Association of a decreased number of d(CA) repeats in the matrix metalloproteinase-9 promoter with glomerulosclerosis susceptibility in mice

Journal of the American Society of Nephrology

Volumn 13, Issue 8, 2002, Pages 2068-2076

  Fornoni, Alessia ^a   Wang, Yingcai ^a   Lenz, Oliver ^a   Striker, Liliane J ^a   Striker, Gary E ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE B; GENOMIC DNA; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; RANTES; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR AP 2; TRANSCRIPTION FACTOR SP1;

ANIMAL CELL; ARTICLE; CELL TYPE; CONTROLLED STUDY; DINUCLEOTIDE REPEAT; DNA POLYMORPHISM; DNA SEQUENCE; ENZYME ACTIVITY; GENETIC MARKER; GENETIC PREDISPOSITION; GLOMERULOSCLEROSIS; MESANGIUM CELL; MOUSE; MOUSE STRAIN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIMPLE SEQUENCE REPEAT; TRANSCRIPTION REGULATION;

EID: 0036067848     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ASN.0000022421.86757.8D     Document Type: Article

References (46)

1. Matrix metalloproteinases in renal development and disease
2. Substrate hydrolysis by matrix metalloproteinase-9
3. Matrix metalloproteinase 9 (92-kDa gelatinase/type IV collagenase) from HT 1080 human fibrosarcoma cells: Purification and activation of the precursor and enzymic properties
4. Age-related changes in α1- and α2-chain type IV collagen mRNAs in adult mouse glomeruli: Competitive PCR
5. Glomerular extracellular matrix and growth factors in diffuse mesangial sclerosis
6. Dinucleotide repeat polymorphism of matrix metalloproteinase-9 gene is associated with diabetic nephropathy
7. Matrix metalloproteinase 9 level predicts optimal collagen deposition during early wound repair in humans
8. Resistance of young gelatinase B-deficient mice to experimental autoimmune encephalomyelitis and necrotizing tail lesions
9. Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction
10. MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes
11. Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms
12. Complete structure of the human gene for 92-kDa type IV collagenase: Divergent regulation of expression for the 92- and 72-kilodalton enzyme genes in HT-1080 cells
13. Murine matrix metalloproteinase 9 gene: 5′-upstream region contains cis-acting elements for expression in osteoclasts and migrating keratinocytes in transgenic mice
14. Amplification of IL-1β-induced matrix metalloproteinase-9 expression by superoxide in rat glomerular mesangial cells is mediated by increased activities of NF-κB and activating protein-1 and involves activation of the mitogen-activated protein kinase pathways
15. The integrin linked kinase (ILK) induces an invasive phenotype via AP-1 transcription factor-dependent up-regulation of matrix metalloproteinase 9 (MMP-9)
16. Dual regulation of IL-1β-mediated matrix metalloproteinase-9 expression in mesangial cells by NF-κB and AP-1
17. Functional polymorphism in the regulatory region of gelatinase B gene in relation to severity of coronary atherosclerosis
18. Functional polymorphism in the matrix metalloproteinase-9 promoter as a potential risk factor for intracranial aneurysm
19. The kidney disease of diabetes mellitus (KDDM): A cell and molecular biology approach
20. Effect of glucose on matrix metalloproteinase activity in mesangial cells
21. Mesangial cells from transgenic mice with progressive glomerulosclerosis exhibit stable, phenotypic changes including undetectable MMP-9 and increased type IV collagen
22. Modulation of neutral protease expression in human mesangial cells by hyperglycaemic culture
23. Relationships between mesangial cell proliferation and types I and IV collagen mRNA levels in vitro
24. IGF-1 decreases collagen degradation in diabetic NOD mesangial cells: Implications for diabetic nephropathy
25. Regulation of insulin-like growth factor I receptors in diabetic mesangial cells
26. Loss of differences in mesangial cell phenotype between diabetic and normal rats: Role of culture passages
27. Fibroblastic cultures from the diabetic db/db mouse: Demonstration of decreased insulin receptors and impaired responses to insulin
28. Enhanced collagen synthesis in cultured skin fibroblasts from insulin-dependent diabetic patients with nephropathy
29. Increased generation of superoxide by angiotensin II in smooth muscle cells from resistance arteries of hypertensive patients: Role of phospholipase D-dependent NAD(P)H oxidase-sensitive pathways
30. A potential role for protease nexin 1 overexpression in the pathogenesis of scleroderma
31. Differential regulation of glomerular gelatinase B (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in obese Zucker rats
32. Expression of extracellular matrix molecules in human mesangial cells in response to prolonged hyperglycaemia
33. Reversibility of glucose-induced changes in mesangial cell extracellular matrix depends on the genetic background
34. Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome
35. Dissociation of glomerular hypertrophy, cell proliferation, and glomerulosclerosis in mouse strains heterozygous for a mutation (Os) which induces a 50% reduction in nephron number
36. Nature and severity of the glomerular response to nephron reduction is strain-dependent in mice
37. Strain differences rather than hyperglycemia determine the severity of glomerulosclerosis in mice
38. Matrix accumulation in mesangial cells exposed to cyclosporine A requires a permissive genetic background
39. Glomerular endothelial cells synthesize collagens but little gelatinase A and B
40. Molecular cloning of mouse tissue inhibitor of metalloproteinases-3 and its promoter: Specific lack of expression in neoplastic JB 6 cells may reflect altered gene methylation
41. Cloning, genomic organization, and chromosomal localization of the Scya 5 gene encoding the murine chemokine RANTES
42. The inheritance of glomerulosclerosis in mice is controlled by multiple quantitative trait loci
43. Linkage of genetic markers on human chromosomes 20 and 12 to NIDDM in Caucasian sib pairs with a history of diabetic nephropathy
44. Genetic variation at the matrix metalloproteinase-9 locus on chromosome 20q12.2-13.1
45. Shortened microsatellite d(CA)21 sequence down-regulates promoter activity of matrix metalloproteinase 9 gene
46. Confluence-induced alterations in CpG island methylation in cultured normal human fibroblasts