Biodistribution of Photofrin II® and 5-Aminolevulinic Acid-Induced Protoporphyrin IX in Normal Rat Bladder and Bladder Tumor Models: Implications for Photodynamic Therapy

Photochemistry and Photobiology

Volumn 67, Issue 5, 1998, Pages 573-583

  Xiao, Zhengwen ^a   Miller, Gerald G ^a   McCallum, Theresa J ^a   Brown, Kevin M ^a   Lown, J William ^a   Tulip, John ^a   Moore, Ronald B ^a,b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOLEVULINIC ACID; PHOTOFRIN II; PROTOPORPHYRIN;

ANIMAL; ARTICLE; BLADDER; BLADDER TUMOR; CELL CULTURE; DISEASE MODEL; FEMALE; METABOLISM; PATHOLOGY; PHOTOCHEMOTHERAPY; RAT; TISSUE DISTRIBUTION;

AMINOLEVULINIC ACID; ANIMALS; DIHEMATOPORPHYRIN ETHER; DISEASE MODELS, ANIMAL; FEMALE; PHOTOCHEMOTHERAPY; PROTOPORPHYRINS; RATS; TISSUE DISTRIBUTION; TUMOR CELLS, CULTURED; URINARY BLADDER; URINARY BLADDER NEOPLASMS;

EID: 0032060611     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1751-1097.1998.tb09457.x     Document Type: Article

References (34)

