Mesangial cells from transgenic mice with progressive glomerulosclerosis exhibit stable, phenotypic changes including undetectable MMP-9 and increased type IV collagen

Laboratory Investigation

Volumn 75, Issue 6, 1996, Pages 791-799

  Jacot, Terry A ^a   Striker, Gary E ^a   Stetler Stevenson, MaryAlice ^b   Striker, Liliane J ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 4; GELATINASE A; GELATINASE B; GROWTH HORMONE; MESSENGER RNA; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; COLLAGEN DEGRADATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GENE EXPRESSION; GLOMERULOSCLEROSIS; MESANGIUM CELL; NONHUMAN; ONCOGENE C MYC; PRIORITY JOURNAL; TRANSGENIC MOUSE; UREMIA;

ANIMALS; CATTLE; CELLS, CULTURED; COLLAGEN; COLLAGENASES; DNA PRIMERS; GELATINASES; GLOMERULAR MESANGIUM; GLOMERULONEPHRITIS; GROWTH HORMONE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; METALLOENDOPEPTIDASES; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, TRANSGENIC; POLYMERASE CHAIN REACTION;

EID: 0030465719     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Adler S, Striker LJ, Striker GE, Perkinson DT, Hibbert J, and Couser WG (1986). Studies of progressive glomerular sclerosis in the rat. Am J Pathol 123:553-562.
2. Baricos WH (1995). Chronic renal disease: Do metalloproteinase inhibitors have a demonstrable role in extracellular matrix accumulation? Curr Opin Nephrol Hypertens 4:365-368.
3. r 72:000 type IV collagenase and interstitial collagenase in human tumorigenic cell lines. Cancer Res 50:6184-6191.
4. Carome MA, Striker LJ, Peten EP, Elliot SJ, Yang CW, Stetler-Stevenson WG, Reponen P, Tryggvason K, and Striker GE (1994). Assessment of 72-kilodalton gelatinase and TIMP-1 gene expression in normal and sclerotic murine glomeruli. J Am Soc Nephrol 5:1391-1399.
5. Carome MA, Striker LJ, Peten EP, Moore J, Yang CW, Stetler-Stevenson WG, and Striker GE (1993). Human glomeruli express tissue inhibitor of metalloproteinases I (TIMP-1) mRNA and TIMP-2 protein and mRNA. Am J Physiol 264:F923-F929.
6. Conti FG, Striker U, Elliot SJ, Adreani D, and Striker GE (1988). Synthesis and release of insulin-like growth factor I by mesangial cells in culture. Am J Physiol 255:F214-F219.
7. Doi T, Striker LJ, Elliot SJ, Conti FG, and Striker GE (1989). Insulin-like growth factor-1 is a progression factor for human mesangial cells. Am J Pathol 134:395-404.
8. Doi T, Striker LJ, Gibson CC, Agodoa LYC, Brinster R, and Striker GE (1990). Glomerular lesions in mice transgenic for growth hormone and insulin-like growth factor-1 I: Relationship between increased glomerular size and mesangial sclerosis. Am J Pathol 137:541-552.
9. Doi T, Striker LJ, Kimata K, Peten EP, Yamada Y, and Striker GE (1991). Glomerulosclerosis in mice transgenic for growth hormone: Increased mesangial extracellular matrix is correlated with kidney mRNA levels. J Exp Med 173:1287-1290.
10. Doi T, Striker LJ, Quaife C, Conti FG, Palmiter R, Behringer R, Brinster R, and Striker GE (1988). Progressive glomerulosclerosis develops in transgenic mice chronically expressing growth hormone and growth hormone releasing factor but not in those expressing insulin-like growth factor-1. Am J Pathol 131:398-403.
11. Elliot SJ, Striker LJ, Hattori M, Yang CW, He CJ, Peten EP, and Striker GE (1993). Mesangial cells from diabetic NOD mice constitutively secrete increased amounts of insulin-like growth factor-I. Endocrinology 133:1783-1788.
12. Galis ZS, Sukhova GK, Lark MW, and Libby P (1994). Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. J Clin Invest 94:2493-2503.
13. Hammerman MR and Miller SB (1993). The growth hormone insulin-like growth factor axis in kidney revisited. Am J Physiol 265:F1-F14.
14. Hana V and Murphy LJ (1994). Interdependence of epidermal growth factor and insulin-like growth factor-I expression in the mouse uterus. Endocrinology 135:107-112.
15. He CJ, Striker LJ, Tsokos M, Yang CW, and Striker GE (1995). Relationships between mesangial cell proliferation and types I and IV collagen mRNA levels in vitro. Am J Physiol 269:C554-C562.
16. Himelstein BP, Canete-Soler R, Bernhard EJ, Dilks DW, and Muschel RJ (1995). Metalloproteinases in tumor progression: The contribution of MMP-9. Invas Metastas 14:246-258.
17. Huhtala P, Chow L, and Tryggvason K (1990). Structure of the human type IV collagenase gene. J Biol Chem 265: 11077-11082.
18. Huhtala P, Tuuttila A, Chow L, Lohi J, Keski-Oja J, and Tryggvason K (1991). Complete structure for gene of the 92 kD collagenase. J Biol Chem 266:16485-16490.
