Host background immunity and human immunodeficiency virus protective vaccines, a major consideration for vaccine efficacy in Africa and in developing countries

Clinical and Diagnostic Laboratory Immunology

Volumn 9, Issue 3, 2002, Pages 505-507

  Borkow, Gadi ^a   Bentwich, Zvi ^a  

^a HEBREW UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

BCG VACCINE; CD28 ANTIGEN; CD38 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CD8 ANTIGEN; HLA DR ANTIGEN; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; MITOGEN ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; AFRICA; CELLULAR IMMUNITY; CPG ISLAND; CYTOTOXIC T LYMPHOCYTE; DEVELOPING COUNTRY; DRUG EFFICACY; HELMINTHIASIS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMIGRATION; IMMUNE RESPONSE; MEMORY CELL; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; NOTE; PRIORITY JOURNAL; SCHISTOSOMA MANSONI; SIMIAN IMMUNODEFICIENCY VIRUS; SOUTHEAST ASIA; VIREMIA;

AFRICA; AIDS VACCINES; ANIMALS; DEVELOPING COUNTRIES; DRUG DESIGN; HELMINTHIASIS; HIV INFECTIONS; HUMANS; T-LYMPHOCYTES, CYTOTOXIC; TH1 CELLS; TH2 CELLS;

EID: 0036106388     PISSN: 1071412X     EISSN: None     Source Type: Journal    
DOI: 10.1128/CDLI.9.3.505-507.2002     Document Type: Note

References (46)

1. Cytotoxic T lymphocyte activity and CD8 subpopulations in children at risk of HIV infection
2. Profound suppression of cellular proliferation mediated by the secretions of nematodes
3. Induction of antigen-specific Th1-biased immune responses by plasmid DNA in schistosoma-infected mice with a preexistent dominant Th2 immune profile
4. Good worms or bad worms: Do worm infections affect the epidemiological patterns of other diseases?
5. Immune activation is a dominant factor in the pathogenesis of African AIDS
6. Immune activation in the context of HIV infection
7. Pathogenesis of AIDS in Africa - Lessons from the Ethiopian immigrants in Israel
8. Immune dysregulation in Ethiopian immigrants in Israel: Relevance to helminth infections?
9. Chronic immune activation associated with intestinal helminth infections results in impaired signal transduction and anergy
10. Helminths, human immunodeficiency virus and tuberculosis
11. Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus
12. In vivo protective anti-HIV immune responses in non-human primates through DNA immunization
13. Immuno-epidemiology of human geohelminthiasis: Ecological and immunological determinants of worm burden
14. Why do we not have an HIV vaccine and how can we make one?
15. The global burden of intestinal nematode infections - Fifty years on
16. The TH1-TH2 hypothesis of HIV infection: New insights
17. Cell-mediated immune response to human immunodeficiency virus (HIV) type 1 in seronegative homosexual men with recent sexual exposure to HIV-1
18. HIV-specific T-helper activity in seronegative health care workers exposed to contaminated blood
19. The Th1-Th2 hypothesis of HIV infection: New insights
20. Occurrence of human immunodeficiency virus type 1 (HIV-1)-specific cytolytic T cell activity in apparently uninfected children born to HIV-1-infected mothers
21. Effect of deworming on human T cell responses to mycobacterial antigens in helminth-exposed individuals before and after bacille Calmette-Guerin (BCG) vaccination
22. Resistance to HIV-1 infection among persistently seronegative prostitutes in Nairobi, Kenya
23. Lack of evidence for the dichotomy of TH1 and TH2 predominance in HIV-infected individuals
24. Protective immunity to intracellular parasites - A focus for vaccine research and a challenge to immunization programmes
25. HIV vaccines - Where are we going?
26. Immune activation, a co-factor for HIV transmission in Thailand?
27. Decreased CD4 and increased CD8 counts with T cell activation is associated with chronic helminth infection
28. Kinetics of Gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: A longitudinal analysis of rapid progressors and long-term asymptomatics
29. Human immunodeficiency virus (HIV) nef-specific cytotoxic T lymphocytes in noninfected heterosexual contact of HIV-infected patients
30. Immune responses to human immunodeficiency virus type 1 in exposed but uninfected individuals: Protection or chance?
31. Ability of HIV to promote a TH1 to THO shift and to replicate preferentially in TH2 and TH0 cells
32. Immunological modulation and evasion by helminth parasites in human populations
33. Cytokine patterns during the progression to AIDS
34. TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
35. Health profile of Ethiopian immigrants in Israel: An overview
36. The global impact of HIV/AIDS
37. Epidemiological and immunological study of HIV-seropositive Ethiopian immigrants in Israel
38. Protection of human immunodeficiency virus type 2-exposed seronegative macaques from mucosal simian immunodeficiency virus transmission
39. High levels of anti-human immunodeficiency virus type 1 (HIV-1) memory cytotoxic T-lymphocyte activity and low viral load are associated with lack of disease in HIV-1-infected long-term nonprogressors
40. Th1 versus Th2 responses in AIDS
41. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi
42. Impairment of tetanus toxoid-specific Th1-like immune responses in humans infected with Schistosoma mansoni
43. The immune response and immunopathology in infection with Schistosoma mansoni: A key role of major egg antigen Sm-p40
44. Rapid development of vaccine protection in macaques by live-attenuated simian immunodeficiency virus
45. Reduction in interleukin-2-producing cells but not Th1 to Th2 shift in moderate and advanced stages of human immunodeficiency virus type-1-infection: Direct analysis of intracellular cytokine concentrations in CD4+ CD8- T cells
46. Infection by different HIV-1 subtypes (B and C) results in a similar immune activation profile despite distinct immune backgrounds