The BaeSR two-component regulatory system activates transcription of the yegMNOB (mdtABCD) transporter gene cluster in Escherichia coli and increases its resistance to novobiocin and deoxycholate

Journal of Bacteriology

Volumn 184, Issue 15, 2002, Pages 4168-4176

  Baranova, Natalya ^a   Nikaido, Hiroshi ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYCHOLIC ACID; GENE PRODUCT; HYBRID PROTEIN; NOVOBIOCIN; PROTEIN BAESR; PROTEIN MDTABCD; PROTEIN YEGM; PROTEIN YEGN; PROTEIN YEGO; PROTEIN YGCL; PROTEIN YICO; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; CELL DIVISION; CONTROLLED STUDY; DNA SEQUENCE; DRUG SENSITIVITY; DRUG TRANSPORT; ESCHERICHIA COLI; GENE CLUSTER; GENE CONTROL; GENE DISRUPTION; GENE EXPRESSION; GENE MUTATION; GENETIC CODE; GENETIC SCREENING; GENETIC TRANSCRIPTION; MOLECULAR CLONING; NONHUMAN; OPERON; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; REGULATOR GENE; REGULATORY MECHANISM; SEQUENCE ANALYSIS; TRANSCRIPTION INITIATION; TRANSPORT KINETICS;

ANTI-BACTERIAL AGENTS; DEOXYCHOLIC ACID; DRUG RESISTANCE, BACTERIAL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ESCHERICHIA COLI; GENE DELETION; GENES, BACTERIAL; MEMBRANE TRANSPORT PROTEINS; MULTIGENE FAMILY; NOVOBIOCIN; OPERON; PLASMIDS; PROMOTER REGIONS (GENETICS); REGULON; TRANSCRIPTION, GENETIC;

ANIMALIA; ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0036066806     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.184.15.4168-4176.2002     Document Type: Article

References (43)

1. A protein that activates expression of a multidrug efflux transporter upon binding the transporter substrates
2. Alteration of the repression activity of MarR, the negative regulator of the Escherichia coli marRAB locus, by multiple chemicals in vitro
3. Differential expression of over 60 chromosomal genes in Escherichia coli by constitutive expression of MarA
4. Purification and ligand binding of EmrR, a regulator of a multidrug transporter
5. The multidrug efflux protein NorM is a prototype of a new family of transporters
6. Genetic and functional analysis of the multiple antibiotic resistance (mar) locus in Escherichia coli
7. Salicylate induction of antibiotic resistance in Escherichia coli: Activation of the mar operon and a mar-independent pathway
8. Protein phosphorylation affects binding of the Escherichia coli transcription activator UhpA to the uhpT promoter
9. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
10. Redox signalling and gene control in the Escherichia coli soxRS oxidative stress regulon - A review
11. Purification of ArcA and analysis of its interaction with the pfl promoter-regulatory region
12. Position and density effects on repression by stationary and mobile DNA-binding proteins
13. Amplifiable resistance to tetracycline, chloramphenicol, and other antibiotics in Escherichia coli: Involvement of a non-plasmid-determined efflux of tetracycline
14. QacR is a repressor protein that regulates expression of the Staphylococcus aureus multidrug efflux pump QacA
15. Relative binding affinities of OmpR and OmpR-phosphate at the ompF and ompC regulatory sites
16. Two-component and phosphorelay signal transduction
17. EmrR is a negative regulator of the Escherichia coli multidrug resistance pump EmrAB
18. Responses to molecular oxygen
19. Transcriptional control mediated by the ArcA two-component response regulator protein of Escherichia coli: Characterization of DNA binding at target promoters
20. The local repressor AcrR plays a modulating role in the regulation of acrAB genes of Escherichia coli by global stress signals
21. Genes acrA and acrB encode a stress-induced efflux system of Escherichia coli
22. The putative response regulator BaeR stimulates multidrug resistance of Escherichia coli via a novel multidrug exporter system, MdtABC
23. Novel members of the two-component signal transduction genes in Escherichia coli
24. Multidrug efflux pumps of gram-negative bacteria
25. Analysis of a complete library of putative drug transporter genes in Escherichia coli
26. Overexpression of the response regulator EvgA of the two-component signal transduction system modulates multidrug resistance transporters
27. EvgA of the two-component signal transduction system modulates production of the YhiUV multidrug transporter in Escherichia coli
28. AcrAB efflux pump plays a major role in the antibiotic resistance phenotype of Escherichia coli multiple-antibiotic-resistance phenotype (Mar) mutants
29. Comparative genomics of microbial drug efflux systems
30. Microbial genome analyses: Global comparisons of transport capabilities based on phylogenies, bioenergetics and substrate specificities
31. Signalling pathways in two-component phosphorelay systems
32. Liquid chromatographic procedure for the determination of novobiocin residues in bovine milk: Interlaboratory study
33. Phylogenetic characterization of novel transport protein families revealed by genome analyses
34. Control of cell division in Escherichia coli: Regulation of transcription of ftsQA involves both rpoS and SdiA-mediated autoinduction
35. RobA-induced multiple antibiotic resistance largely depends on the activation of the AcrAB efflux
36. A factor that positively regulates cell division by activating transcription of the major cluster of essential cell division genes of Escherichia coli
37. Global impact of sdiA amplification revealed by comprehensive gene expression profiling of Escherichia coli
38. Histidine kinases and response regulator proteins in two-component signalling systems
39. Role of the acrAB locus in organic solvent tolerance mediated by expression of marA, soxS, or robA in Escherichia coli
40. The EmrR protein represses the Escherichia coli emrRAB multidrug resistance operon by directly binding to its promoter region
41. Cross-linked complex between oligomeric periplasmic lipoprotein AcrA and the inner-membrane-associated multidrug efflux pump AcrB from Escherichia coli