The fluorescence biodistribution and kinetics of aminolevulinic acid induced protoporphyrin IX in the bladder of a rat model with orthotopic urothelial carcinoma

Journal of Urology

Volumn 167, Issue 4 I, 2002, Pages 1848-1853

  Grönlund Pakkanen, Sari ^a,b   Wahlfors, Jarmo ^a,b   Mäkinen, Kimmo ^a,b   Pakkanen, Timo M ^a,b   Talja, Martti ^a,b   Ala Opas, Martti ^a,b   Alhava, Esko ^a,b   Moore, Ronald B ^a,b  

^a KUOPIO UNIVERSITY HOSPITAL   (Finland)

^b NONE

Author keywords

Aminolevulinic acid; Bladder; Bladder neoplasms; Photochemotherapy; Rats, inbred F344

Indexed keywords

AMINOLEVULINIC ACID; PROTOPORPHYRIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER CARCINOMA; BLADDER MUCOSA; CALCULATION; CAMERA; COMPUTER PROGRAM; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG ACCUMULATION; DRUG SELECTIVITY; FEMALE; FLUORESCENCE MICROSCOPY; IMAGE ANALYSIS; NONHUMAN; PHOTODYNAMIC THERAPY; PHOTOSENSITIZATION; PORPHYRIN METABOLISM; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; TISSUE DISTRIBUTION; UROGENITAL TRACT CANCER; UROTHELIUM;

EID: 0036126761     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(05)65247-0     Document Type: Article

References (24)

1. A simplified grading method of transitional cell carcinoma of the urinary bladder: Reproducibility, clinical significance and comparison with other prognostic parameters
2. Apparent failure of current intravesical chemotherapy prophylaxis to influence the long-term course of superficial transitional cell carcinoma of the bladder
3. Photodynamic therapy (PDT) in the treatment of patients with resistant superficial bladder cancer: A long-term experience
4. Photodynamic therapy: Principles and urologic applications
5. Endogenous protoporphyrin IX, a clinically useful photosensitizer for photodynamic therapy
6. Oral versus intravenous administration of 5-aminolaevulinic acid for photodynamic therapy
7. The importance of fluorescence distribution and kinetics of ala-induced ppix in the bladder in photodynamic therapy
8. Protoporphyrin-IX distribution and photodynamic effect in rat oesophagus after aminolaevulinic acid administration
9. New drugs and future developments in photodynamic therapy
10. Morphological effects of photodynamic therapy on rabbit bladder using Photofrin II and Photosan intravesically and intravenously
11. The morphological and functional changes in rat bladder following photodynamic therapy with phthalocyanine photosensitization
12. The morphological changes in rat bladder after photodynamic therapy with 5-aminolaevulinic acid-induced protoporphyrin IX
13. Photodynamic therapy with endogenous protoporphyrin IX: Basic principles and present clinical experience
14. Early clinical experience with 5-aminolevulinic acid for the photodynamic therapy of superficial bladder cancer
15. Biodistribution of Photofrin II and 5-aminolevulinic acid-induced protoporphyrin IX in normal rat bladder and bladder tumor models: Implications for photodynamic therapy
16. Biodistribution of protoporphyrin IX in rat urinary bladder after intravesical instillation of 5-aminolevulinic acid
17. Effect of photodynamic therapy on urinary bladder function: An experimental study with rats
18. Characterization of a novel transplantable orthotopic rat bladder transitional cell tumour model
19. The detection of phthalocyanine fluorescence in normal rat bladder wall using sensitive digital imaging microscopy
20. Fluorescence distribution and photodynamic effect of ALA-induced PP IX in the DMH rat colonic tumour model
21. Photodynamic therapy
22. Biodistribution and phototoxicity of 5-aminolevulinic acid-induced PpIX in an orthotopic rat bladder tumor model
23. Endoscopic detection of transitional cell carcinoma with 5-aminolevulinic acid: Results of 1012 fluorescence endoscopies
24. Photodynamic therapy in the management of bladder cancer