Studies on aromatase inhibitors. III. Synthesis and biological evaluation of [(4-bromobenzyl)(4-cyanophenyl)amino]azoles and their azine analogs

Chemical and Pharmaceutical Bulletin

Volumn 45, Issue 3, 1997, Pages 482-486

  Okada, Minoru ^a   Yoden, Toru ^a   Kawaminami, Eiji ^a   Shimada, Yoshiaki ^a   Kudoh, Masafumi ^a   Isomura, Yasuo ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

aldosterone; aminopyrimidine; aromatase; estrogen

Indexed keywords

1,2,4 TRIAZINE DERIVATIVE; 1,2,4 TRIAZOLE DERIVATIVE; 4 [(4 BROMOBENZYL)(4 CYANOPHENYL)AMINO] 4H 1,2,4 TRIAZOLE; 4 [N (4 BROMOBENZYL) N (1,2,4 TRIAZOL 4 YL)AMINO]BENZONITRILE; 5 [(4 BROMOBENZYL)(4 CYANOPHENYL)AMINO]PYRIMIDINE; ALDOSTERONE; ANDROSTENEDIONE; AROMATASE INHIBITOR; CORTICOTROPIN; ESTROGEN; FADROZOLE; SERIC GONADOTROPIN; UNCLASSIFIED DRUG;

ALDOSTERONE RELEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AROMATIZATION; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; ESTROGEN SYNTHESIS; FEMALE; MICROSOME; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; ORAL DRUG ADMINISTRATION; OVARY; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0030933052     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.45.482     Document Type: Article

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