1. Dougherty, T. J. and S. L. Marcus (1992) Photodynamic therapy. Eur. J. Cancer 28A, 1734-1742.
2. Van Hillegersberg, R., J. K. Will and J. H. P. Wilson (1994) Current status of photodynamic therapy in oncology. Drugs 48, 510-527.
3. Foote, C. S. (1991) Definition of type I and type II photosensitized oxidation. Photochem. Photobiol. 54, 659.
4. Henderson, B. W. and T. J. Dougherty (1992) How does photodynamic therapy work? Photochem. Photobiol. 55, 145-157.
5. Nseyo, U. O., T. J. Dougherty, D. G. Boyle, W. R. Potter, R. Wolf, R. Huben and J. E. Pontes (1985) Whole bladder photodynamic therapy for transitional cell carcinoma of the bladder. Urology 26, 274-280.
6. Harty, J. I., M. Amin, T. J. Wieman, M. T. Tseng, D. Ackman and W. Broghamer (1989) Complications of whole bladder dihematoporphyrin ether photodynamic therapy. J. Urol. 141, 1341-1346.
7. Kennedy, J. C., R. H. Pottier and D. C. Pross (1990) Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience. J. Photochem. Photobiol. B 6, 143-148.
8. Cairnduff, F., M. R. Stringer, E. J. Hudson, D. V. Ash and S. B. Brown (1994) Superficial photodynamic therapy with topical 5-aminolevulinic acid for superficial primary and secondary skin cancer. Br. J. Cancer 69, 605-608.
9. Regula, J., A. J. MacRobert, A. Gorchein, G. A. Buonaccorsi, S. M. Thorpe, G. M. Spencer, A. R. Hatfield and S. G. Bown (1995) Photosensitization and photodynamic therapy of esophageal, duodenal, and colorectal tumors using 5-aminolevulinic acid induced protoporphyrin IX - a pilot study. Gut 36, 67-75.
10. Van Hillegersberg, R., J. Willen, O. Van den Berg, W. J. Kort, O. T. Terpstra and J. H. P. Wilson (1992) Selective accumulation of endogenously produced porphyrins in a liver metastasis model in rats. Gastroenterology 103, 647-651.
11. Divaris, D. X. G., J. C. Kennedy and R. H. Pottier (1990) Phototoxic damage to sebaceous glands and hair follicles of mice after systemic administration of 5-aminolevulinic acid correlates with localized protoporphyrin IX fluorescence. Am. J. Pathol. 136, 891-897.
12. Bedwell, J., A. J. MacRobert, D. Philips and S. G. Bown (1992) Fluorescence distribution and photodynamic effect of ALA-induced PpIX in the DMH rat colonic tumor model. Br. J. Cancer 65, 818-824.
13. Leveckis, J., J. L. Burn, N. J. Brown and M. W. R. Reed (1994) Kinetics of endogenous protoporphyrin IX induction by aminolevulinic acid: preliminary studies in the bladder. J. Urol. 152, 550-553.
14. Kriegmair, M., R. Baumgartner, W. Lumper, R. Waidelich and A. Hofstetter (1996) Early clinical experience with 5-aminolevulinic acid for the photodynamic therapy of superficial bladder cancer. Br. J. Urol. 77, 667-671.
15. Stocker, S., R. Knuchel, R. Sroka, M. Kriegmair, P. Steinbach and R. Baumgartner (1997) Wavelength dependent photodynamic effects on chemically induced rat bladder tumors following intravesical instillation of 5-aminolevulinic acid. J. Urol. 157, 357-361.
16. Taari, K., M. Talja, M. Riihela, S. Rannikko and R. Mokka (1992) Morphological effects of photodynamic therapy on rabbit bladder using Photofrin II and Photosan intravesically and intravenously. Br. J. Urol. 70, 616-621.
17. Windahl, T., Q. Peng, J. Moan, S. Hellsten, B. Axelsson and L. Lofgren (1993) Uptake and distribution of intravenously or intravesically administered photosensitizers in the rat. Cancer Lett. 75, 65-70.
18. Olfert, B., M. Cross and A. A. McWilliam (1993) Guide to the Care and Use of Experimental Animals, Vol. 1, 2nd ed. and Canadian Council on Animal Care, Vol. 2. Bradda Printing Services Inc., Ottawa, Ontario.
19. Olfert, B., M. Cross and A. A. McWilliam (1993) Guide to the Care and Use of Experimental Animals, Vol. 1, 2nd ed. and Canadian Council on Animal Care, Vol. 2. Bradda Printing Services Inc., Ottawa, Ontario.
20. Chin, J., S. Kadhim, B. Garcia, Y. S. Kim and S. Karlik (1991) Magnetic resonance imaging for detecting and treatment monitoring of orthotopic murine bladder tumor implants. J. Urol. 145, 1297-1301.
21. Xiao, Z., T. J. McCallum, K. M. Brown, G. G. Miller, S. B. Halls and R. B. Moore (1998) A novel transplantable orthotopic rat bladder transitional cell tumor model for experimental therapies. (Submitted Int Cancer)
22. Chang, S. C., A. J. MacRobert and S. G. Bown (1996) Biodistribution of protoporphyrin IX in rat urinary bladder after intravesical instillation of 5-aminolevulinic acid. J. Urol. 155, 1744-1748.
23. Loh, C. S., D. Vernon, A. J. MacRobert, J. Bedwell, S. G. Bown and S. B. Brown (1993) Endogenous porphyrin distribution induced by 5-aminolevulinic acid in the tissue layers of the gastrointestinal tract. J. Photochem. Photobiol. B 20, 47.
24. Loh, C. S., A. J. MacRobert, J. Bedwell, J. Regula, N. Krasner and S. G. Bown (1993) Oral versus intravenous administration of 5-aminolevulinic acid for photodynamic therapy. Br. J. Cancer. 68, 41-51.
25. Pottier, R. H., Y. F. A. Chow, J. P. Lapainte, T. G. Truscott, J. C. Kennedy and L. A. Beiner (1986) Non-invasive technique for obtaining fluorescence excitation and emission spectra in vivo. Photochem. Photobiol. 44, 679-687.
26. Pope, A. J., A. J. MacRobert, D. Phillips and S. G. Bown (1991) The detection of phthalocyanine fluorescence in normal rat bladder wall using sensitive digital imaging microscopy. Br. J. Cancer 64, 875-879.
27. Spikes, J. D. (1992) Quantum yields and kinetics of the photobleaching of hematoporphyrin, Photofrin II, tetra(4-sulfonatophenyl)-porphine and uroporphyrin. Photochem. Photobiol. 55, 797-808.
28. Hua, Z., S. L. Gibson, T. H. Foster and R. Hilf (1995) Effectiveness of 5-aminolevulinic acid-induced protoporphyrin as a photosensitizer for photodynamic therapy in vivo. Cancer Res. 55, 1723-1731.
29. Moore, R. B., G. G. Miller, K. Brown, R. Bhatnagar, J. Tulip and M. S. McPhee (1995) Urothelial conversion of 5-aminolevulinic acid to protoporphyrin IX following oral or intravesical administration. SPIE 2371, 284-286.
30. 14C-labeled tryptophan, its metabolites, glycine and glucose by the urinary bladder of the mouse. Invest. Urol. 3, 577-585.
31. Bridges, J. W., N. S. E. Sargent and D. G. Upshall (1979) Rapid absorption from the urinary bladder of a series of n-alkyl carbamate: a route for the recirculation of drug. Br. J. Pharmacol. 66, 283-289.
32. Kriegmair, M., R. Baumgartner, R. Knuchel, H. Stepp, F. Hofstadter and A. Hofstetter (1996) Detection of early bladder cancer by 5-aminolevulinic acid induced porphyrin fluorescence. J. Urol. 155, 105-110.
33. Chang, S. C., A. J. MacRobert and S. G. Bown (1996) Photodynamic therapy on rat urinary bladder with intravesical instillation of 5-aminolevulinic acid: light diffusion and histological changes. J. Urol. 155, 1749-1753.
34. Bachor, R., R. Hautmann and T. Hasan (1994) Comparison of two routes of photosensitizer administration for photodynamic therapy of bladder cancer. Urol. Res. 22, 21-23.