Loss of HLA molecules in B lymphomas is associated with an aggressive clinical course

British Journal of Haematology

Volumn 100, Issue 4, 1998, Pages 655-663

  Amiot, Laurence ^a   Onno, Myriam ^a   Lamy, Thierry ^b   Dauriac, Charles ^b   Le Prise, Pierre Yves ^b   Fauchet, Renée ^a   Drenou, Bernard ^a,c  

^a UNIVERSITÉ DE RENNES 1   (France)

^b PONTCHAILLOU UNIVERSITY HOSPITAL   (France)

^c Lab d'Hematologie Immunologie   (France)

Author keywords

HLA molecules; Immune surveillance; Lymphoma; Prognosis

Indexed keywords

HLA ANTIGEN;

ADULT; AGED; ANTIGEN DETECTION; ANTIGEN EXPRESSION; ARTICLE; B CELL LYMPHOMA; CANCER IMMUNOLOGY; CONTROLLED STUDY; DISEASE COURSE; FEMALE; FOLLICULAR LYMPHOMA; HLA SYSTEM; HUMAN; HUMAN CELL; IMMUNOSURVEILLANCE; LYMPHOPROLIFERATIVE DISEASE; MAJOR CLINICAL STUDY; MALE; NONHODGKIN LYMPHOMA; PRIORITY JOURNAL;

AGED; ATP-BINDING CASSETTE TRANSPORTERS; BETA 2-MICROGLOBULIN; DIAGNOSIS, DIFFERENTIAL; FEMALE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; LYMPHOMA, B-CELL; LYMPHOMA, FOLLICULAR; MALE; MIDDLE AGED; TUMOR CELLS, CULTURED;

EID: 0031929898     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1998.00631.x     Document Type: Article

References (46)

