Importance of secondary structural specificity determinants in protein folding: Insertion of a native β-sheet sequence into an α-helical coiled-coil

Protein Science

Volumn 11, Issue 6, 2002, Pages 1519-1531

  Kwok, Stanley C ^a   Mant, Colin T ^b   Hodges, Robert S ^a,b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

sheet to helix transition; Coiled coil; Hydrophobic effect; NN motif; Protein folding; Structural cassette mutagenesis

Indexed keywords

ALANINE; CHIMERIC PROTEIN; HUMAN IMMUNOGLOBULIN; IMMUNOGLOBULIN F(AB) FRAGMENT; LEUCINE; PROTEIN; SERINE; ASPARAGINE; HYBRID PROTEIN;

ALPHA HELIX; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; CONFORMATIONAL TRANSITION; GENE CASSETTE; GENE INSERTION; HYDROPHOBICITY; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MOLECULAR GENETICS;

INSERTION SEQUENCES;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ASPARAGINE; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT FUSION PROTEINS;

EID: 0036102158     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.4170102     Document Type: Article

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