메뉴 건너뛰기




Volumn 88, Issue 3, 1999, Pages 313-318

Use of 'N-in-One' dosing to create an in vivo pharmacokinetics database for use in developing structure-pharmacokinetic relationships

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; AMIDE; ANILINE; DIMETHYL SULFONE; METHYL GROUP; NITROGEN; PHENYL GROUP; SULFONAMIDE; SULFONYLUREA; UREA;

EID: 0033008412     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js980292q     Document Type: Article
Times cited : (49)

References (11)
  • 1
    • 15444364122 scopus 로고
    • Combinatorial drug discovery: Which methods will produce the greatest value?
    • Ecker, D. J.; Crooke, S. T. Combinatorial drug discovery: which methods will produce the greatest value? Bio/Technology 1995, 3, 351-60.
    • (1995) Bio/Technology , vol.3 , pp. 351-360
    • Ecker, D.J.1    Crooke, S.T.2
  • 2
    • 0031000066 scopus 로고    scopus 로고
    • Simultaneous pharmacokinetic screening of a mixture of compounds in the dog using APCI/LC/MS/MS analysis for increased throughput
    • Berman, J.; Halm, K.; Adkison, K.; Shaffer, J. Simultaneous Pharmacokinetic Screening of a Mixture of Compounds in the Dog Using APCI/LC/MS/MS Analysis for Increased Throughput. J. Med. Chem. 1997, 40, 827-829.
    • (1997) J. Med. Chem. , vol.40 , pp. 827-829
    • Berman, J.1    Halm, K.2    Adkison, K.3    Shaffer, J.4
  • 3
    • 0031048025 scopus 로고    scopus 로고
    • The simultaneous determination of mixtures of drug candidates by liquid chromatography atmospheric pressure chemical ionization mass spectrometry as an in vivo drug screening procedure
    • Olah, T. V.; MCLoughlin, D. A.; Gilbert, J. D. The simultaneous determination of mixtures of drug candidates by liquid chromatography atmospheric pressure chemical ionization mass spectrometry as an in vivo drug screening procedure. Rapid Commun. Mass Spectrom. 1997, 11, 17-23.
    • (1997) Rapid Commun. Mass Spectrom. , vol.11 , pp. 17-23
    • Olah, T.V.1    McLoughlin, D.A.2    Gilbert, J.D.3
  • 4
    • 0031915533 scopus 로고    scopus 로고
    • Rapid determination of oral pharmacokinetics and plasma free fraction using cocktail approaches: Methods and application
    • Allen, M. C.; Shah, T. S.; Day, W. W. Rapid determination of oral pharmacokinetics and plasma free fraction using cocktail approaches: Methods and application. Pharm. Res. 1998, 15, 93-97.
    • (1998) Pharm. Res. , vol.15 , pp. 93-97
    • Allen, M.C.1    Shah, T.S.2    Day, W.W.3
  • 5
    • 0020570160 scopus 로고
    • Structure-pharmacokinetic relationships among the barbiturates in the rat
    • Toon, S.; Rowland, M. Structure-Pharmacokinetic Relationships Among the Barbiturates in the Rat. J. Pharmacol. Exp. Ther. 1983, 225, 752-763.
    • (1983) J. Pharmacol. Exp. Ther. , vol.225 , pp. 752-763
    • Toon, S.1    Rowland, M.2
  • 6
    • 0025786605 scopus 로고
    • Assessment of biotransformation capacity after oral administration of various model substances as a cocktail
    • Henschel, L.; Hoffmann, A. Assessment of Biotransformation Capacity After Oral Administration of Various Model Substances as a Cocktail. Z. Gastroenterol. 1991, 29, 645-649.
    • (1991) Z. Gastroenterol. , vol.29 , pp. 645-649
    • Henschel, L.1    Hoffmann, A.2
  • 7
    • 0021354652 scopus 로고
    • A comparison of the blood levels and urinary excretion of ethionamide and prothionamide in man
    • Jenner, P. J.; Ellard, G. A.; Gruer, P. J. K.; Aber, V. R. A comparison of the blood levels and urinary excretion of ethionamide and prothionamide in man. J. Antimicrob. Chemother. 1984, 13, 267-277.
    • (1984) J. Antimicrob. Chemother. , vol.13 , pp. 267-277
    • Jenner, P.J.1    Ellard, G.A.2    Gruer, P.J.K.3    Aber, V.R.4
  • 8
    • 0023188026 scopus 로고
    • Plasma levels of ethionamide and prothionamide in a volunteer following intravenous and oral dosages
    • Jenner, P. J.; Smith, S. E. Plasma levels of ethionamide and prothionamide in a volunteer following intravenous and oral dosages. Lepr. Rev. 1987, 58, 31-37.
    • (1987) Lepr. Rev. , vol.58 , pp. 31-37
    • Jenner, P.J.1    Smith, S.E.2
  • 10
    • 0031456698 scopus 로고    scopus 로고
    • Preclinical drug metabolism in the age of high-throughput screening: An industrial perspective
    • Rodrigues, A. D. Preclinical Drug Metabolism in the Age of High-Throughput Screening: An Industrial Perspective. Pharm. Res. 1997, 14, 1504-1510.
    • (1997) Pharm. Res. , vol.14 , pp. 1504-1510
    • Rodrigues, A.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.