1. Amiot, L., Onno, M., Drénou, B., Lemarchand, B., Lamy, T., Semana, G. & Fauchet, R. (1996) Distribution of HLA-G alternative mRNAs including soluble forms in normal lymphocytes and in lymphoid cell-derived leukemia. European Journal of Immunogenetics, 23, 311-320.
2. Barnstable, C.J., Bodmer, W.F., Brown, G., Galfre, B.B., Milstein, C., Williams, A.F. & Ziegler, A. (1978) Production of monoclonal antibodies to group A erythrocytes. HLA and other cell surface antigens: new tools for genetic analysis. Cell, 14, 9-20.
3. Bicknell, D.C., Rowan, A. & Bodmer, W.F. (1994) Beta-2-microglobulin gene mutations: a study of established colorectal cell lines and fresh tumors. Proceeding of the National Academy of Sciences of the United States of America, 91, 4751-4756.
4. Cabrera, Th., Fernandez, M.A., Sierra, A., Garrido, A., Herruzo, A., Escobedo, A., Fabra, A. & Garrido, F. (1996) High frequency of altered HLA class I phenotypes in invasive breast carcinomas. Human Immunology, 50, 127-134.
5. Chen, H.L., Gabrilovich, D., Tampe, R., Girgis, K.R., Nadaf, S. & Carbone, D.P. (1996) A functionally defective allele of TAP1 results in loss of MHC class 1 antigen presentation in a human lung cancer. Nature Genetics, 13, 210-213.
6. Cromme, F.V., Airey, J., Heemels, M.T., Ploegh, H.L., Keating, P.J., Stern, P.L., Meijer, C.J.L.M. & Walboomers, J.M.M. (1994) Loss of transporter protein, encoded by the TAP-1 gene, is highly correlated with loss of HLA expression in cervical carcinomas. Journal of Experimental Medicine, 79, 335-340.
7. D'Alfonso, S., Savoia, P., Pitti, G., Peruccio, D., Pozzi, C., Crepaldi, T., Falda, M., Ficara, F., Resegotti, L. & Richiardi Momigliano, P. (1993) Quantitative expression of HLA class I molecules in acute non-lymphoblastic leukaemia cells. European Journal of Immunogenetics, 20, 165-173.
8. Drénou, B., Amiot, L., Lanson, B., Lamy, T., Grulois, I., Le Prisé, P.-Y. & Fauchet, R. (1997) Major histocompatibility complex (MHC) class I antigens expression in non-Hodgkin lymphoma. HLA and Cancer: Genetic Diversity of HLA Functional and Medical Implications (ed. by D. Charron), Vol. 2, pp. 761-762.
9. Elkins, W.L., Pickard, A. & Pierson, G.R. (1984) Deficient expression of class I HLA in some cases of acute leukemia. Cancer Immunology Therapy, 18, 91-100.
10. Ferrone, S. & Marincola, M. F. (1995) Loss of HLA class I antigens by melanoma cells: molecular mechanisms, functional significance and clinical relevance. Immunology Today, 16, 487-494.
11. Fuji, A., Ishitani, A. & Geraghty, D.E. (1994) A soluble form of HLA-G antigen is encoded by a messenger ribonucleic acid containing intron 4. Journal of Immunology, 153, 5516-5524.
12. Garridom F., Cabrera, T., Concha, A., Glew, S., Ruiz-Cabello, F. & Stern, P.L. (1993) Natural history of HLA expression during tumour development. Immunology Today, 14, 491-499.
13. Gobin, S.J.P., Peijnenburg, A., Keijsers, V. & van den Elsen, J. (1997) Site α is crucial for two routes of IFNγ-induced MHC class I transactivation: the ISRE-mediated route and a novel pathway involving CIITA. Immunity, 6, 601-611.
14. James, R.F.L., Edwards, S., Hui, K.M., Basset, P.D. & Grosveld, F. (1991) The effect of class II gene transfection on the tumourigenicity of the H-2K-negative mouse leukaemia cell line K36. 16. Immunology, 72, 213-218.
15. Kärre, K., Ljunggren, H.G., Piontek, G. & Kiessling, R. (1986) Selective rejection of H-2 deficient lymphoma variants suggests alternative immune defence strategy. Nature, 319, 675-678.
16. Korkolopoulou, P., Kaklamanis, L., Pezzlla, F., Harris, A.L. & Gatter, K.C. (1996) Loss of antigen-presenting molecules (MHC class I and TAP-1) in lung cancer. British Journal of Cancer, 73, 148-153.
17. Kurokohchi, K., Carrington, M., Mann, D.L., Simonis, T.B., Alexander-Miller, M.A., Feinston, S.M., Akatsuka, T. & Berzofsky, J.A. (1996) Expression of HLA class I molecules and the transporter associated with antigen processing in hepatocellular carcinoma. Hepatology, 23, 1181-1188.
18. Lanier, L.L. (1997) Natural killer cells: from no receptors to too many, Immunity, 6, 371-378.
19. Lee, N., Malacko, A.R., Ishitani, A., Chen, M.C., Bajorath, T., Marquardt, H. & Geraghty, D.E. (1995) The membrane-bound and soluble forms of HLA-G bind identical sets of endogenous peptides but differ with respect to TAP association, Immunity, 3, 591-600.
20. Lennert, K. & Feller, A.C. (1991) Lymphomes à cellules B (LMB). Histopathologie des Lymphomes Malins non-Hodgkiniens selon la Classification de Kiel Actualisée (ed. by K. Lennert and A. C. Feller), pp. 59-158, Douin Éditeurs, Paris.
21. Liao, N.S., BIX, M., Zijlstra, M., Jaenisch, R. & Raulet, D. (1991) MHC class I deficiency: susceptibility to natural killer (NK) cells and impaired NK activity. Science, 253, 199-202.
22. Limpens, J., Stad, R., Vos, C., De Vlaam, C., De Jong, D., Van Ommen, G.J.B., Schuuring, E. & Kluin, P.M. (1995) Lymphoma-associated translocation t(14;18) in blood B cells of normal individuals. Blood, 85, 2528-2536.
23. Martin, B.K., Chin, K.C., Olsen, J.C., Skinner, C.A., Dey, A., Ozato, K. & Ting, J.P.Y. (1997) Induction of MHC class I expression by the MHC transactivator CIITA. Immunity, 6, 591-600.
