Differential behaviour of fluid liposomes toward mammalian epithelial cells and bacteria: Restriction of fusion to bacteria

Journal of Drug Targeting

Volumn 10, Issue 1, 2002, Pages 47-54

  Desjardins, A ^a   Chen, T ^b   Khalil, H ^a   Sayasith, K ^a   Lagace J ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

Author keywords

Bacteria; Cystic fibrosis; Fusion; Lipid mixing assay; Liposome

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBIOTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; DIMYRISTOYLPHOSPHATIDYLGLYCEROL; DIPALMITOYLPHOSPHATIDYLCHOLINE; LIPOSOME; TOBRAMYCIN;

AEROSOL; ARTICLE; BACTERIAL CELL; BACTERIAL KINETICS; BACTERIAL MEMBRANE; CELL FUSION; CHRONIC LUNG DISEASE; CONTROLLED STUDY; CYSTIC FIBROSIS; DRUG ACTIVITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG PENETRATION; ENCAPSULATION; EPITHELIUM CELL; ESCHERICHIA COLI; HOST CELL; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; MEMBRANE FUSION; OUTER MEMBRANE; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RESPIRATORY SYSTEM; TEMPERATURE;

BACTERIA; CELL LINE; DRUG COMPOUNDING; EPITHELIAL CELLS; ESCHERICHIA COLI; HUMANS; KINETICS; LIPOSOMES; PSEUDOMONAS AERUGINOSA; TEMPERATURE;

EID: 0036121203     PISSN: 1061186X     EISSN: None     Source Type: Journal    
DOI: 10.1080/10611860290007522     Document Type: Article

References (45)

1. "Isolation and characterisation of the outer and cytoplasmic membranes of Pseudomonas cepacia"
2. "Elaboration et évaluation de chémoliposomes à action bactéricide anti-Pseudomonas aeruginosa chez un modèle animal d'infection chronique"
3. "Eradication of mucoid Pseudomonas aeruginosa with fluid liposome-encapsulated tobramycin in an animal model of chronic pulmonary infection"
4. "In vitro kinetics of drug release and pulmonary retention of microencapsulated antibiotics in liposomal formulations in relation to the lipid composition"
5. "In vitro bactericidal efficacy of sub-MIC concentrations of liposome-encapsulated against Gram-negative and Gram-positive bacteria"
6. "Aerosolization of low phase transition temperature liposomal tobramycin as dry powder in an animal model of chronic pulmonary infection caused by Pseudomonas aeruginosa"
7. "The use of exogenous fluorescent probes for temperature measurements in single living cells"
8. "Proton-induced permeability and fusion of large unilamellar vesicles by covalently conjugated poly(2-ethylacrylic acid)"
9. "Antibody humanization: A case of the 'Emperor's new clothes"
10. "The cancer cell"
11. "Lipid polymorphism and the functional roles of lipids in biological membranes"
12. "Antimicrobial treatment of pulmonary colonization and infection by Pseudomonas aeruginosa in cystic fibrosis patients"
13. "Prospective controlled study of home and hospital therapy of cystic fibrosis pulmonary disease"
14. "Studies on the mechanism of membrane fusion. Role of head-group composition in calcium- and magnesium-induced fusion of mixed phospholipid vesicles"
15. "Influence of phospholipid asymmetry on fusion between large unilamellar vesicles"
16. "Inhibition of bacterial gene expression by fluidosomal encapsulated antisense"
17. "To fuse or not to fuse: The effects of electrostatic interactions, hydrophobic forces, and structural amphiphilicity on protein-mediated membrane destabilization"
18. "Resistance mechanisms in Pseudomonas aeruginosa and other nonfermentative Gram-negative bacteria"
19. "Two strains of Madin-Darby canine kidney (MDCK) cell line have distinct glycophospholipid compositions"
20. "Genetic and immunologic aspects of cystic fibrosis"
21. "Fluorescence method for measuring the kinetics of fusion between biological membranes"
22. "Pseudomonas aeruginosa infection in cystic fibrosis. Diagnostic and prognostic significance of Pseudomonas aeruginosa precipitins determined by means of crossed immunoelectrophoresis. A survey"
23. "Membrane fusion through point defects in bilayers"
24. "Pathogenesis of cystic fibrosis"
25. "Aggregation and calcium-induced fusion of phosphatidylcholine vesicle-tubulin complexes"
26. "Role of MexA-MexB-OprM in antibiotic efflux in Pseudomonas aeruginosa"
27. "Distribution of lipids in cytoplasmic and outer membranes of Escherichia coli K12"
28. "Aminoglycoside-resistance mechanisms for cystic fibrosis Pseudomonas aeruginosa isolates are unchanged by long-term, intermittent, inhaled tobramycin treatment"
29. "Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: A mechanism for virulence activation in the cystic fibrosis lung"
30. "The function of tight junction in maintaining differences in lipid composition between the apical and basolateral cell surface domains of MDCK cells"
31. "Resonance energy transfer assay of protein-mediated lipid transfer between vesicles"
32. "Content mixing and membrane integrity during membrane fusion driven by pairing of isolated v-SNAREs and t-SNAREs"
33. "Multiple antibiotic resistance and efflux"
34. "Evaluation of the pulmonary and systemic immunogenecity of fluidosomes, a fluid liposomal-tobramycin formulation for the treatment of chronic infections in lungs"
35. "Demonstration of a fusion mechanism between a fluid bactericidal liposomal formulation and bacterial cells"
36. "Therapeutic efficacy of liposome-encapsulated gentamicin in rat Klebsiella pneumoniae pneumonia in relation to impaired host defense and low bacterial susceptibility to gentamicin"
37. "The molecular biology of cystic fibrosis"
38. "Use of resonance energy transfer to monitor membrane fusion"
39. "Control of membrane fusion by phospholipid head groups. II. The role of phosphatidylethanolamine in mixtures with phosphatidate and phosphatidylinositol"
40. "Cystic fibrosis survival rates. The influence of allergy and Pseudomonas aeruginosa"
41. "Membrane fusion: Lipid vesicles as a model system"
42. "Pseudomonas aeruginosa and other related species"
43. "The effect of subinhibitory concentrations of antibiotics on adherence of Pseudomonas aeruginosa to cystic fibrosis (CF) and non-CF-affected tracheal epithelial cells"
44. "Cystic fibrosis"