Reversal of halophilicity in a protein-DNA interaction by limited mutation strategy

Structure

Volumn 10, Issue 5, 2002, Pages 629-637

  Bergqvist, Simon ^a   Williams, Mark A ^a   O'Brien, Ronan ^a   Ladbury, John E ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Halophilicity; Isothermal titration calorimetry; Metal binding; Protein recognition; Salt dependence of affinity; TATA binding protein

Indexed keywords

AMINO ACID; DNA; MUTANT PROTEIN; PROTEIN; SODIUM CHLORIDE; TATA BINDING PROTEIN; TRANSCRIPTION FACTOR; ARCHAEAL PROTEIN;

AMINO ACID COMPOSITION; ARCHAEBACTERIUM; ARTICLE; DNA BINDING; DNA PROTEIN COMPLEX; DNA STRUCTURE; EUKARYOTE; EVOLUTIONARY ADAPTATION; GENE MUTATION; GENETIC ANALYSIS; HIGH TEMPERATURE; MUTAGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DNA INTERACTION; PROTEIN FUNCTION; PYROCOCCUS; SEQUENCE HOMOLOGY; THERMOSTABILITY; TIME; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CALORIMETRY; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; TEMPERATURE;

AMINO ACID SEQUENCE; ANIMAL; ARCHAEAL PROTEINS; BINDING SITES; CALORIMETRY; DNA; HUMAN; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN STRUCTURE, TERTIARY; PYROCOCCUS; SEQUENCE ALIGNMENT; SODIUM CHLORIDE; SUPPORT, NON-U.S. GOV'T; TATA-BOX BINDING PROTEIN; TEMPERATURE; ANIMALS; HUMANS;

ARCHAEA; EUKARYOTA; PYROCOCCUS; PYROCOCCUS WOESEI;

EID: 0036106350     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(02)00749-9     Document Type: Article

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