24. Medeiros, L.J., Gelb, A.B., Wolfson, K., Doggett, R., McGregor, B., Cox, R.S., Horning, S.J. & Warnke, R.A. (1993) Major histocompatibility complex class I and class II antigen expression in diffuse large cell and large cell immunoblastic lymphomas. American Journal of Pathology, 143, 1086-1097.
25. Miller, T.P., Lippman, S.M., Spier, C.M., Slymen, D.J. & Grogan, T.M. (1988) HLA-DR (Ia) immune phenotype predicts outcome for patients with diffuse large cell lymphoma. Journal of Clinical Investigation, 82, 370-372.
26. Möller, P., Herrmann, B., Moldenhauer, G. & Momburg, F. (1987) Defective expression of MHC class I antigens is frequent in B-cell lymphomas of high-grade malignancy. International Journal of Cancer, 40, 32-39.
27. Mömburg, F., Herrmann, B., Moldenhauer, G. & Möller, P. (1987) B-cell lymphomas of high grade malignancy frequently lack HLA-DR, -DP and -DQ antigens and associated invariant chain. International Journal of Cancer, 40, 598-603.
28. Münz, C., Holmes, N., King, A., Loke, Y.W., Colonna, M., Schild, H. & Ramensee, H.G. (1997) Human histocompatibility leukocyte antigen HLA-G molecules inhibit NKAT3 expressing natural killer cells. Journal of Experimental Medicine, 185, 385-391.
29. Ortman, B., Copeman, J., Lehner, P.J., Sadavisan, B., Herberg, J.A., Grandea, A.G., Riddell, S.R., Tampé, R., Spies, T., Trowsdale, J. & Cresswell, P. (1997) A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes. Science, 277, 1306-1309.
30. Pende, D., Sivori, S., Accame, L., Pareti, L., Falco, M., Geraghty, D., Le Bouteiller, P.P., Moretta, L. & Moretta, A. (1997) HLA-G recognition by human natural killer cells: involvement of CD94 both as inhibitory and as activating receptor complex. European Journal of Immunology, 27, 1875-1880.
31. Pérez-Villar, J.J., Melero, I., Navarro, F., Carretero, M., Bellon, T., Llano, M., Colonna, M., Geraghty, D.E. & Lopez-Botet, M. (1997) The CD94/NKG2a inhibitory receptor complex is involved in natural killer cell-mediated recognition of cells expressing HLA-G. Journal of Immunology, 158, 5736-5743.
32. Reith, W., Steimle, V. & Mach, B. (1995) Molecular defects in the bare lymphocyte syndrome and regulation of MHC class II genes. Immunology Today, 16, 539-546.
33. Sachs, L. & Lotem, J. (1993) Control of programmed cell death in normal and leukemic cells: new implications for therapy. Blood, 82, 15-21.
34. Savoia, P., D'Alfonso, S., Peruccio, D., Isabella, N., Falda, M., Rasegotti, L. & Richiardi, P. (1992) Loss of surface HLA class I molecules in leukemic myeloblasts is correlated with an increased leukocyte concentration at onset. Haematologica, 77, 127-129.
35. Schultze, J.L., Seamon, M.J., Michalak, S., Gribben, J.J.G. & Nadler, L.M. (1997) Autologous tumor infiltrating T cells cytotoxic for follicular lymphoma cells can be expanded in vitro. Blood, 89, 3806-3816.
36. Skov, S., Bregenholt, S. & Claesson, M.H. (1997) Class I ligation of human T cells activates the ZAP 70 and p56lck tyrosine kinases. leads to an alternative phenotype of the TCR/CD3 ∈-chain. and induces apoptosis. Journal of Immunology, 158, 3189-3196.
37. Söderström, K., Corliss, B., Lanier, L.L. & Phillips, J.H. (1997) CD94/ NKG2a is the predominant inhibitory receptor involved in recognition of HLA-G by decidual and peripheral blood NK cells. Journal of Immunology, 159, 1072-1075.
38. Solheim, J.C., Carreno, B.M. & Hansen, T.H. (1997) Are transporter associated with antigen processing (TAP) and tapasin class I MHC chaperones? Journal of Immunology, 158, 541-543.
39. Stam, N.J., Vroom, T.M., Peters, P.J., Pastoors, E.B. & Ploegh, M.L. (1990) HLA-A and HLA-B specific monoclonal antibodies reactive with free heavy chains in Western blots, in formalin-fixed, paraffin-embedded tissues sections and in cryo-immuno-electron microscopy. International Immunology, 2, 113-125.
40. Storkus. W.J., Howell, D.N., Salter, R.D., Dawson, J.R. & Cresswell, P. (1987) NK susceptibility varies inversely with target cell class I HLA antigen expression. Journal of Immunology, 138, 1657-1659.
41. The International Non-Hodgkin's Lymphoma Prognostic Factors Project (1993) A predictive model for aggressive non-Hodgin's lymphoma. New England Journal of Medicine, 329, 987-994.
42. Truman, J.P., Choqueux, C., Tschopp, J., Vedrenne, J., Le Deist, F., Charron, D. & Mooney, N. (1997) HLA class II-mediated death is induced via Fas/Fas ligand interaction in human splenic B lymphocytes. Blood, 89, 1996-2007.
43. Truman, J.P., Ericson, M.L., Choqueux-Séébold, C., Charron, D. & Mooney, N. (1994) Lymphocyte programmed cell death is mediated via HLA class II DR. International Immunology, 6, 887-896.
44. Woda, B.A., Racklin, B. & Rapaport, H. (1981) Altered expression of histocompatibility antigens on B large cell lymphomas. Blood, 57, 802-804.
45. Woodle, E.S., Smith, D.M., Bluestone, J.A., Kirkman, W.M., Green, D.R. & Skowronski, E.W. (1997) Anti-human class I MHC antibodies induce apoptosis by a pathway that is distinct from the Fas antigen-mediated pathway. Journal of Immunology, 158, 2156-2164.
46. Yoshino, T., Cao, L., Nishiuchi, R., Matsuo, Y., Yamadori, I., Kondo, E., Teramoto, N., Hayashi, Y., Takahashi, K., Kamikawaji, N. & Akagi, T. (1995) Ligation of HLA class II molecules promotes sensitivity to CD95 (Fas antigen, APO)-mediated apoptosis. European Journal of Immunology, 25, 2190-2194.