. Major pertussis-toxin-sensitive GTP-binding protein of bovine lung
12. Goniodomin A, a novel polyether macrolide from the dinoflagellate Goniodoma pseudogoniaulax
13. Application of physiologically active substances isolated from natural resources to pharmacological studies
14. Effects of cytochalasin B on muscle cells in tissue culture
15. Focal adhesions: A nexus for intracellular signaling and cytoskeletal dynamics
16. Autocrine activities of basic fibroblast growth factor: Regulation of endothelial cell movement, plasminogen activator synthesis, and DNA synthesis
17. Indispensable role of tissue-type plasminogen activator in growth factor-dependent tube formation of human microvascular endothelial cells in vitro
18. Roles of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase in the signal transduction of basic fibroblast growth factor in endothelial cells during angiogenesis
19. G protein βγ subunits induce stress fiber formation and focal adhesion assembly in a Rho-dependent manner in HeLa cells
20. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
21. Vascular-specific growth factors and blood vessel formation
22. Modulation of actomyosin ATPase by goniodomin A differs in types of cardiac myosin
23. Clarithromycin is a potent inhibitor of tumor-induced angiogenesis
24. Inhibition of tumor angiogenesis by roxithromycin, a 14-membered ring macrolide antibiotic
25. Antiangiogenic and antitumor effects of 14-membered ring macrolides on mouse B16 melanoma cells
26. Inhibitory effects of roxithromycin on tumor angiogenesis, growth and metastasis of mouse B16 melanoma