Do sex steroids regulate glutamine synthesis with age?

American Journal of Physiology - Endocrinology and Metabolism

Volumn 282, Issue 1 45-1, 2002, Pages

  Sone, Hirohito ^a   Shimano, Hitoshi ^a   Sakakura, Yuki ^a   Inoue, Noriyuki ^a   Amemiya Kudo, Michiyo ^b   Yahagi, Naoya ^b   Osawa, Mitsujiro ^a   Suzuki, Hiroaki ^a   Yokoo, Tomotaka ^a   Takahashi, Akimitsu ^a   Iida, Kaoruko ^a   Toyoshima, Hideo ^a   Iwama, Atsushi ^a   Yamada, Nobuhiro ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Glucocorticoids; Heart; Muscle; Rat

Indexed keywords

ESTRADIOL; GLUCOCORTICOID; GLUTAMATE AMMONIA LIGASE; GLUTAMINE; MESSENGER RNA; PROGESTERONE; SEX HORMONE;

ADRENALECTOMY; AGE; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HEART; HORMONE ACTION; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT STRAIN; REPRODUCTION; TIBIALIS ANTERIOR MUSCLE;

EID: 0036075743     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00117.2001     Document Type: Article

References (34)

1. Glucocorticoids regulate rat glutamine synthetase expression in a tissue-specific manner
2. Cloning, nucleotide sequence, and potential regulatory elements of the glutamine synthetase gene from murine 3T3-L1 adipocytes
3. Role of glutamine depletion in severe illness
4. The significance of sarcopenia in old age
5. Exercise interrupts ongoing glucocorticoid-induced muscle atrophy and glutamine synthetase induction
6. Regulation of aldosterone secretion in old rats
7. Glutamine metabolism in skeletal muscle
8. Influence of ovariectommy and estradiol treatment on calcium homeostasis during aging in rats
9. Implication de l'insuline et des glucocorticoïdes dans la fonte protéique musculaire chez le rat au cours du vieillissement
10. Progesterone as a partial glucocorticoid agonist in L929 mouse fibroblasts: Effects on cell growth, glutamine synthetase induction and glucocorticoid receptors
11. Is glutamine a conditionally essential amino acid?
12. Nutrition and immunity in the elderly
13. Regulation of the spatiotemporal pattern of expression of the glutamine synthetase gene
14. The aging pituitary in the rat
15. Chronological changes in sex steroid, gonadotropin and prolactin secretions in aging female rats displaying different reproductive states
16. Murine glutamine synthetase: Cloning, development regulation, and glucocorticoid inducibility
17. Dexamethasone regulates glutamine synthetase expression in rat skeletal muscles
18. Glucocorticoid-mediated induction of glutamine synthetase in skeletal muscle
19. Glucocorticoid receptor-mediated induction of glutamine synthetase in skeletal muscle cells in vitro
20. Glutamine synthetase induction by glucocorticoids is preserved in skeletal muscle of aged rats
21. Kinetic impairment of nitrogen and muscle glutamine metabolisms in old glucocorticoid-treated rats
22. Glutamine transport across skeletal muscle cells is impaired during aging
23. Age-related in protein synthesis measured in vivo in rat liver and gastrocnemius muscle
24. The possible role of glutamine in some cells of the immune system and the possible consequence for the whole animal
25. High affinity aldosterone binding sites (type I receptors) in rat heart
26. Age-related sarcopenia in humans is associated with reduced synthetic rates of specific muscle proteins
27. Glutamine synthetase from muscle
28. How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions
29. Glutamine metabolism and its physiologic importance
30. Pharmacokinetic/pharmacodynamic models for corticosteroid receptor down-regulation and glutamine synthetase induction in rat skeletal muscle by a receptor/gene-mediated mechanism
31. Aging of the female reproductive system
32. Effects of estradiol and progesterone on body composition, protein synthesis, and lipoprotein lipase in rats
33. Theories of biological aging
34. Aging and infectious diseases: State of the art