Classic D1 dopamine receptor antagonist R-(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H- 3-benzazepine hydrochloride (SCH23390) directly inhibits G protein-coupled inwardly rectifying potassium channels

Molecular Pharmacology

Volumn 62, Issue 1, 2002, Pages 119-126

  Kuzhikandathil, Eldo V ^a   Oxford, Gerry S ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; DOPAMINE 1 RECEPTOR BLOCKING AGENT; DOPAMINE 3 RECEPTOR; G PROTEIN COUPLED RECEPTOR; POTASSIUM CHANNEL; POTASSIUM ION; SOMATOSTATIN;

ANIMAL CELL; ARTICLE; CHINESE HAMSTER; CONTROLLED STUDY; DEPOLARIZATION; IC 50; ION CURRENT; MEMBRANE POTENTIAL; NONHUMAN; OVARY CELL; PHARMACOLOGICAL BLOCKING; POTASSIUM CURRENT; PRIORITY JOURNAL; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION;

(R)-2,3,4,5-TETRAHYDRO-8-CHLORO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL; ANIMALS; CHO CELLS; CRICETINAE; DOPAMINE ANTAGONISTS; ELECTROPHYSIOLOGY; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; GTP-BINDING PROTEINS; HUMANS; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RECEPTORS, DOPAMINE D1; TRANSFECTION;

EID: 0036088723     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.62.1.119     Document Type: Article

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