HLA class II signals sensitize B lymphocytes to apoptosis via Fas/CD95 by increasing FADD recruitment to activated Fas and activation of caspases

Human Immunology

Volumn 63, Issue 5, 2002, Pages 375-383

  Blancheteau, Vincent ^a   Charron, Dominique ^a   Mooney, Nuala ^a  

^a INSERM   (France)

Author keywords

Apoptosis; B lymphocytes; CD95; FADD; Fas; MHC class II; Signals

Indexed keywords

CASPASE; CASPASE 3; CASPASE 8; FAS ANTIGEN; HLA ANTIGEN CLASS 2; HLA DR ANTIGEN; LIGAND; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PEPTIDE;

ANTIGEN PRESENTING CELL; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CHEMICAL INTERACTION; CONTROLLED STUDY; ENZYME ACTIVATION; HELPER CELL; HOMEOSTASIS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LYMPHOCYTE SUBPOPULATION; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; SENSITIZATION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANTIGENS, CD95; APOPTOSIS; B-LYMPHOCYTES; CARRIER PROTEINS; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CELLS, CULTURED; ENZYME ACTIVATION; EPITOPES; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; FLOW CYTOMETRY; GENES, MHC CLASS II; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; LYMPHOCYTE ACTIVATION; MEMBRANE POTENTIALS; MITOCHONDRIA; PLOIDIES; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

EID: 0036092399     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(02)00384-1     Document Type: Article

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