19. Kitamura M, Burton S, English J, Kawachi H, and Fine LG (1995). Transfer of a mutated gene encoding active transforming growth factor-β1 suppresses mitogenesis and IL-1 response in the glomerulus. Kidney Int 48:1747-1757.
20. Knowlden J, Martin J, Davies M, and Williams JD (1995). Metalloproteinase generation by human glomerular epithelial cells. Kidney Int 47:1682-1689.
21. Lohi J and Keski-Oja J (1995). Calcium ionophores decrease pericellular gelatinolytic activity via inhibition of 92-kDa gelatinase expression and decrease of 72-kDa gelatinase activation. J Biol Chem 270:17602-17609.
22. Lovett DH, Johnson RJ, Marti HP, Martin J, Davies M, and Couser WG (1992). Structural characterization of the mesangial cell type IV collagenase and enhanced expression in a model of immune complex-mediated glomerulonephritis. Am J Pathol 141:85-98.
23. MacKay K, Striker LJ, Elliot S, Pinkert CA, Brinster R, and Striker GE (1988). Glomerular, epithelial, mesangial, and endothelial cell lines from transgenic mice. Kidney Int 33: 677-684.
24. MacKay K, Striker LJ, Stauffer JW, Doi T, Agodoa LY, and Striker GE (1989). Transforming growth factor-β murine glomerular receptors and responses of isolated glomerular cells. J Clin Invest 83:1160-1167.
25. Marti HP, Lee L, Kashgarian M, and Lovett DH (1994). Transforming growth factor β1 stimulates glomerular mesangial cell synthesis of the 72 kD type IV collagenase. Am J Pathol 144:82-94.
26. Marti HP, McNeil L, Davies M, Martin J, and Lovett DH (1993). Homology cloning of rat 72 kD type IV collagenase: Cytokine and second-messenger inducibility in glomerular mesangial cells. Biochem J 291:441-446.
27. Martin J, Knowlden J, Davies M, and Williams JD (1994). Identification and independent regulation of human mesangial cell metalloproteinases. Kidney Int 46:877-885.
28. Matsubara M, Girard MT, Kublin CL, Cintron C, and Fini E (1991). Differential roles for two gelatinolytic enzymes of the matrix metalloproteinase family in the remodeling cornea. Dev Biol 147:425-439.
29. Morel-Maroger Striker L, Killen P, Chi E, and Striker GE (1984). The composition of glomerulosclerosis: 1. Studies in focal sclerosis, crescentic glomerulonephritis, and membranoproliferative glomerulonephritis. Lab Invest 51:181-192.
30. Nakamura T, Fukui M, Ebihara I, Osada S, Tomino Y, and Koide H (1994). Abnormal gene expression of matrix metalloproteinases and their inhibitor in glomeruli from diabetic rats. Renal Physiol Biochem 17:316-325.
31. Pesce CM, Striker LJ, Peten EP, Elliot SJ, and Striker GE (1991). Glomerulosclerosis at both early and late stages is associated with increased cell turnover in mice transgenic for growth hormone. Lab Invest 65:601-605.
32. 2- chain type IV collagen mRNAs in adult mouse glomeruli: Competitive PCR. Am J Physiol 263:F951-F957.
33. Peten EP, Striker LJ, Fogo A, Ichikawa I, Patel A, and Striker GE (1994). The molecular basis of increased glomerulosclerosis after blockade of the renin angiotensin system in growth hormone transgenic mice. Mol Med 1:33-54.
34. Peten EP, Striker LJ, Garcia-Perez A, and Striker GE (1993). Studies by competitive PCR of glomerulosclerosis in growth hormone transgenic mice. Kidney Int 43:S55-S58.
35. Pugliese F, Ferrario RG, Ciavolella A, Tamburin M, Benatti L, Casini A, Patrono C, and Salvati P (1995). Growth abnormalities in cultured mesangial cells from rats with spontaneous glomerulosclerosis. Kidney Int 47:106-113.
36. Salo T, Makela M, Kylmaniemi M, Autio-Harmainen H, and Larjava H (1994). Expression of matrix metalloproteinase-2 and -9 during early human wound healing. Lab Invest 70: 176-182.
37. Schnaper HW (1995). Balance between matrix synthesis and degradation: A determinant of glomerulosclerosis. Pediatr Nephrol 9:104-111.
38. Sharma K and Ziyadeh F (1994). The emerging role of transforming growth factor-β in kidney diseases. Am J Physiol 266:F829-F842.
39. Stetler-Stevenson WG (1995). Progelatinase A activation during tumor cell invasion. Invasion Metastasis 14:259-268.
40. Striker LJ, Doi T, Elliot S, and Striker GE (1989). The contribution of glomerular mesangial cells to progressive glomerulosclerosis. Semin Nephrol 9:318-328.
41. + antiport activity and cell growth in cultured skin fibroblasts of IDDM patients with nephropathy. Diabetes 41:1239-1246.
42. Wolthuis A, Boes A, and Grond J (1993). Cell density modulates growth, extracellular matrix, and protein synthesis of cultured rat mesangial cells. Am J Pathol 143:1209-1219.