Effect of glucose on matrix metalloproteinase activity in mesangial cells

Nephron

Volumn 79, Issue 3, 1998, Pages 293-298

  McLennan, Susan V ^a   Yue, Dennis K ^b   Turtle, John R ^b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b NONE

Author keywords

Diabetic nephropathy; Matrix metalloproteinase; Mesangium degradation

Indexed keywords

GELATIN; GLUCOSE; MATRIX METALLOPROTEINASE; MERCURY DERIVATIVE; PLASMIN;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DEGRADATION; DIABETIC NEPHROPATHY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SUBSTRATE; EXTRACELLULAR MATRIX; FETUS; HUMAN; HUMAN CELL; MESANGIUM; MESANGIUM CELL; PRIORITY JOURNAL;

CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; DIABETIC NEPHROPATHIES; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; FETUS; FIBRINOLYTIC AGENTS; GLOMERULAR MESANGIUM; GLUCOSE; HUMANS; METALLOENDOPEPTIDASES; METHIONINE; PHENYLMERCURIC ACETATE; PLASMIN; SUBSTRATE SPECIFICITY; SULFHYDRYL REAGENTS;

EID: 0031835337     PISSN: 00282766     EISSN: None     Source Type: Journal    
DOI: 10.1159/000045052     Document Type: Article

References (7)

1. Fisher E, McLennan S, Tada H, Heffernan S, Yue DK, Turtle JR: Interaction of ascorbic acid and glucose on the production of collagen and proteoglycan by fibroblasts. Diabetes 1991;40:371-376.
2. Ayo S, Radnik RA, Glass WF, Garoni J, Rampt ER, Appling DR, Kreisberg JI: Increased extracellular matrix synthesis and mRNA in mesangial cells grown in high-glucose medium. Am J Physiol 1991;260:F185-F191.
3. Pugliese G, Pricci F, Pugliese F, Mene P, Lenti L, Andreani D, Galli G, Casini A, Bianchi S, Rotella CM, Di Mario U: Mechanisms of glucose-enhanced extracellular matrix accumulation in rat glomerular mesangial cells. Diabetes 1994;43:478-490.
4. The Diabetes Control and Complications Trial Research Group: The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993;329:977-986.
5. Matrisian L: Metalloproteinases and their inhibitors in matrix remodelling. Trends Genet 1990;6:121-125.
6. McLennan S, Fisher E, Yue DK, Turtle JR: High glucose concentration causes a decrease in mesangium degradation. Diabetes 1994;43: 1041-1045.
7. Reckelhoff JF, Tygart VL, Mitias MM, Walcott JL: STZ-induced diabetes results in decreased activity of glomerular cathepsin and metalloproteinase in rats. Diabetes 1993;42:1425-1432.